Fibroblast growth factor signaling regulates Dach1 expression during skeletal development

Developmental Dynamics

Volumn 225, Issue 1, 2002, Pages 35-45

  Horner, A ^a   Shum, L ^a   Ayres, J A ^a   Nonaka, K ^a   Nuckolls, G H ^a  

^a NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

Author keywords

Cell cycle; Endochondral ossification; Growth plate; Limb bud; Patterning; Transcription factor

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; BOVINE SERUM ALBUMIN; BROXURIDINE; CYCLIN DEPENDENT KINASE INHIBITOR; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR RECEPTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR 3; HEPARAN SULFATE; NUCLEAR PROTEIN; PROTEIN DACH1; PROTEIN P27; PROTEIN P57; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; CARTILAGE CELL; CELL DIFFERENTIATION; CELL FATE; CELL PROLIFERATION; CONTROLLED STUDY; EMBRYO; ENCHONDRAL OSSIFICATION; EPIPHYSIS; FEMALE; FETUS; GENE EXPRESSION REGULATION; GROWTH PLATE; IN SITU HYBRIDIZATION; LIMB BUD; LIMB DEVELOPMENT; MESENCHYME; MOUSE; NEWBORN; NONHUMAN; OSSIFICATION; POSTNATAL DEVELOPMENT; PRENATAL DEVELOPMENT; PRIORITY JOURNAL;

ANIMALS; BODY PATTERNING; BONE DEVELOPMENT; CELL CYCLE PROTEINS; CELL DIFFERENTIATION; CELL DIVISION; CHONDROCYTES; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLIN-DEPENDENT KINASE INHIBITOR P57; EXTREMITIES; EYE PROTEINS; FIBROBLAST GROWTH FACTORS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MICE; NUCLEAR PROTEINS; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS;

ANIMALIA; BOVINAE; ERINACEIDAE;

EID: 0036731803     PISSN: 10588388     EISSN: None     Source Type: Journal    
DOI: 10.1002/dvdy.10132     Document Type: Article

References (61)

