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Volumn 25, Issue 5, 2002, Pages 413-420

Oral Administration of Freshly Expressed Juice of Echinacea Purpurea Herbs Fail to Stimulate the Nonspecific Immune Response in Healthy Young Men: Results of a Double-Blind, Placebo-Controlled Crossover Study

Author keywords

Echinacea; Immune stimulation; Interleukin 1 ; Phagocytosis; Phytomedicine; Tumor necrosis factor

Indexed keywords

CYTOKINE; ECHINACEA PURPUREA EXTRACT; FERRITIN; INTERLEUKIN 1BETA; PLACEBO; PLANT EXTRACT; TUMOR NECROSIS FACTOR ALPHA;

EID: 0036734842     PISSN: 15249557     EISSN: 15374513     Source Type: Journal    
DOI: 10.1097/00002371-200209000-00005     Document Type: Article
Times cited : (38)

References (34)
  • 1
    • 0002527419 scopus 로고
    • Echinacea: a literature review
    • Hobbs C, Echinacea: a literature review. HeralGram 1994; 30:33-48.
    • (1994) HeralGram , vol.30 , pp. 33
    • Hobbs, C.1
  • 2
    • 0033082192 scopus 로고    scopus 로고
    • A randomized controlled trial of the effect of fluid extract of Echinacea purpurea on the incidence severity of colds an respiratory infections
    • Grimm W, Müller HH. A randomized controlled trial of the effect of fluid extract of Echinacea purpurea on the incidence and severity of colds an respiratory infections. Am J Med 1999; 106:138-43.
    • (1999) Am J Med , vol.106 , pp. 138
    • Grimm, W.1    Müller, H.H.2
  • 3
    • 85026175944 scopus 로고    scopus 로고
    • Bauer R, Wagner H. Echinacea Handbuch für Ärzte, Apotheker und andere Naturwissenschaftler. Wissenschaftliche Verlagsgesellschaft mbH, Stuttgart 1990:124-46
    • Bauer R, Wagner H. Echinacea Handbuch für Ärzte, Apotheker und andere Naturwissenschaftler. Wissenschaftliche Verlagsgesellschaft mbH, Stuttgart 1990:124-46.
  • 4
    • 0348099798 scopus 로고    scopus 로고
    • Bauer R. Echinacea: biologic effects and active principles. In: Lawson LD, Bauer R, eds. Phytomedicines of Europe: Chemistry and Biologic Activity. Washington, DC: American Chemists Society, 1998:140-57
    • Bauer R. Echinacea: biologic effects and active principles. In: Lawson LD, Bauer R, eds. Phytomedicines of Europe: Chemistry and Biologic Activity. Washington, DC: American Chemists Society, 1998:140-57.
  • 5
    • 85026172432 scopus 로고
    • Echinacea: Nature's immune enhancer. rochester
    • Foster S. Echinacea: Nature's Immune Enhancer. Rochester, Vermont: Healing Arts Press, 1991.
    • (1991) Vermont: Healing Arts Press
    • Foster, S.1
  • 6
    • 0033175883 scopus 로고    scopus 로고
    • Echinacea for upper respiratory infection
    • Barrett B, Vohmann M, Calabrese C. Echinacea for upper respiratory infection. J Fam Pract 1999; 48:628-35.
    • (1999) J Fam Pract , vol.48 , pp. 628
    • Barrett, B.1    Vohmann, M.2    Calabrese, C.3
  • 7
    • 0029988003 scopus 로고    scopus 로고
    • Clinical application of extracts from Echinacea purpurea or Echinacea pallida. Critical evaluation of controlled clinical studies
    • Dorsch W. Clinical application of extracts from Echinacea purpurea or Echinacea pallida. Critical evaluation of controlled clinical studies. Z Arztl Fortbild Jena 1996; 90:117-22.
    • (1996) Z Arztl Fortbild Jena , vol.90 , pp. 117
    • Dorsch, W.1
  • 8
    • 85026170421 scopus 로고    scopus 로고
