Olanzapine excretion in human breast milk: Estimation of infant exposure

International Journal of Neuropsychopharmacology

Volumn 5, Issue 3, 2002, Pages 243-247

  Croke, Simon ^a   Buist, Anne ^a   Hackett, L Peter ^b   Ilett, Kenneth F ^c   Norman, Trevor R ^a   Burrows, Graham D ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b Western Australian Institute of Medical Research   (Australia)

^c UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Breast milk; Infant; Olanzapine

Indexed keywords

NEUROLEPTIC AGENT; OLANZAPINE;

ADULT; ARTICLE; BREAST FEEDING; BREAST MILK; CALCULATION; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG EXCRETION; DRUG EXPOSURE; DRUG INDUCED DISEASE; DRUG MILK LEVEL; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; INFANT; LACTATION; PRIORITY JOURNAL; PUERPERAL PSYCHOSIS; RISK ASSESSMENT;

ADULT; ANTIPSYCHOTIC AGENTS; BENZODIAZEPINES; DEPRESSION, POSTPARTUM; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; MILK, HUMAN; PIRENZEPINE; PSYCHIATRIC STATUS RATING SCALES;

EID: 0036733299     PISSN: 14611457     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1461145702003012     Document Type: Article

References (27)

1. Aaes-Jorgensen T, Bjorndal F, Bartels U (1996). Zuclopenthixol levels in serum and breast milk. Psychopharmacology 90, 417-418.
2. Agrawal P, Bhatia MS, Malik SC (1997). Post partum psychosis: a clinical study. International Journal of Social Psychiatry 43, 217-222.
3. American Psychiatric Association (1994). Diagnostic and Statistical Manual of Mental Disorders (4th edn). Washington, DC: American Psychiatric Association.
4. Barnas C, Bergant A, Hummer M, Saria A, Fleischhacker WW (1994). Clozapine concentrations in maternal and fetal plasma, amniotic fluid, and breast milk. American Journal of Psychiatry 151, 945.
5. Baselt RC (2000). Olanzapine. In: Disposition of Toxic Drugs and Chemicals in Man (5th edn) (pp. 633-634). Foster City, CA: Chemical Toxicology Institute.
6. Begg EJ, Atkinson HC, Duffull SB (1992). Prospective evaluation of a model for the prediction of milk:plasma drug concentrations from physicochemical characteristics. British Journal of Clinical Pharmacology 33, 501-505.
7. Bennett PN (1996). Use of the monographs in drugs. In: Bennett PN (Ed.), Drugs and Human Lactation (pp. 67-74). Amsterdam: Elsevier Science Publishers.
8. Blacker KH, Weinstein BJ, Ellman GL (1962). Mother's milk and chlorpromazine. American Journal of Psychiatry 119, 178-174.
9. Fulton B, Goa KL (1997). Olanzapine, a review of its pharmacological properties and therapeutic efficacy in the management of schizophrenia and related psychoses. Drugs 53, 281-298.
10. Goodman SH, Brumley HE (1990). Schizophrenic and depressed mothers: relational deficits in parenting. Developmental Psychology 26, 31-39.
11. Hill RC, McIvor R, Wojnar-Horton RE, Hacket LP, Ilett KF (2000). Risperidone distribution and excretion into human milk: a case report and estimated infant exposure during breast-feeding. Journal of Clinical Psychopharmacology 20, 285-286.
12. Kirk L, Jorgensen A (1980). Concentrations of cis(z)flupentixol in maternal serum, amniotic fluid, umbilical cord serum, and milk. Psychopharmacology 72, 107-108.
13. Matheson I, Evang A, Fredricson Overo K, Syversen G (1984). Presence of chlorprothixene and its metabolites in breast milk. European Journal of Clinical Pharmacology 27, 611-613.
14. Matheson I, Skjaeraasen J (1988). Milk concentrations of flupenthixol, nortriptyline and zuclopenthixol and between-breast differences in two patients. European Journal of Clinical Pharmacology 35, 217-220.
15. Miller LJ, Finnerty M (1996). Sexuality, pregnancy, and childrearing among women with schizophrenic-spectrum disorders. Psychiatric Services 47, 502-506.
16. Oates M (1997). Patients as parents: the risk to children. British Journal of Psychiatry 32 (Suppl.), 22-27.
17. Ohkubo T, Shimoyama R, Sugawara K (1992). Measurement of haloperidol in human breast milk by high performance liquid chromatography. Journal of Pharmaceutical Sciences 81, 947-949.
18. Olesen OV, Bartels U, Poulsen JH (1990). Perphenazine in breast milk and serum. American Journal of Psychiatry 147, 1378-1379.
19. Perry PJ, Sanger T, Beasley C (1997). Olanzapine plasma concentrations and clinical response in acutely ill schizophrenic patients. Journal of Clinical Psychopharmacology 17, 472-477.
20. Pritchard DB, Harris B (1996). Aspects of perinatal psychiatric illness. British Journal of Psychiatry 169, 555-562.
21. Rampono J, Kristensen JH, Hackett LP, Paech M, Kohan R, Ilett KF (2000). Citalopram and demethylcitalopram in human milk: distribution, excretion and effects in breast fed infants. British Journal of Clinical Pharmacology 50, 263-268.
22. Stephenson CME, Pilowsky LS (1999). Psychopharmacology of olanzapine, a review. British Journal of Psychiatry 174 (Suppl. 38), 52-58.
23. Stewart RB, Karas B, Springer PK (1980). Haloperidol excretion in human milk. American Journal of Psychiatry 137, 849-850.
24. Tollefson GD, Beasley CM, Tran PV, Street JS, Krueger JA, Tamura RN, Graffeo KA, Thieme ME (1997). Olanzapine versus haloperidol in the treatment of schizophrenia and schizoaffective and schizophreniform disorders: results of an international collaborative trial. American Journal of Psychiatry 154, 457-465.
25. Whalley LJ, Blain PG, Prime JK (1981). Haloperidol secreted in breast milk. British Medical Journal 282, 1746-1747.
26. Wiles DH, Orr MW, Kolakowska T (1978). Chlorpromazine levels in plasma and milk of nursing mothers. British Journal of Clinical Pharmacology 5, 272-273.
27. Yoshida K, Smith B, Craggs M, Kumar R (1998). Neuroleptic drugs in breast-milk: a study of pharmacokinetics and of possible adverse effects in breast-fed infants. Psychological Medicine 28, 81-91.