Sexual dimorphic expression of ADH in rat liver: Importance of the hypothalamic-pituitary-liver axis

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 283, Issue 3 46-3, 2002, Pages

  Simon, Francis R ^a,b   Fortune, John ^a,b   Iwahashi, Mieko ^a,b   Sutherland, Eileen ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

Estrogen; Growth hormone; Hypophysectomy; Testosterone; Thyroxine

Indexed keywords

ALCOHOL; ALCOHOL DEHYDROGENASE; ESTRADIOL; GROWTH HORMONE; MESSENGER RNA; TESTOSTERONE; THYROXINE;

ALCOHOL METABOLISM; ALCOHOL OXIDATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GONADECTOMY; GROWTH HORMONE RELEASE; HORMONAL REGULATION; HYPOPHYSECTOMY; HYPOTHALAMUS HYPOPHYSIS SYSTEM; LIVER METABOLISM; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; RAT; RNA ANALYSIS; SEX DIFFERENCE; WEIGHT GAIN;

EID: 0036720949     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.00438.2001     Document Type: Article

References (63)

1. Purification and molecular properties of mouse alcohol dehydrogenase isozymes
2. Alcohol dehydrogenase isoenzymes in rat development. Effect of maternal ethanol consumption
3. Effect of fasting on the activity and turnover of rat liver alcohol dehydrogenase
4. Aldehyd- und alkoholdehydrogenase-aktivitat in leber und niere der ratte
5. Plasma growth hormone pulse activation of hepatic JAK-STAT5 signaling: Developmental regulation and role in male-specific liver gene expression
6. Intravenous growth hormone: Growth responses to patterned infusions in hypophysectomized rats
7. Effect of hypothyroidism and thyroxine replacement on growth hormone in the rat
8. Ethanol oxidizing enzymes: Roles in alcohol metabolism and alcoholic liver disease
9. Role of the pituitary and neonatal androgenic imprinting in the hormonal regulation of liver alcohol dehydrogenase activity
10. Loss of growth hormone-dependent characteristics of rat hepatocytes in culture
11. Regulation of rates of ethanol metabolism
12. STAT5b-deficient mice are growth hormone pulse-resistant. Role of STAT5b in sex-specific liver P450 expression
13. Synergistic action of hepatocyte nuclear factors 3 and 6 on CYP2C12 gene expression and suppression by growth hormone-activated STAT5b. Proposed model for female specific expression of CYP2C12 in adult rat liver
14. Effects of thyroxine on the expression of alcohol dehydrogenase in rat liver and kidney
15. Age- and sex-related differences in episodic growth hormone secretion in the rat
16. Alcohol dehydrogenases: Molecular biology and gene regulation
17. Cross-talk between signal transducer and activator of transcription (Stat5) and thyroid hormone receptor-beta 1 (TRbeta1) signaling pathways
18. The aversive and hypophagic effects of estradiol
19. Growth hormone: A regulator of the sexually differentiated steroid metabolism in rat liver
20. Sex steroid induced changes in hepatic enzymes
21. Sex change in cytochrome P-450 phenotype by growth hormone treatment of adult rat hepatocytes maintained in a culture system on matrigel
22. The multifaceted mechanisms of estradiol and estrogen receptor signaling
23. Retinoic acid activation and thyroid hormone repression of the human alcohol dehydrogenase gene ADH3
24. Tissue and development specific regulation of a complex family of rat insulin-like growth factor I messenger ribonucleic acids
25. Sexual dimorphism in the control of growth hormone secretion
26. Imprinting of growth hormone secretion, body growth, and hepatic steroid metabolism by neonatal testosterone
27. Influence of gonadal steroids on age- and sex-related secretory patterns of growth hormone in the rat
28. Roles of hormonal and nutritional factors in the regulation of rat liver alcohol dehydrogenase activity and ethanol elimination rate in vivo
29. Hepatic steroid hydroxylating enzymes are controlled by the sexually dimorphic pattern of growth hormone secretion in normal and dwarf rats
30. Transcriptional regulation of rat P-450 2C gene subfamily members by the sexually dimorphic pattern of growth hormone secretion
31. Cytochrome P-4502E1: Its physiological and pathological role
32. Subcellular distribution and kinetic parameters of HS mouse liver aldehyde dehydrogenase
33. Protein measurement with the Folin phenol reagent
34. Quantitative correlation of ethanol elimination rates in vivo with liver alcohol dehydrogenase activities in fed, fasted and food-restricted rats
35. Regulation of insulin-like growth factor I gene expression by growth hormone
36. Hormonal regulation of male-specific rat hepatic cytochrome P-450g (P-450IIC13) by androgens and the pituitary
37. Influence of sex hormones on alcohol metabolism
38. Effect of castration on the turnover of rat liver alcohol dehydrogenase
39. Effects of thyroidectomy and triiodothyronine administration on rat liver alcohol dehydrogenase
40. Rat liver alcohol dehydrogenase activity: Effects of growth hormone and hypophysectomy
41. Effects of castration and testosterone administration on rat liver alcohol dehydrogenase activity
42. Liver alcohol dehydrogenase activity in the female rat: Effects of ovariectomy and estradiol administration
43. Hormonal regulation of the rat class I alcohol dehydrogenase gene
44. Effect of dihydrotestosterone on turnover of alcohol dehydrogenase in rat hepatocyte culture
45. A dual role of growth hormone as a feminizing and masculinizing factor in the control of sex-specific cytochrome P-450 isozymes in rat liver
46. Endogenous testosterone enhances growth hormone (GH)-releasing factor-induced GH secretion in vitro
47. Pulsatile growth hormone secretion decreases S-adenosylmethionine synthetase in rat liver
48. Renaturalizing the sexually dimorphic profiles of circulating growth hormone in hypophysectomized rats
49. Effect of STAT5b on rat liver alcohol dehydrogenase
50. Influence of growth hormone on the synthesis of rat liver alcohol dehydrogenase in primary hepatocyte culture
51. Estradiol regulates class I alcohol dehydrogenase gene expression in renal medulla of male rats by a post-transcriptional mechanism
52. Sex differences in hepatic alcohol dehydrogenase activity in animal species
53. Modulation of alcohol dehydrogenase and ethanol metabolism by sex hormones in the spontaneously hypertensive rat. Effect of chronic ethanol administration
54. Thyroid hormone stimulation of NADPH P450 reductase expression in liver and extrahepatic tissues. Regulation by multiple mechanisms
55. Sexual dimorphism in the liver
56. Increased hepatic Na,K-ATPase activity during hepatic regeneration is associated with induction of the betal-subunit and expression on the bile canalicular domain
57. Sex-specific, growth hormone-regulated transcription of the cytochrome P450 2C11 and 2C12 genes
58. Effect of sex hormones on the activities of hepatic alcohol-metabolizing enzymes in male rats
59. Sex-dependency of hepatic alcohol metabolizing enzymes
60. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
61. Sex hormones and the selective estrogen receptor modulator tamoxifen modulate weekly body weights and food intakes in adolescent and adult rats
62. Growth hormone pulse-activated STAT5 signalling: A unique regulatory mechanism governing sexual dimorphism of liver gene expression
63. Feedback regulation of growth hormone secretion