    • Parnham MJ. Benefit-risks of the squeezed sap of the purple coneflower (Echinacea purpurea) for long-term oral immunostimulant therapy. In: Wagner H, ed. Immunomodulatory Agents From Plants. Basel: Birkhäuser Verlag 1999:119-35
    • Parnham MJ. Benefit-risks of the squeezed sap of the purple coneflower (Echinacea purpurea) for long-term oral immunostimulant therapy. In: Wagner H, ed. Immunomodulatory Agents From Plants. Basel: Birkhäuser Verlag 1999:119-35.
  • 9
    • 0010412632 scopus 로고    scopus 로고
    • Whole Foods herbal product sales survey
    • Richman A, Witkowski JP. Whole Foods herbal product sales survey. Whole Foods Magazine 1999;22:49-50,52,54,56.
    • (1999) Whole Foods Magazine , vol.22 , pp. 49
    • Richman, A.1    Witkowski, J.P.2
  • 10
    • 0029311850 scopus 로고
    • Results of five randomized studies on the immunomodulatory activity of preparations of Echinacea
    • Melchart A, Linde K, Worku F, et al. Results of five randomized studies on the immunomodulatory activity of preparations of Echinacea. J Alt Compl Med 1995; 1:145-60.
    • (1995) J Alt Compl Med , vol.1 , pp. 145
    • Melchart, A.1    Linde, K.2    Worku, F.3
  • 11
    • 0021716166 scopus 로고
    • Macrophage activation induction of macrophage cytotoxicity by purified polysaccharide fractions from the plant Echinacea purpurea
    • Stimpel H, Proksch A, Wagner H, et al. Macrophage activation and induction of macrophage cytotoxicity by purified polysaccharide fractions from the plant Echinacea purpurea. Infect Immun 1984; 46:845-9.
    • (1984) Infect Immun , vol.46 , pp. 845
    • Stimpel, H.1    Proksch, A.2    Wagner, H.3
  • 12
    • 0024583770 scopus 로고
    • Macrophage activation by the polysaccharide arabinogalactan from the plant cell cultures of Echinacea purpurea
    • Luettig B, Steinmueller C, Gifford GE, et al. Macrophage activation by the polysaccharide arabinogalactan from the plant cell cultures of Echinacea purpurea. J Natl Cancer Inst 1989; 81:669-75.
    • (1989) J Natl Cancer Inst , vol.81 , pp. 669
    • Luettig, B.1    Steinmueller, C.2    Gifford, G.E.3
  • 13
    • 0026001914 scopus 로고
    • Application of purified polysaccharides from cell cultures of the plant Echinacea purpurea to test subjects mediates activation of the phagocyte system
    • Roesler J, Emmendoerfer A, Steinmüller C, et al. Application of purified polysaccharides from cell cultures of the plant Echinacea purpurea to test subjects mediates activation of the phagocyte system. Int J Immunopharma 1991; 13:931-41.
    • (1991) Int J Immunopharma , vol.13 , pp. 931
    • Roesler, J.1    Emmendoerfer, A.2    Steinmüller, C.3
  • 14
    • 0031430958 scopus 로고    scopus 로고
    • Echinacea-induced cytokine production by human macrophages
    • Burger RA, Torres AR, Warren RP, et al. Echinacea-induced cytokine production by human macrophages. Int J Immunopharma 1997; 19:371-9.
    • (1997) Int J Immunopharma , vol.19 , pp. 371
    • Burger, R.A.1    Torres, A.R.2    Warren, R.P.3
  • 15
    • 0030772274 scopus 로고    scopus 로고
    • Normal values for the function of monocytes granulocytes in children
    • Franke L, Pizzulli A. Normal values for the function of monocytes and granulocytes in children. Clin Lab 1997; 43:995-7.
    • (1997) Clin Lab , vol.43 , pp. 995
    • Franke, L.1    Pizzulli, A.2
  • 16
    • 0029646482 scopus 로고
    • Decreased function of monocytes granulocytes during HIV-1 infections correlates with CD4 cell counts
