Contributions of genetic risk and fetal hypoxia to hippocampal volume in patients with schizophrenia or schizoaffective disorder, their unaffected siblings, and healthy unrelated volunteers

American Journal of Psychiatry

Volumn 159, Issue 9, 2002, Pages 1514-1520

  Van Erp, Theo G M ^a   Saleh, Peter A ^a   Rosso, Isabelle M ^a   Huttunen, Matti ^a   Lönnqvist, Jouko ^a   Pirkola, Tiia ^a   Salonen, Oili ^a   Valanne, Leena ^a   Poutanen, Veli Pekka ^a   Standertskjöld Nordenstam, Carl Gustav ^a   Cannon, Tyrone D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; BRAIN SIZE; CONTROLLED STUDY; DISEASE ASSOCIATION; ENVIRONMENTAL FACTOR; FEMALE; FETUS HYPOXIA; GENETIC PREDISPOSITION; GENETIC RISK; GENETIC SUSCEPTIBILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; ONSET AGE; PRIORITY JOURNAL; SCHIZOIDISM; SCHIZOPHRENIA; SIBLING; VOLUNTEER;

ADULT; AGE OF ONSET; FAMILY CHARACTERISTICS; FEMALE; FETAL HYPOXIA; FUNCTIONAL LATERALITY; GENETIC PREDISPOSITION TO DISEASE; HIPPOCAMPUS; HUMANS; MALE; PREGNANCY; PSYCHOTIC DISORDERS; RISK FACTORS; SCHIZOPHRENIA;

EID: 0036711803     PISSN: 0002953X     EISSN: None     Source Type: Journal    
DOI: 10.1176/appi.ajp.159.9.1514     Document Type: Article

References (40)

1. Volumes of brain structures in twins discordant for schizophrenia
2. Magnetic resonance imaging and spectroscopy in offspring at risk for schizophrenia: Preliminary studies
3. Brain morphology in adolescents at genetic risk for schizophrenia assessed by qualitative and quantitative magnetic resonance imaging
4. Magnetic resonance imaging of brain in people at high risk of developing schizophrenia
5. Reduced subcortical brain volumes in nonpsychotic siblings of schizophrenic patients: A pilot magnetic resonance imaging study
6. Thalamic and amygdala-hippocampal volume reductions in first-degree relatives of patients with schizophrenia: An MRI-based morphometric analysis
7. Anatomical abnormalities in the brains of monozygotic twins discordant for schizophrenia
8. Relationship of obstetric complications and differences in size of brain structures in monozygotic twin pairs discordant for schizophrenia
9. On the nature and mechanisms of obstetric influences in schizophrenia: A review and synthesis of epidemiologic studies
10. Hippocampal volume reduction in schizophrenia: Effects of genetic risk and pregnancy and birth complications
11. Obstetric complications, neurodevelopmental deviance, and risk of schizophrenia
12. Maternal recall bias in the obstetric histories of individuals with and at increased risk of schizophrenia
13. Breakdown in individuals at high risk for schizophrenia: Possible predispositional perinatal factors
14. Genetic variation in vulnerability to the behavioral effects of neonatal hippocampal damage in rats
15. Obstetric complications and age at onset in schizophrenia: An international collaborative metaanalysis of individual patient data
16. Obstetric risk factors for early-onset schizophrenia in a Finnish birth cohort
17. A prospective cohort study of genetic and perinatal influences in the etiology of schizophrenia
18. The spectrum of structural brain changes in schizophrenia: Age of onset as a predictor of cognitive and clinical impairments and their cerebral correlates
19. Cognitive deficits distinguish patients with adolescent- and adult-onset schizophrenia
20. Reduction in temporal lobe size in siblings with schizophrenia: A magnetic resonance imaging study
21. Evidence of reduced temporolimbic structure volumes in schizophrenia
22. The genetic epidemiology of schizophrenia in a Finnish twin cohort: A population-based modeling study
23. Regional gray matter, white matter, and cerebrospinal fluid distributions in schizophrenic patients, their siblings, and controls
24. The Roscommon Family Study, I: Methods, diagnosis of probands, and risk of schizophrenia in relatives
25. A coefficient of agreement for nominal scales
26. The quantitative strength of the social strata of Finnish society
27. An adaptive Bayesian approach to three-dimensional MR brain segmentation
28. An image-processing system for qualitative and quantitative volumetric analysis of brain images
29. A neurohistological correlate of schizophrenia
30. An example-based tour in linear mixed models
31. Problems with ratio and proportion measures of imaged cerebral structures
32. Structural brain abnormalities in patients with schizophrenia and their healthy siblings
33. Fetal hypoxia and structural brain abnormalities in schizophrenic patients, their siblings, and controls
34. Volumetry of hippocampus and amygdala with high-resolution MRI and three-dimensional analysis software: Minimizing the discrepancies between laboratories
35. Hippocampal volume in first-episode psychoses and chronic schizophrenia: A high-resolution magnetic resonance imaging study
36. Evidence of a smaller left hippocampus and left temporal horn in both patients with first episode schizophrenia and normal control subjects
37. Hippocampal volume reduction in schizophrenia as assessed by magnetic resonance imaging: A meta-analytic study
38. Meta-analysis of regional brain volumes in schizophrenia