NF-κB and I-κB overexpression in articular chondrocytes with progression of type II collagen-induced arthritis in DBA/1 mouse knees

Clinical and Experimental Rheumatology

Volumn 20, Issue 5, 2002, Pages 647-652

  Eguchi, Jun ^a   Koshino, Tomihisa ^a   Takagi, Toshitaka ^a   Hayashi, Takeshi ^a   Saito, Tomoyuki ^a  

^a YOKOHAMA CITY UNIVERSITY   (Japan)

Author keywords

Cartilage destruction; Collagen induced arthritis; DBA 1 mouse; I B; NF B

Indexed keywords

COLLAGEN TYPE 2; EOSIN; FREUND ADJUVANT; HEMATOXYLIN; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN ANTIBODY; TOLONIUM CHLORIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARTILAGE CELL; CARTILAGE DEGENERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DISEASE COURSE; GENE OVEREXPRESSION; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INTRACELLULAR TRANSPORT; KNEE ARTHRITIS; MALE; MOUSE; NONHUMAN; PERICHONDRIUM; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; TISSUE SECTION;

ANIMALS; ARTHRITIS, EXPERIMENTAL; CARTILAGE, ARTICULAR; CHONDROCYTES; COLLAGEN TYPE II; I-KAPPA B PROTEINS; IMMUNOHISTOCHEMISTRY; KNEE JOINT; MICE; MICE, INBRED DBA; NF-KAPPA B;

EID: 0036709337     PISSN: 0392856X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. BAEUERLE PA, BALTIMORE D: The physiology of NF-κB transcription factor. In COHEN P and FOULKES JG (Eds.): The Hormonal Control of Gene Transcription. Amsterdam, Elseveir, 1991.
2. BLAKE DR, WINYARD PG, MAROK R: The contribution of hypoxic-reperfusion injury to inflammatory synovitis: the influence of reactive oxygen intermediates on the transcriptional control of inflammation. Ann NY Acad Sci 1994; 723: 308-17.
3. BEAUPARLANT P, HISCOTT J: Biological and biochemical inhibitors of the NF-kappa B/Rel proteins and cytokines synthesis. Cyt Growth Factor Rev 1996; 7: 175-90.
4. CHEN CC, MANNING AM: Transcriptional regulation of endothelial cell adhesion molecules: A dominant role for NF-kappa B. Agents Actions Suppl. 1995; 47: 135-41.
5. VERMA IM, STEVENSON JK, SCHWARZ EM, VAN ANTWERP D, MIYAMOTO S: Rel/NF-kappa B/I kappa B family: Intimate tales of association and dissociation. Gene Dev 1995; 15: 2723-35.
6. BAEUERLE PA, BALTOMORE D: I kappa B: A specific inhibitor of the NF-kappa B transcription factor. Science 1988; 242: 540-6.
7. MIYAMOTO S, CHIANO PJ, VERMA IM: Enhanced I kappa B alpha degradation is responsible for constitutive NF-kappa B activity in mature murine B-cell lines. Mol Cell Biol 1994; 14: 3276-82.
8. SATO MI, KOSHINO T, TAKAGI T: CD44 expression on chondrocytes in knees of DBA/1 mice with type II collagen-induced arthritis. Clin Exp Rheumatol 1999; 17: 185-90.
9. TAKAGI T, OKAMOTO R, KOSHINO T et al.: Up-regulation of CD44 in rheumatoid chondrocytes. Scand J Rheumatol 2001; 30: 110-3.
10. TAKAGI T, JASIN HE: Interactions of synovial fluid immunoglobulins with chondrocytes. Arthritis Rheum 1992; 35: 1502-9.
11. HAYASHI T, JASIN HE: Nitric oxide production by superficial and deep articular chondrocytes. Arthritis Rheum 1997; 40: 261-9.
12. TRENTHAM DE, TOWNES AS, KANG AH: Autoimmunity of type II collagen: An experimental model of arthritis. J Exp Med 1977; 146: 857-8.
13. VERDRENGH M, HOLMADAHL R, TARKOWSKI A: Administration of antibodies to hyaluronan receptor (CD44) delays the start and ameliorates the severity of collagen II arthritis. J Exp Med 1977; 146: 857-8.
14. TAKAGI T, KOSHINO T, JASIN HE: Isolation and differential selection of metalloproteinase by superficial chondrocytes in articular cartilage. International Orthop 1998; 22: 55-8.
15. COURTENAY JS, DALLMAN MJ, DAYAN AB, MARTEN A, MOSEDALE B: Immunization against heterologous type II collagen induced arthritis in mice. Nature 1980; 2843: 666-8.
16. TAK PP, FIRESTEIN GS: NF-κB: A key role in inflammatory diseases. J Clin Invest 2001; 107: 7-11.
17. MARINOVA-MUTAFCHIEVA L, WILLIAMS RO, MASON LJ et al.: Dynamics of proinflammatory cytokine expression in the joints of mice with collagen-induced arthritis (CIA). Clin Exp Immuno 1997; 107: 507-12.
18. YAMASAKI S, KAWAKAMI A, NAKASHITA T et al.: Importance of NF-κB in rheumatoid synovial tissue: in situ NF-κB expression and in vitro study using cultured synovial cells. Ann Rheum Dis 2001; 60: 678-84.
19. ZHANG HG, HUANG N, LIU D et al.: Gene therapy that inhibits human translocation of nuclear factor κB results in tumor necrosis factor α-induced apoptosis of human synovial fibroblasts. Arthritis Rheum 2000; 43: 1094-105.
20. TOMITA T, TAKEUCHI E, TOMITA N et al.: Suppressed severity of collagen-induced arthritis by in vivo transfection of nuclear factor κB decoy oligodeoxynucleotides as a gene therapy. Arthritis Rheum 1999; 42: 2532-42.
21. SYLVESTER J, LIACINI A, LI WQ, DEHNADE F, ZAFARULLAH M: Tripterygium wilfordii Hook F extract suppresses proinflammatory cytokine-induced expression of matrix metalloproteinase genes in articular chondrocytes by inhibiting activating protein-1 and nuclear factor-kappaB activities. Mol Pharmacol 2001; 59: 1196-205.
22. TAK PP, GERLAG MD, AUPPERLE KR et al: Inhibitor of nuclear factor of κB kinase β is a key regulator of synovial inflammation. Arthritis Rheum 2001; 44: 1897-907.