Orthotopic liver transplant patients require less postoperative morphine than do patients undergoing hepatic resection

Journal of Clinical Anesthesia

Volumn 14, Issue 6, 2002, Pages 416-420

  Moretti, Eugene W ^a   Robertson, Kerri M ^a   Tuttle Newhall, J E ^a   Clavien, Pierre Alain ^a   Gan, Tong Joo ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Analgesia, patient controlled, postoperative; Hepatic resection; Liver transplantation, orthotopic; Morphine

Indexed keywords

MORPHINE;

ADULT; ANALGESIA; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; HUMAN; LIVER RESECTION; LIVER TRANSPLANTATION; PATIENT CONTROLLED ANALGESIA; POSTOPERATIVE PAIN; PRIORITY JOURNAL; RATING SCALE; RETROSPECTIVE STUDY;

ADULT; ANALGESIA, PATIENT-CONTROLLED; ANALGESICS, OPIOID; HEPATECTOMY; HUMANS; LIVER TRANSPLANTATION; MIDDLE AGED; MORPHINE; PAIN MEASUREMENT; PAIN, POSTOPERATIVE; RETROSPECTIVE STUDIES;

EID: 0036711373     PISSN: 09528180     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0952-8180(02)00390-2     Document Type: Article

References (17)

1. Hasselstrom J., Eriksson S., Persson A., Rane J., Svensson J.O., Sawe J. The metabolism and bioavailability of morphine in patients with severe liver cirrhosis. Br J Clin Pharmacol. 29:1990;289-297.
2. Bodenham A., Quinn K., Park G.R. Extrahepatic morphine metabolism in man during the anhepatic phase of OLT. Br J Anaesth. 63:1989;380-384.
3. Patwardhan R.V., Johnson R.F., Hoyumpa A. Jr, et al. Normal metabolism of morphine in cirrhosis. Gastroenterology. 81:1981;1006-1011.
4. Crotty B., Watson K.J., Desmond P.V., et al. Hepatic extraction of morphine is impaired in cirrhosis. Eur J Clin Pharmacol. 36:1989;501-506.
5. Shelly M.P., Cory E.P., Park G.R. Pharmacokinetics of morphine in two children before and after liver transportation. Br J Anaesth. 58:1986;1218-1223.
6. Mazoit J.X., Sandouk P., Zetlaoui P., Scherrmann J.M. Pharmacokinetics of unchanged morphine in normal and cirrhotic subjects. Anesth Analg. 66:1987;293-298.
7. Chauvin M., Sandouk P., Scherrmann J.M., Farinotti R., Strumza P., Duvaldestin P. Morphine pharmacokinetics in renal failure. Anesthesiology. 66:1987;327-331.
8. Kelley S.D., Cauldwell C.B., Fisher D.M., Lau M., Sharma M.L., Weisiger R.A. Recovery of hepatic drug extraction after hypothermic preservation. Anesthesiology. 82:1995;251-258.
9. Schafer M., Carter L., Stein C. Interleukin 1 beta and corticotropin-releasing factor inhibit pain by releasing opioids from immune cells in inflamed tissue. Proc Natl Acad Sci USA. 91:1994;4219-4223.
10. Suzuki T., Yoshiike M., Funada M., Mizoguchi H., Kamei J., Misawa M. Effect of cyclosporine A on the morphine induced place preference. Neurosci Lett. 160:1993;159-162.
11. Czlonkowski A., Stein C., Herz A. Peripheral mechanisms of opioid antinociception in inflammation involvement of cytokines . Eur J Pharmacol. 242:1993;229-235.
12. Kjaer M., Jurlander J., Keiding S., Galbo H., Kirkegaard P., Hage E. No reinnervation of hepatic sympathetic nerves after liver transplantation in human subjects. J Hepatol. 20:1994;97-100.
13. Eisenach J.C., Plevak D.J., Van Dyke R.A., et al. Comparison of analgesic requirements after liver transplantation and cholecystectomy. Mayo Clin Proc. 64:1989;356-359.
14. Donovan K.L., Janicki P.K., Franks W.T., Striepe V.I., Pinson C.W. Liver transplantation is associated with increased met-enkephalin levels in the pig. Acta Anaesthesiol Scand. 40:1996;1161-1165.
15. Donovan K.L., Janicki P.K., Striepe V.I., Stoica C., Franks W.T., Pinson C.W. Decreased patient analgesic requirements after liver transplantation and associated neuropeptide levels. Transplantation. 63:1997;1423-1429.
16. Hill H.F., Mather L.E. Patient-controlled analgesic. Pharmacokinetic and therapeutic considerations. Clin Pharmacokinet. 24:1993;124-140.
17. Glass P.S., Estok P., Ginsberg B., Goldberg J.S., Sladen R.N. Use of patient controlled analgesia to compare the efficacy of epidural to intravenous fentanyl administration. Anesth Analg. 74:1992;345-351.