Genetics of asthma

Medical Clinics of North America

Volumn 86, Issue 5, 2002, Pages 937-950

  Blumenthal, Jacob Bryan ^a   Blumenthal, Malcolm N ^b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASTHMA; ATOPY; CHROMOSOMAL LOCALIZATION; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE PREDISPOSITION; ENVIRONMENTAL FACTOR; GENE; GENE EXPRESSION; GENE INTERACTION; GENETIC LINKAGE; GENETIC PREDISPOSITION; GENETIC VARIABILITY; HEREDITY; HUMAN; INFLAMMATION; LUNG; PHENOTYPE; PRIORITY JOURNAL; REVIEW; SKIN TEST;

ASTHMA; GENETIC PREDISPOSITION TO DISEASE; HUMANS;

EID: 0036710670     PISSN: 00257125     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0025-7125(02)00028-7     Document Type: Review

References (54)

1. Pirquet CV. Allergy. In: Gell PGH, Coombs RRA, editors. Clinical Aspects of Immunology. Philadelphia: FA Davis Company; 1963. p. 1457.
2. Coca AF, Cooke RA. On the classification of the phenomenon of hypersensitiveness. J Immunol 1923;8:163-82.
3. Blumenthal MN. Principles of genetics. In: Middleton E, Reed C, Ellis E, et al, editors. Allergy: Principles and Practice. St. Louis: Mosby-Year Book; 1998. p. 28-39.
4. Homburger H. Methods in laboratory immunology. In: Middleton E, Reed C, Ellis E, et al, editors. Allergy: Principles and practice. St. Louis: Mosby-Year Book; 1998. p. 417-29.
5. Blumenthal MN. Epidemiology and genetics of asthma and allergy. In: Kaplan A, editor. Allergy. Philadelphia: WB Saunders; 1997. p. 407-20.
6. Graves PE, Kabesch M, Halonen M, et al. A cluster of seven tightly linked polymorphisms in the IL-13 gene is associated with total serum IgE levels in three populations of white children. J Allergy Clin Immunol 2000;105:506-13.
7. Pierson-Mullan LK, Jackola DR, Blumenthal MN, et al. Characterization of polyclonal allergen-specific IgE response by affinity distributions. Mol Immunol 2001;37:613-20.
8. Pierson-Mullany L, Jackola D, Blumenthal MN, et al. Evidence of an infinity threshold for IgE-allergen binding in the percutaneous skin test reaction. Clin Exp Allergy 2001;32:1-10.
9. National Heart Lung and Blood Institute, National Institute of Health. Guidelines for the Diagnosis and Management of Asthma. Washington, DC: US Government Printing Office; 1995.
10. Blumenthal MN. Historical perspectives. In: Blumenthal MN, Björkstén B, editors. Genetics of allergy and asthma. New York: Marcel Dekker; 1997. p. 1-18.
11. Burrows B, Martinez F, Halonen, et al. Association of asthma with serum IgE level and skin test reactivity to allergens. N Engl J Med 1989;320:271.
12. Sears M, Burrows B, Flannery G, et al. Relationship between airway responsiveness and serum IgE in children with asthma and in apparently normal children. N Engl J Med 1991;325:1067.
13. Blumenthal MN, Ober C, Bleecker E, et al. Linkage analysis of a genome scan for skin test reactivity to allergens. Am J Respir Crit Care Med 2001;163:A960.
14. Lester LA, Blumenthal MN, Marsh DG, et al. Ethnic-specific differences in asthma and associated phenotypes in The Collaborative Study on the Genetics of Asthma (CSGA). J Allergy Clin Immunol 2001;108:357-62.
15. Jackola D, Pierson-Mullany L, Corazalla E, et al. Pathophysiological states associated with asthma and atopy. J Allergy Clin Immunol 1999;103:S177.
16. Palmer LJ, Burton PR, Faux JA, et al. Independent inheritance of serum immunoglobulin E concentrations and airway responsiveness. Am J Respir Crit Care Med 2000;161: 1836-43.
17. st century. Clin Rev Allergy Immunol 2002;22:11-32.
18. Hakonarson H, Bjornsdottir U, Ostermann E, et al. Allelic frequencies and patterns of single-nucleotide polymorphism in candidate genes for asthma and atopy in Iceland. Am J Respir Crit Care Med 2001;164:2036-44.
19. Cookson WOC, Moffatt MF. Genetics of asthma and allergic disease. Hum Mol Genet 2000;9:2359-64.
20. Marsh D, Neely DR, Breazeale G, et al. Linkage analysis of IL-4 and other chromosome Sq31.1 markers and total serum immunoglobulin E concentration. Science 1994;264: 1152-6.
21. Rosenwasser LJ, Klemm DJ, Dresback H, et al. Promoter polymorphisms in chromosome 5 gene cluster in asthma and atopy. Clin Exp Allergy 1995;25:74-8.
22. Noguchi E, Shibasaki M, Arinami T, et al. Association of asthma and the interleukin-4 promoter gene in Japanese. Clin Exp Allergy 1998;28:449-53.
23. Dizier M, Sandford A, Walley A, et al. Indication of linkage of serum IgE levels to the interleukin-4 gene and exclusion of the contribution of the (-590 C to T) interleukin-4 promoter polymorphism to IgE variation. Genet Epidemiol 1999;16:84-9.
24. Hijazi Z, Haider MZ. Interleukin-4 gene promoter polymorphism [C590T] and asthma in Kuwaiti Arabs. Int Arch Allergy Immunol 2000;122:190-4.
