Dose escalation using twice-daily radiotherapy for nasopharyngeal carcinoma: Does heavier dosing result in a happier ending?

International Journal of Radiation Oncology Biology Physics

Volumn 54, Issue 1, 2002, Pages 14-22

  Jen, Yee Min ^a   Lin, Yaoh Shiang ^a   Su, Wan Fu ^a   Hsu, Wen Lin ^a   Hwang, Jing Min ^a   Chao, Hsing Lung ^a   Liu, Dai Wei ^a   Chen, Chang Ming ^a   Lin, Hon Yi ^a   Wu, Ching Jung ^b   Chang, Li Ping ^a   Shueng, Pei Wei ^a,c  

^a TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^b CATHAY GENERAL HOSPITAL   (Taiwan)

^c FAR EASTERN MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Altered fractionation; Nasopharyngeal neoplasms; Radiotherapy

Indexed keywords

PATIENT TREATMENT; RADIOTHERAPY;

DOSE ESCALATION;

ONCOLOGY;

ADOLESCENT; ADULT; AGED; ARTICLE; BRAIN NECROSIS; CANCER RADIOTHERAPY; CANCER STAGING; CONTROLLED STUDY; DESQUAMATION; FEMALE; FIBROSIS; FOLLOW UP; HUMAN; INCIDENCE; LEUKOPENIA; MAJOR CLINICAL STUDY; MALE; MUCOSA INFLAMMATION; NASOPHARYNX CARCINOMA; NAUSEA; OTITIS MEDIA; PRIORITY JOURNAL; RADIATION DOSE; RADIATION INJURY; TEMPORAL LOBE; TREATMENT FAILURE; TRISMUS; VOMITING; WEIGHT REDUCTION; XEROSTOMIA;

ADOLESCENT; ADULT; AGED; DOSE FRACTIONATION; FEMALE; HUMANS; MALE; MIDDLE AGED; NASOPHARYNGEAL NEOPLASMS; RADIOTHERAPY; RADIOTHERAPY DOSAGE; TREATMENT FAILURE;

EID: 0036719947     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0360-3016(02)02914-0     Document Type: Article

References (26)

1. Nasopharyngeal cancer: Study III. A review of 1206 patients treated with combined modalities
2. Nasopharyngeal cancer: Epidemiology, staging, and treatment
3. Impact of changes in the treatment of nasopharyngeal carcinoma: An experience of 30 years
4. Comparison of continuous and split-course radiotherapy for nasopharyngeal carcinoma - An analysis of 1446 cases with squamous cell carcinoma grade 3
5. Dose fractionation, dose rate and iso-effect relationships for normal tissue responses
6. The linear-quadratic formula and progress in fractionated radiotherapy
7. Dose-fractionation sensitivity of mouse kidney clonogens measured using different interfraction intervals and postirradiation assay times
8. Changes in early and late radiation responses with altered dose fractionation: Implications for dose-survival relationships
9. Fractionation parameters for human tissues and tumors
10. Dose-response for local control with hyperfractionated radiation therapy in advanced carcinomas of the upper aerodigestive tracts: Preliminary report of Radiation Therapy Oncology Group protocol 83-13
11. Accelerated hyperfractionation radiation therapy for carcinoma of the nasopharynx: Techniques and results
12. Different risks of symptomatic brain necrosis in NPC patients treated with different altered fractionated radiotherapy techniques
13. Hyperfractionated photon radiation therapy in the treatment of advanced squamous cell carcinoma of the oral cavity, pharynx, larynx, and sinuses, using radiation therapy as the only planned modality: Preliminary report by the Radiation Therapy Oncology Group (RTOG)
14. Hyperfractionated radiotherapy in the treatment of squamous cell carcinomas of the supraglottic larynx
15. Hyperfractionation versus conventional fractionation in oropharyngeal carcinoma: Final analysis of a randomized trial of the EORTC cooperative group of radiotherapy
16. Late effects of hyperfractionated radiotherapy for advanced head and neck cancer: Long-term follow-up results of RTOG 83-13
17. Early tumour response and treatment toxicity after hyperfractionated radiotherapy in nasopharyngeal carcinoma
18. Concomitant infusion cisplatin and hyperfractionated radiotherapy for locally advanced nasopharyngeal and paranasal sinus tumors
19. Hyperfractionated radiotherapy followed by adjuvant chemotherapy for nasopharyngeal cancer: Report of seven cases
20. Accelerated treatment and radiation myelitis
21. Caution on the use of altered fractionation for nasopharyngeal carcinoma
22. Accelerated fractionation (AF) compared to conventional fractionation (CF) improves loco-regional control in the radiotherapy of advanced head, and neck cancers: Results of the EORTC 22851 randomized trial
23. A randomized trial of accelerated versus conventional radiotherapy in head and neck cancers
24. Statistical power and sample size calculation
25. A phase II study of paclitaxel, carboplatin, and hyperfractionated radiation therapy for locally advanced inoperable non-small-cell lung cancer (a Vanderbilt Cancer Center Affiliate Network Study)
26. Influence of interfraction interval on the efficacy and toxicity of hyperfractionated radiotherapy in combination with concurrent daily chemotherapy in stage III non-small-cell lung cancer