    • Dobmeyer TS, Raffel B, Dobmeyer JM, et al. Decreased function of monocytes and granulocytes during HIV-1 infections correlates with CD4 cell counts. Eur J Med Res 1995; 1:9-15.
    • (1995) Eur J Med Res , vol.1 , pp. 9
    • Dobmeyer, T.S.1    Raffel, B.2    Dobmeyer, J.M.3
  • 17
    • 0343526361 scopus 로고    scopus 로고
    • Influence of the menstrual cycle on the LPS-induced cytokine response of monocytes
    • Schwarz E, Schäfer C, Bode JC, et al. Influence of the menstrual cycle on the LPS-induced cytokine response of monocytes. Cytokine 2000; 12:413-6.
    • (2000) Cytokine , vol.12 , pp. 413
    • Schwarz, E.1    Schäfer, C.2    Bode, J.C.3
  • 18
    • 0029160728 scopus 로고
    • Tumor-necrosis-factor interleukin-6 response of peripheral blood monocytes to low concentrations of lipopolysaccharide in patients with alcoholic liver disease
    • Schäfer C, Schips I, Landig J, et al. Tumor-necrosis-factor and interleukin-6 response of peripheral blood monocytes to low concentrations of lipopolysaccharide in patients with alcoholic liver disease. Z Gastroenterol 1995; 33:503-8.
    • (1995) Z Gastroenterol , vol.33 , pp. 503
    • Schäfer, C.1    Schips, I.2    Landig, J.3
  • 19
    • 0014385564 scopus 로고
    • Isolation of mononuclear cells granulocytes from human blood
    • Boeyum A. Isolation of mononuclear cells and granulocytes from human blood. Scand J Clin Chem Clin Biochem 1968; 97:77-89.
    • (1968) Scand J Clin Chem Clin Biochem , vol.97 , pp. 77
    • Boeyum, A.1
  • 20
    • 0025756921 scopus 로고
    • Analysis of the crossover design in the presence of residual effects
    • Lehmacher W. Analysis of the crossover design in the presence of residual effects. Stat Med 1991; 10:891-9.
    • (1991) Stat Med , vol.10 , pp. 891
    • Lehmacher, W.1
  • 21
    • 85026183794 scopus 로고    scopus 로고
    • Duke JA. The Green Pharmacy. Rodale Press, Emmaus PA, 1997:507
    • Duke JA. The Green Pharmacy. Rodale Press, Emmaus PA, 1997:507.
  • 22
    • 85026172782 scopus 로고
    • Of the bundesgesundheitsamt (German health administration). draft monograph: Echinaceae purpureae herba
    • Commission E of the Bundesgesundheitsamt (German Health Administration). Draft monograph: Echinaceae purpureae herba. Berlin, 1989
    • (1989) Berlin
    • Commission, E.1
  • 23
    • 0010333804 scopus 로고    scopus 로고
    • Echinacea. When should it be used?
    • Bone K. Echinacea. When should it be used? Eur J Herbal Med 1998; 3:77-89.
    • (1998) Eur J Herbal Med , vol.3 , pp. 77
    • Bone, K.1
  • 24
    • 0028322470 scopus 로고
    • Immunomodulation with Echinacea: a systematic review of controlled clinical trials
    • Melchart D, Linde K, Worku F, et al. Immunomodulation with Echinacea: a systematic review of controlled clinical trials. Phytomedicine 1994; 1:245-54.
    • (1994) Phytomedicine , vol.1 , pp. 245
    • Melchart, D.1    Linde, K.2    Worku, F.3
  • 25
    • 0023846108 scopus 로고
    • Immunologic in vivo in vitro studies on Echinacea extracts
    • Bauer R, Jurcic K, Puhlmann J, et al. Immunologic in vivo and in vitro studies on Echinacea extracts. Drug Res 1988; 38:276-81.
    • (1988) Drug Res , vol.38 , pp. 276
    • Bauer, R.1    Jurcic, K.2    Puhlmann, J.3
  • 26
    • 0028212383 scopus 로고
    • The effects of plant preparations on cellular functions in body defense
    • Wildfeuer A, Mayerhofer D. The effects of plant preparations on cellular functions in body defense. Drug Res 1994; 44:361-6.