25. Baldini M, Lohman I, Halonen M, et al. A polymorphism* in the 5' flanking region of the CD14 gene is associated with circulating soluble CD14 levels and with total serum immunoglobulin E. Am J Respir Cell Mol Biol 1999;20:976-83.
26. 2-Adrenergic receptor pharmacogenetics. Am J Respir Crit Care Med 2000;3: S197-201.
27. Cookson WOC, Sharp PA, Faux JA, et al. Linkage between immunoglobulin E responses underlying asthma and rhinitis and chromosome 11q. Lancet 1989;1:1292-5.
28. Hershey GK, Friedrich MF, Esswein LA, et al. The association of atopy with a gain of function mutation in the alpha subunit of the interleukin-4 receptor. N Engl J Med 1997; 337:1720-5.
29. Deichmann KA, Heinzmann A, Forster J, et al. Linkage and allelic association of atopy and markers flanking the IL-4 receptor gene. Clin Exp Allergy 1998;28:151-5.
30. Ober C, Leavitt SA, Tsalenko A, et al. Variation in the interleukin 4-receptor alpha gene confers susceptibility to asthma and atopy in ethnically diverse populations. Am J Hum Genet 2000;66:517-26.
31. Mitsuyasu H, Izuhara K, Mao XQ, et al. Ile50Val variant of IL4R alpha upregulates IgE synthesis and associates with atopic asthma. Nat Genet 1998;19:119-20.
32. Xu JF, Postma DS, Howard TD, et al. Major genes regulating total serum immunoglobulin E levels in families with asthma. Am J Hum Genet 2000;67:1163-73.
33. Daniels SE, Bhattacharrya S, James AJ, et al. A genome-wide search for quantitative loci underlying asthma. Nature 1996;383:250.
34. Dizier M, Besse-Schmittler C, Guilloud-Bataille M, et al. Genome screen for asthma and related phenotypes in the French EGEA study. Am J Respir Crit Care Med 2000;162: 1812-8.
35. Wjst M, Fischer G, Immervoll T, et al. A genome-wide search for linkage to asthma. Genomics 1999;58:1-8.
36. Laitinen T, Daly M, Rioux J, et al. A susceptibility for asthma-related traits on chromosome 7 revealed by genome-wide scan in a founder population. Nat Genet 2001;28:87-91.
37. Xu Xin, Fang Z, Wang B, et al. A Genome-wide search for quantitative-trait loci underlying asthma. Am J Hum Genet 2001;69:1271-7.
38. Mathias RA, Freidhoff LR, Blumenthal MN, et al. A genome-wide linkage analyses of total serum IgE using variance components analysis in asthmatic families. Genet Epidemiol 2001;20:340-55.
39. Ober C, Tsalenko A, Parry R, et al. A second-generation genome wide screen for asthma-susceptibility alleles in a founder population. Am J Hum Genet 2000;67:1154-62.
40. Blumenthal MN, Bleecker ER, Barnes K, et al. Genome screen for atopy and skin test responsiveness (STR) susceptibility loci in U.S. populations. J Allergy Clin Immunol 1999;103:S174.
41. Blumenthal JB, Blumenthal MN. Immunogenetics of allergy and asthma. Allergy Clinics of North America 1996;16:517-34.
42. Howell WM, Holgate ST. HLA genetics and allergic disease. Thorax 1995;50:815-8.
43. Marsh D, Rafnar T, Ghosh G, et al. Specific immune responses to purified allergens. In: Blumenthal MN, Björkstén B, editors. Genetics of allergy and asthma. New York: Marcel Dekker; 1997. p. 197-210.
44. Cooke RA, Vander Veer A. Human sensitization. J Immunol 1916;1:201-305.
45. Varadarajulu S, Helm T, Mellen BG, et al. Relative risk for asthma in first degree relatives. Annual meeting of the American Academy of Allergy, Asthma and Immunology (AAAAI). J Allergy Clin Immunol 2001;107:S280.
46. Liggett S. The pharmacogenetics of β2-adrenergic receptors: Relevance to asthma. J Allergy Clin Immunol 2000;105:S487-92.
47. Hall I. Genetic factors in asthma severity. Clin Exp Allergy 1998;28:S16-20.
48. Lane S, Arm J, Staynov D, Lee T. Chemical mutational analysis of the human glucocorticoid receptor cDNA in glucocorticoid-resistant bronchial asthma. Am J Respir Cell Mol Biol 1994;11:42-8.
49. Heinzmann A, Mao XQ, Akaiwa M, et al. Genetic variants of IL-13 signaling and human asthma and atopy. Hum Mol Genet 2000;9:549-59.
50. Albuquerque RV, Hayden CM, Palmer LJ, et al. Association of polymorphisms within the tumour necrosis factor (TNF) genes and childhood asthma. Clin Exp Allergy 1998;28: 578-84.
51. Moffatt MF, Cookson WOC. Tumor necrosis factor haplotypes and asthma. Hum Mol Genet 1997;6:551-4.
52. Xu JF, Meyers DA, Ober C, et al. Genome wide screen and identifying gene-gene interactions for asthma susceptibility loci in three U.S. populations: Collaborative Study on the Genetics of Asthma (CSGA). Am J Human Genet 2001;68:1437-46.
53. Ober C, Cox N, Abney M. The collaborative study on the genetics of asthma: Genome wide search for asthma susceptibility loci in a founder population. Hum Mol Genet 1998;7: 1393-8.
54. Yokouchi Y, Nukaga Y, Sshibassaki M, et al. Significant evidence for linkage of mite sensitive childhood asthma to chromosome 5131-q33 near the interleukin 12B locus by a genome wide screen in Japanese families. Genomics 2000;66:152-60.