A complex DNA-repeat structure within the Selenoprotein P promoter contains a functionally relevant polymorphism and is genetically unstable under conditions of mismatch repair deficiency

European Journal of Human Genetics

Volumn 10, Issue 9, 2002, Pages 499-504

  Al Taie, Oliver H ^a   Seufert, Jochen ^a   Mörk, Hubert ^a,d   Treis, Holger ^a   Mentrup, Birgit ^a   Thalheimer, Andreas ^b   Starostik, Petr ^b   Abel, Josef ^c   Scheurlen, Michael ^a   Köhrle, Josef ^a   Jakob, Franz ^a  

^a UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c HEINRICH HEINE UNIVERSITY   (Germany)

^d Kreiskrankenhaus Nagold ^*  (Germany)

Author keywords

Colorectal cancer; DNA repeat; Genomic instability; Polymorphism; Promoter; Selenoprotein P

Indexed keywords

ADENINE; CYTOKINE; CYTOSINE; GAMMA INTERFERON; GENOMIC DNA; GLYCOPROTEIN; GUANINE; INTERLEUKIN 1BETA; REPETITIVE DNA; SELENIUM; SELENOPROTEIN; THYMINE; TRANSFORMING GROWTH FACTOR BETA;

ALLELE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BASE PAIRING; CELL STRAIN HEPG2; COLON ADENOMA; COLON CANCER; COLON CARCINOMA; COLORECTAL CANCER; CONTROLLED STUDY; DNA DETERMINATION; DNA POLYMORPHISM; DNA SEQUENCE; DNA STRUCTURE; DRUG EFFECT; GASTROINTESTINAL TRACT; GENE EXPRESSION; GENETIC STABILITY; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; HUMAN TISSUE; LIVER; MISMATCH REPAIR; NUCLEOTIDE REPEAT; NUCLEOTIDE SEQUENCE; PHENOTYPE; POPULATION GENETICS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN MOTIF; REPORTER GENE;

BASE PAIR MISMATCH; BASE SEQUENCE; COLORECTAL NEOPLASMS; DNA PRIMERS; HUMANS; MOLECULAR SEQUENCE DATA; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); PROTEINS; REPETITIVE SEQUENCES, NUCLEIC ACID; SELENIUM; SELENOPROTEIN P; SELENOPROTEINS;

ANIMALIA;

EID: 0036711985     PISSN: 10184813     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.ejhg.5200811     Document Type: Article

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