    • (1994) Drug Res , vol.44 , pp. 361
    • Wildfeuer, A.1    Mayerhofer, D.2
  • 27
    • 0021921260 scopus 로고
    • Effect of a plant immunostimulant on phagocytosis of erythrocytes by the reticulohistiocytary system of isolated perfused rat liver
    • Vömel T. Effect of a plant immunostimulant on phagocytosis of erythrocytes by the reticulohistiocytary system of isolated perfused rat liver. Drug Res 1985; 35:1437-9.
    • (1985) Drug Res , vol.35 , pp. 1437
    • Vömel, T.1
  • 28
    • 0029068373 scopus 로고
    • Immunmodulierende Eigenschaften von Wurzelextrakten verschiedener Echinacea-Arten
    • Beuscher N, Bodinet C, Willigmann I, et al. Immunmodulierende Eigenschaften von Wurzelextrakten verschiedener Echinacea-Arten. Zeitschrift für Phytotherapie. 1995; 16:157-66.
    • (1995) Zeitschrift für Phytotherapie , vol.16 , pp. 157
    • Beuscher, N.1    Bodinet, C.2    Willigmann, I.3
  • 29
    • 0021795584 scopus 로고
    • Evidence from two classic irritation tests for an anti-inflammatory action of a natural extract, Echinacea
    • Tragni E. Evidence from two classic irritation tests for an anti-inflammatory action of a natural extract, Echinacea. Food Chem Toxicol 1985; 23:317-9.
    • (1985) Food Chem Toxicol , vol.23 , pp. 317
    • Tragni, E.1
  • 30
    • 0024788251 scopus 로고
    • In vitro inhibition of arachidonate metabolism by some alkamides acylated phenols
    • Wagner H, Breu W, Willer F. In vitro inhibition of arachidonate metabolism by some alkamides and acylated phenols. Planta Med 1989; 55:566.
    • (1989) Planta Med , vol.55 , pp. 566
    • Wagner, H.1    Breu, W.2    Willer, F.3
  • 31
    • 0004254111 scopus 로고
    • Müeller MD, Algöwer M, Schneider R, Willenegger H, 3rd ed. New York, Springer-Verlag
    • Müeller MD, Algöwer M, Schneider R, Willenegger H: Manual of Internal Fixation, 3rd ed. New York, Springer-Verlag, 1991, p 548
    • (1991) Manual of Internal Fixation , pp. 548
  • 32
    • 0033568442 scopus 로고    scopus 로고
    • Induction of ferritin heat shock proteins by prostaglandin A1 in human monocytes. Evidence for transcriptional post-transcriptional regulation
    • Elia G, Polla B, Rossi A, et al. Induction of ferritin and heat shock proteins by prostaglandin A1 in human monocytes. Evidence for transcriptional and post-transcriptional regulation. Eur J Biochem 1999; 264:736-45.
    • (1999) Eur J Biochem , vol.264 , pp. 736
    • Elia, G.1    Polla, B.2    Rossi, A.3
  • 33
    • 0032800167 scopus 로고    scopus 로고
    • Ferritin correlates with C-reactive protein acute phase amyloid A in synovial fluid, but not in serum
    • Kumon Y, Suehiro T, Nishiya K, et al. Ferritin correlates with C-reactive protein and acute phase amyloid A in synovial fluid, but not in serum. Amyloid 1999; 6:130-5.
    • (1999) Amyloid , vol.6 , pp. 130
    • Kumon, Y.1    Suehiro, T.2    Nishiya, K.3
  • 34
    • 0031454793 scopus 로고    scopus 로고
    • Secretion of ferritin by rat hepatoma cells its regulation by inflammatory cytokines iron
    • Tran TN, Eubank SK, Schaffer KJ, et al. Secretion of ferritin by rat hepatoma cells and its regulation by inflammatory cytokines and iron. Blood 1997; 90:4979-86.
    • (1997) Blood , vol.90 , pp. 4979
    • Tran, T.N.1    Eubank, S.K.2    Schaffer, K.J.3


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