In vivo receptor assay with multiple ligand concentrations: An equilibrium approach

Journal of Cerebral Blood Flow and Metabolism

Volumn 22, Issue 9, 2002, Pages 1132-1141

  Holden, James E ^a   Jivan, Salma ^a   Ruth, Thomas J ^a   Doudet, Doris J ^a  

^a 1530 Medical Sciences Center ^*  (United States)

Author keywords

D2 receptors; MPTP treated monkeys; Raclopride

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; RACLOPRIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOPAMINERGIC SYSTEM; EQUILIBRIUM CONSTANT; IN VIVO STUDY; LIGAND BINDING; MALE; MONKEY; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RECEPTOR BINDING; RECEPTOR DENSITY;

EID: 0036714078     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004647-200209000-00011     Document Type: Article

References (28)

1. 11C-raclopride and positron emission tomography
2. 8F]cyclofoxy and positron emission tomography
3. 11C]raclopride binding with continuous infusion
4. 11C]flumazenil and a single experiment protocol
5. Concept of reaction volume in the in vivo ligand-receptor model
6. 2 receptors using a high-affinity ligand (FLB 457) and the multiinjection approach
7. Absolute quantification by positron emission tomography of the endogenous ligand
8. 2 receptors in rhesus monkeys with long-term MPTP-induced parkinsonism
9. 2 receptor density in MPTP monkeys
10. 2-dopamine receptors studied by PET: A comparison to the equilibrium analysis
11. Subdivisional involvement of the nigrostriatal loop in idiopathic Parkinson's disease and striatonigral degeneration
12. 2 values in graphical estimation of DV ratios of reversible ligands
13. Positron emission tomography of radioligand binding in porcine striatum in vivo: Haloperidol inhibition linked to endogenous ligand release
14. 11C]raclopride binding
15. 11C]methane
16. Imaging synaptic neurotransmission with in vivo binding competition techniques: A critical review
17. 123I]iomazenil binding to benzodiazepine receptors in nonhuman primates. Part II: Equilibrium analysis of constant infusion experiments and correlation with in vitro parameters
18. 2
19. Distribution volume ratios without blood sampling from graphical analysis of PET data
20. A quantitative model for the in vivo assessment of drug binding sites with positron emission tomography
21. 18F]fluoro-L-dopa
22. 11C]raclopride
23. 2 receptor supersensitivity in the striatum of patients with early Parkinson's disease
24. The attractions of proteins for small molecules and ions
25. 3H]spiperone depend on tissue concentration: Analysis and examples
26. Effects of statistical noise on graphical analysis of PET neuroreceptor studies
27. Identifiability analysis of an in vivo receptor binding using positron emission tomography
28. Development of haloperidol-induced dopamine release in the rat striatum using intracerebral dialysis