Differential effects of spinal CNQX on two populations of dorsal horn neurons responding to colorectal distension in the rat

Pain

Volumn 99, Issue 1-2, 2002, Pages 217-222

  Ji, Yaping ^a   Traub, Richard J ^a,b  

^a UNIVERSITY OF MARYLAND DENTAL SCHOOL   (United States)

^b UNIVERSITY OF MARYLAND   (United States)

Author keywords

Non NMDA receptors; Spinal cord; Visceral pain

Indexed keywords

6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; IONOTROPIC RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COLON; CONTROLLED STUDY; CORRELATION ANALYSIS; MALE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; RAT; RECTUM; SPINAL CORD; SPINAL CORD DORSAL HORN; TOUCH;

6-CYANO-7-NITROQUINOXALINE-2,3-DIONE; ANIMALS; COLON; DILATATION; EXCITATORY AMINO ACID ANTAGONISTS; MALE; PAIN; POSTERIOR HORN CELLS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, AMPA; RECEPTORS, KAINIC ACID; RECTUM; VISCERAL AFFERENTS;

EID: 0036711076     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(02)00106-9     Document Type: Article

References (31)

1. Al-Chaer E.D., Lawand N.B., Westlund K.N., Willis W.D. Pelvic visceral input into the nucleus gracilis is largely mediated by the postsynaptic dorsal column pathway. J Neurophysiol. 76:1996;2675-2690.
2. Bennett A.D., Everhart A.W., Hulsebosch C.E. Intrathecal administration of an NMDA or a non-NMDA receptor antagonist reduces mechanical but not thermal allodynia in a rodent model of chronic central pain after spinal cord injury. Brain Res. 859:2000;72-82.
3. Coderre T.J., Melzack R. The contribution of excitatory amino acids to central sensitization and persistent nociception after formalin-induced tissue injury. J Neurosci. 12:1992;3665-3670.
4. Coderre T.J., Melzack R. The role of NMDA receptor-operated calcium channels in persistent nociception after formalin-induced tissue injury. J Neurosci. 12:1992;3671-3675.
5. Coutinho S.V., Meller S.T., Gebhart G.F. Intracolonic zymosan produces visceral hyperalgesia in the rat that is mediated by spinal NMDA and nonNMDA receptors. Brain Res. 736:1996;7-15.
6. Cumberbatch M.J., Chizh B.A., Headley P.M. AMPA receptors have an equal role in spinal nociceptive and non-nociceptive transmission. NeuroReport. 5:1994;877-880.
7. Dickenson A.H., Sullivan A.F. Differential effects of excitatory amino acid antagonists on dorsal horn nociceptive neurons in the rat. Brain Res. 506:1990;31-39.
8. Haley J.E., Sullivan A.F., Dickenson A.H. Evidence for spinal N-methyl-D-aspartate receptor involvement in prolonged chemical nociception in the rat. Brain Res. 518:1990;218-226.
9. Ji Y, Traub RJ. CNQX differentially influences responses of two populations of spinal dorsal horn neurons to colorectal distention in the rat. Soc Neurosci Abstr 2001a;27:Program No. 617.9.
10. Ji Y., Traub R.J. Spinal NMDA receptors contribute to neuronal processing of acute noxious and nonnoxious colorectal stimulation in the rat. J Neurophysiol. 86:2001;1783-1791.
11. Kakizaki H., Yoshiyama M., De Groat W.C. Role of NMDA and AMPA glutamatergic transmission in spinal c-fos expression after urinary tract irritation. Am J Physiol. 270:1996;R990-R996.
12. Kozlowski C.M., Bountra C., Grundy D. The effect of fentanyl, DNQX and MK-801 on dorsal horn neurons responsive to colorectal distension in the anaesthetized rat. Neurogastroenterol Motil. 12:2000;239-247.
13. Lutfy K., Cai S.X., Woodward R.M., Weber E. Antinociceptive effects of NMDA and non-NMDA receptor antagonists in the tail flick test in mice. Pain. 70:1997;31-40.