1. Fibroblast growth factor inhibits chondrocytic growth through induction of p21 and subsequent inactivation of cyclin E-Cdk2
2. DACH: Genomic characterization, evaluation as a candidate for postaxial polydactyly type A2, and developmental expression pattern of the mouse homologue
3. Patterning mechanisms controlling vertebrate limb development
4. Mouse Dac, a novel nuclear factor with homology to Drosophila dachshund shows a dynamic expression in the neural crest, the eye, the neocortex, and the limb bud
5. Vertebrate orthologues of the Drosophila region-specific patterning gene teashirt
6. Dachshund and eyes absent proteins form a complex and function synergistically to induce ectopic eye development in Drosophila
7. Signaling by the TGF-b homolog decapentaplegic functions reiteratively within the network of genes controlling retinal cell fate determination in Drosophila
8. Roles for FGF8 in the induction, initiation, and maintenance of chick limb development
9. Morphogenetic furrow initiation and progression during eye development in Drosophila: The roles of decapentaplegic, hedgehog and eyes absent
10. Limiting outgrowth: BMPs as negative regulators in limb development
11. Mouse Dach, a homologue of Drosophila dachshund, is expressed in the developing retina, brain and limbs
12. Dach1 mutant mice bear no gross abnormalities in eye, limb, and brain development and exhibit postnatal lethality
13. Characterization of mouse Dach2, a homologue of Drosophila dachshund
14. Improved methodology for detecting bromodeoxyuridine in cultured cells and tissue sections by immunocytochemistry
15. Mammalian and Drosophila dachshund genes are related to the Ski proto-oncogene and are expressed in eye and limb
16. Isolation of three zebrafish dachshund homologues and their expression in sensory organs, the central nervous system and pectoral fin buds
17. Synergistic regulation of vertebrate muscle development by Dach2, Eya2 and Six1, homologues of genes required for Drosophila eye formation
18. Dach1, a vertebrate homologue of Drosophila dachshund, is expressed in the developing eye and ear of both chick and mouse and is regulated independently of Pax and Eya genes
19. Expression and distribution of transforming growth factor-beta isoforms and their signaling receptors in growing human bone
20. Stimulation of embryonic limb bud mesenchymal cell growth by peptide growth factors
21. The Drosophila sex determination hierarchy modulates wingless and decapentaplegic signaling to deploy dachshund sex-specifically in the genital imaginal disc
22. Regulation of chondrocyte differentiation by Cbfa1
23. Targeted disruption of Cbfal results in a complete lack of bone formation owing to maturational arrest of osteoblasts
24. Molecular cloning and expression of the human and mouse homologues of the Drosophila dachshund gene
25. Expression of the paired-box genes Pax-1 and Pax-9 in limb skeleton development
26. Proximal-distal axis formation in Drosophila leg
27. Expression and regulation of mouse Mtsh1 during limb and branchial arch development
28. Cloning and expression of medaka dachshund
29. The mUBC9 murine ubiquitin conjugating enzyme interacts with the E2A transcription factors
30. Yeast two-hybrid system identifies the ubiquitin-conjugating enzyme mUbc9 as a potential partner of mouse Dac
31. Dachshund encodes a nuclear protein required for normal eye and leg development in Drosophila
32. The roles of FGFs in the early development of vertebrate limbs
33. The retinal determination gene, dachshund, is required for mushroom body cell differentiation
34. Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia
35. Spatial and temporal expression patterns of the cyclin-dependent kinase (CDK) inhibitors p27Kip1 and p57Kip2 during mouse development
36. FGF-4 replaces the apical ectodermal ridge and directs out growth and patterning of the limb
37. Bone development
38. Regulation of chondrocyte growth and differentiation by fibroblast growth factor receptor 3
39. Receptor specificity of the fibroblast growth factor family
40. Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development
41. Impaired interactions between mouse Eya1 harbouring mutations found in patients with branchio-oto-renal syndrome and Six, Dac, and G proteins
42. Targeted expression of teashirt induces ectopic eyes in Drosophila
43. FGF signaling inhibits chondrocyte proliferation and regulates bone development through the STAT-1 pathway
44. Positionally-dependent chondrogenesis is induced by BR is co-regulated by Sox9 and Msx2
45. Role of a ubiquitin-conjugating enzyme in degradation of S-and M-phase cyclins
46. Ectopic eye development in Drosophila induced by directed dachshund expression
47. The life cycle of chondrocytes in the developing skeleton
48. Expression of p21CIP1/WAF1 in chondrocytes
49. Activation of Stat1 by mutant fibroblast growth-factor receptor in thanatophoric dysplasia type II dwarfism
50. Control of cell cycle gene expression in bone development and during c-Fos-induced osteosarcoma formation
51. Changes in the expression of fibroblast growth factor receptors mark distinct stages of chondrogenesis in vitro and during chick limb skeletal patterning
52. Continuous expression of Cbfa1 in nonhypertrophic chondrocytes uncovers its ability to induce hypertrophic chondrocyte differentiation and partially rescues Cbfa1-deficient mice
53. Vertebrate limb development - The early stages in chick and mouse
54. Skeletal malformations caused by overexpression of Cbfa1 or its dominant negative form in chondrocytes
55. FGF-4 maintains polarizing activity of posterior limb bud cells in vivo and in vitro
56. Involvement of FGF-8 in initiation, outgrowth and patterning of the vertebrate limb
57. Interaction of growth factors regulating chondrocyte differentiation in the developing embryo
58. Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction
59. Fibroblast growth factor receptors (FGFRs) and their roles in limb development
60. Altered cell differentiation and proliferation in mice lacking p57KIP2 indicates a role in Beckwith-Wiedeman syndrome
61. A pro250Arg substitution in mouse Fgfr1 causes increased expression of Cbfa1 and premature fusion of calvarial sutures