In vitro glucocorticoid resistance in childhood leukemia correlates with receptor affinity determined at 37°C, but not with affinity determined at room temperature [12]

Leukemia

Volumn 16, Issue 9, 2002, Pages 1882-1884

  Haarman, E G ^a   Kaspers, G J L ^a   Pieters, R ^b   Rottier, M M A ^a   Den Boer, M L ^b   Janka Schaub, G E ^c   Veerman, A J P ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b SOPHIA CHILDREN S HOSPITAL   (Netherlands)

^c COALL Study Group ^*  (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; PREDNISOLONE;

ACUTE LYMPHOBLASTIC LEUKEMIA; APOPTOSIS; CHILD; CHILDHOOD LEUKEMIA; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORRELATION ANALYSIS; DISSOCIATION CONSTANT; HUMAN; IMMUNOPHENOTYPING; IN VITRO STUDY; LC 50; LETTER; PRIORITY JOURNAL; PROGNOSIS; RECEPTOR AFFINITY; ROOM TEMPERATURE; SCATCHARD PLOT; T LYMPHOCYTE; TEMPERATURE DEPENDENCE;

EID: 0036736557     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2402606     Document Type: Letter

References (8)

1. Prednisolone resistance in childhood acute lymphoblastic leukemia: Vitro-vivo correlations and cross-resistance to other drugs
2. Glucocorticoid receptors and resistance to glucocorticoids in hematologic malignancies
3. Impact of treatment efficacy on the prognostic value of glucocorticoid receptor levels in childhood acute lymphoblastic leukemia
4. Lack of correlation between glucocorticoid receptor levels, response to prednisone monotherapy and relapse-free survival in childhood leukemia
5. Glucocorticoid receptors in immunological subtypes of childhood acute lymphocytic leukemia cells: A Pediatric Oncology Group Study
6. Glucocorticoid receptors in childhood acute non-lymphocytic leukemia
7. Temperature dependence of glucocorticoid binding in sensitive and refractory murine leukaemia cells
8. Glucocorticoid receptors in childhood acute lymphocytic leukemia