Calcium-independent phospholipase A2-derived arachidonic acid is essential for endothelium-dependent relaxation by acetylcholine

Journal of Pharmacology and Experimental Therapeutics

Volumn 302, Issue 3, 2002, Pages 918-923

  Seegers, Hélène C ^a,c   Gross, Richard W ^b,d   Boyle, Walter A ^a  

^a Department of Anesthesiology ^*  (United Kingdom)

^b WASHINGTON UNIVERSITY   (United States)

^c UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^d WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

17 OCTADECYNOIC ACID; ACETYLCHOLINE; ARACHIDONIC ACID; ARACHIDONIC ACID DERIVATIVE; ARACHIDONIC ACID METHYL ESTER; CALCIUM; CYTOCHROME P450 INHIBITOR; CYTOCHROME P450 MONOOXYGENASE INHIBITOR; DELTA BROMOMETHYLENE ALPHA (1 NAPHTHYL) DELTA VALEROLACTONE; ESCULETIN; INDOMETACIN; LIPOXYGENASE INHIBITOR; N(G) NITROARGININE; NITRIC OXIDE SYNTHASE INHIBITOR; PHENYLEPHRINE; PHOSPHOLIPASE A2; PHOSPHOLIPASE A2 INHIBITOR; PROSTAGLANDIN SYNTHASE INHIBITOR; UNCLASSIFIED DRUG;

ACETYLCHOLINE RELEASE; ANIMAL CELL; ANIMAL TISSUE; ARACHIDONIC ACID METABOLISM; ARTICLE; BINDING KINETICS; CALCIUM TRANSPORT; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME BINDING; ENZYME INHIBITION; INHIBITION KINETICS; MESENTERIC ARTERY; NONHUMAN; PRIORITY JOURNAL; RAT; RESISTANCE BLOOD VESSEL; VASODILATATION;

ACETYLCHOLINE; ANIMALS; ARACHIDONIC ACID; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; FATTY ACIDS; MALE; MUSCLE CONTRACTION; MUSCLE RELAXATION; MUSCLE, SMOOTH, VASCULAR; NITRIC OXIDE; PHOSPHOLIPASES A; RATS; RATS, SPRAGUE-DAWLEY; VASODILATOR AGENTS;

EID: 0036721414     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.302.3.918     Document Type: Article

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