Growth control of C6 glioma in vivo by nerve growth factor

Journal of Neuro-Oncology

Volumn 59, Issue 3, 2002, Pages 199-205

  Kimura, Shigeyoshi ^a   Yoshino, Atsuo ^a   Katayama, Yoichi ^a   Watanabe, Takao ^a   Fukushima, Takao ^a  

^a NIHON UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

C6 glioma; Glycolysis; NGF; Oxidative phosphorylation; Proliferation

Indexed keywords

CYTOCHROME C OXIDASE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; HEXOKINASE; MONOCLONAL ANTIBODY KI 67; NERVE GROWTH FACTOR BETA SUBUNIT; NERVE GROWTH FACTOR RECEPTOR; PENTOSE PHOSPHATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CELL DIFFERENTIATION; CONTROLLED STUDY; CORPUS STRIATUM; CORRELATION ANALYSIS; ENERGY METABOLISM; ENZYME ACTIVITY; ENZYME HISTOCHEMISTRY; GLIOMA; GLYCOLYSIS; GROWTH REGULATION; IMMUNOREACTIVITY; IN VIVO STUDY; MALE; NONHUMAN; RAT; TUMOR VOLUME; TUMOR XENOGRAFT;

ANIMALS; BRAIN NEOPLASMS; CELL DIFFERENTIATION; CELL DIVISION; GLIOMA; GLUCOSEPHOSPHATE DEHYDROGENASE; HEXOKINASE; IMMUNOENZYME TECHNIQUES; KI-67 ANTIGEN; MALE; NEOPLASM TRANSPLANTATION; NERVE GROWTH FACTORS; PENTOSE PHOSPHATE PATHWAY; RATS; RATS, WISTAR; TUMOR CELLS, CULTURED;

EID: 0036715149     PISSN: 0167594X     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1019919019497     Document Type: Article

References (51)

1. Nerve growth factor
2. Establishment of a noradrenergic clonal line of rat adrenal phenochromocytoma cells which respond to nerve growth factor
3. Nerve growth factor-induced fiber outgrowth from isolated rat adrenal chromaffin cells: Impairment by glucocorticoids
4. Environmental influence in the development of neural crest derivatives: Glucocorticoids, growth factors and chromaffin cell plasticity
5. Nerve growth factor is a mitogen for cultured chromaffin cells
6. Development regulation of nerve growth factor and its receptor in the rat caudate putamen
7. Proliferation and differentiation of neuronal stem cells regulated by nerve growth factor
8. Nerve growth factor is a potent inducer of proliferation and neuronal differentiation for adult rat chromaffin cells in vitro
9. Regulation of TrkA and ChAT expression in developing rat basal forebrain: Evidence that both exogenous and endogenous NGF regulate differentiation of cholinergic neurons
10. The trk family of neurotrophin receptors
11. NGF ligand alters NGF signaling via p75NTR and TrkA
12. Competitive signaling between TrkA and p75 nerve growth factor receptors determines cell survival
13. p75 nerve growth factor receptor modulates p140trkA kinase activity, but not ligand internalization, in PC12 cells
14. Reciprocal modulation of TrkA and p75NTR affinity states is mediated by direct receptor interactions
15. Characterization of functional nerve growth factor-receptors in a CNS glial cell line: Monoclonal antibody 217c recognizes the nerve growth factor-receptor on C6 glioma cells
16. Characterization and growth-dependent regulation of the nerve growth factor receptor gp140trk in rat C6 glioma cells
17. Control of proliferation and survival of C6 glioma cells with modification of the nerve growth factor autocrine system
18. Engraftment of C6-2B cells into the striatum of ACI nude rats as a tool for comparison of the in vitro and in vivo phenotype of a glioma cell line
19. Differentiation and growth inhibition of glioma cells induced by transfer of Trk A proto-oncogene
20. Dorsal root ganglion neurons are destroyed by exposure in utero to maternal antibody to nerve growth factor
21. Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation
22. Temporal analysis of events associated with programmed cell death (apoptosis) of sympathetic neurons deprived of nerve growth factor
23. A system for characterizing cellular and molecular events in programmed neuronal cell death
24. Analysis of cell cycle-related gene expression in postmitotic neurons: Selective induction of cyclin D1 during programmed cell death
25. Nerve growth factor induces apoptosis in human medulloblastoma cell lines that express TrkA receptors
26. Neurotrophins and neuronal versus glial differentiation in medulloblastomas and other pediatric brain tumors
27. A novel apoptotic pathway induced by nerve growth factor-mediated TrkA activation in medulloblastoma
28. Enzymes of glucose metabolism in cultured human gliomas: Neoplasia is accompanied by altered hexokinase levels
29. Histochemical evaluation of energy metabolism in rat glioma
30. Histochemical and immunohistochemical localization of hexokinase isoenzymes in rat kidney
31. Enzyme histochemistry
32. Cytochrome oxidase: An endogenous metabolic marker for neuronal activity
33. 14C] cyanide tissue labeling in vivo
34. Transplantation of tumors of the nervous system, induced by resorptive carcinogens. 1. Histological investigation of intracerebrally transplanted tumors of the central nervous system
35. Experimental brain tumors and edema in rats: 1. Histology and cytology of tumors
36. NGF-mediated increase of choline acetyltransferase (ChAT) in the neonatal rat forebrain: Evidence for a physiological role of NGF in the brain?
37. Chronic intraventricular injections of nerve growth factor elevate hippocampal choline acetyltransferase activity in adult rats with partial septo-hippocampal lesions
38. Continuous infusion of nerve growth factor prevents basal forebrain neuronal death after fimbria fornix transection
39. Nerve growth factor treatment after brain injury prevents neuronal death
40. Morphological response of axotomized septal neurons to nerve growth factor
41. On the origin of cancer cells
42. High aerobic glycolysis of rat hepatoma cells in culture: Role of mitochondrial hexokinase
43. Tumor mitochondria and the bioenergetics of cancer cells
44. Oxidative metabolism of brain tumors
45. 18F]-fluorodeoxyglucose and positron emission tomography
46. Correlation of experimental and clinical studies of metabolism by PET scanning
47. Oxidative metabolism and glycolysis in benign brain tumors
48. Modulation of glycolysis in neuroepithelial tumors
49. Metabolic patterns in malignant gliomas
50. Diversity of metabolic patterns in human brain tumors: Enzymes of energy metabolism and related metabolites and cofactors
51. Gliomas are driven by glycolysis: Putative roles of hexokinase, oxidative phosphorylation and mitochondrial ultrastructure