14. Ness T.J. Evidence for ascending visceral nociceptive information in the dorsal midline and lateral spinal cord. Pain. 87:2000;83-88.
15. Ness T.J., Gebhart G.F. Characterization of neuronal responses to noxious visceral and somatic stimuli in the medial lumbosacral spinal cord of the rat. J Neurophysiol. 57:1987;1867-1892.
16. Ness T.J., Gebhart G.F. Characterization of neurons responsive to noxious colorectal distention in the T13-L2 spinal cord of the rat. J Neurophysiol. 60:1988;1419-1438.
17. Ness T.J., Gebhart G.F. Differential effects of morphine and clonidine on visceral and cutaneous spinal nociceptive transmission in the rat. J Neurophysiol. 62:1989;220-230.
18. Ness T.J., Gebhart G.F. Acute inflammation differentially alters the activity of two classes of rat spinal visceral nociceptive neurons. Neurosci Lett. 281:2000;131-134.
19. Ness T.J., Piper J.G., Follett K.A. The effect of spinal analgesia on visceral nociceptive neurons in caudal medulla of the rat. Anesth Analg. 89:1999;721-726.
20. Nishiyama T. Interaction among NMDA receptor-, NMDA glycine site- and AMPA receptor antagonists in spinally mediated analgesia. Can J Anaesth. 47:2000;693-698.
21. Nishiyama T., Gyermek L., Lee C.M., Kawasaki-Yatsugi S., Yamaguchi T. The systemically administered competitive AMPA receptor antagonist, YM872, has analgesic effects on thermal or formalin-induced pain in rats. Anesth Analg. 89:1999;1534-1537.
22. Olivar T., Cervero F., Laird J.M. Responses of rat spinal neurons to natural and electrical stimulation of colonic afferents: effect of inflammation. Brain Res. 866:2000;168-177.
23. Ren K., Dubner R.D. NMDA receptor antagonists attenuate mechanical hyperalgesia in rats with unilateral inflammation of the hindpaw. Neurosci Lett. 163:1993;22-26.
24. Ren K., Hylden J.L.K., Williams G.M., Ruda M.A., Dubner R. The effects of a non-competitive NMDA receptor antagonist MK-801 on behavioral hyperalgesia and dorsal horn neuronal activity in rats with unilateral inflammation. Pain. 50:1992;331-344.
25. Ren K., Williams G.M., Hylden J.L.K., Ruda M.A., Dubner R. The intrathecal administration of excitatory amino acid receptor antagonists selectively attenuated carrageenan-induced behavioral hyperalgesia in rats. Eur J Pharmacol. 219:1992;235-243.
26. Sakurada T., Wako K., Sugiyama A., Sakurada C., Tan-No K., Kisara K. Involvement of spinal NMDA receptors in capsaicin-induced nociception. Pharmacol Biochem Behav. 59:1998;339-345.
27. 2+ permeable AMPA receptor antagonist. NeuroReport. 10:1999;3523-3526.
28. Traub RJ, Zhai QZ, Ji Y, Kovalenko M. NMDA receptor antagonists attenuate noxious and nonnoxious colorectal distention-induced Fos expression and the visceromotor reflex. Neuroscience 2002 (in press).
29. Woolf C.J., Thompson S.W.N. The induction and maintenance of central sensitization is dependent on N-methyl-D-aspartic acid receptor activation; implications for the treatment of post-injury pain hypersensitivity states. Pain. 44:1991;293-299.
30. Yoshiyama M., Roppolo J.R., De Groat W.C. Interactions between NMDA and AMPA/kainite receptors in the control of micturition in the rat. Eur J Pharmacol. 287:1995;73-78.
31. Zhai Q.Z., Traub R.J. The NMDA receptor antagonist MK-801 attenuates c-Fos expression in the lumbosacral spinal cord following repetitive noxious and nonnoxious colorectal distention. Pain. 83:1999;321-329.