Inhibition of 3α/β,20β-hydroxysteroid dehydrogenase by dexamethasone, glycyrrhetinic acid and spironolactone is attenuated by deletion of 12 carboxyl-terminal residues

Biological and Pharmaceutical Bulletin

Volumn 25, Issue 9, 2002, Pages 1220-1222

  Itoda, Masaya ^a   Takase, Noriko ^a   Nakajin, Shizuo ^a  

^a HOSHI UNIVERSITY   (Japan)

Author keywords

Hydroxysteroid dehydrogenase; Inhibition; Short chain dehydrogenase reductase

Indexed keywords

DEXAMETHASONE; GLYCYRRHETINIC ACID; HYDROXYSTEROID DEHYDROGENASE; SPIRONOLACTONE; 3 ALPHA BETA, 20 BETA HYDROXYSTEROID DEHYDROGENASE; 3 ALPHA-BETA, 20 BETA-HYDROXYSTEROID DEHYDROGENASE; 3ALPHA(OR 20BETA) HYDROXYSTEROID DEHYDROGENASE; AMINO ACID; ENZYME INHIBITOR; PEPTIDE FRAGMENT;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE DELETION; NONHUMAN; RNA TRANSLATION; STEROID METABOLISM; ANIMAL; COMPARATIVE STUDY; DRUG ANTAGONISM; DRUG EFFECT; ENZYME ACTIVATION; GENETICS; METABOLISM; RAT; SITE DIRECTED MUTAGENESIS; SWINE;

20-HYDROXYSTEROID DEHYDROGENASES; AMINO ACIDS; ANIMALS; DEXAMETHASONE; ENZYME ACTIVATION; ENZYME INHIBITORS; GLYCYRRHETINIC ACID; MUTAGENESIS, SITE-DIRECTED; PEPTIDE FRAGMENTS; RATS; SPIRONOLACTONE; SWINE;

EID: 0036731398     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.25.1220     Document Type: Article

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