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Volumn 4, Issue 5, 2002, Pages 449-463
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Antibody-directed effector cell therapy of tumors: Analysis and optimization using a physiologically based pharmacokinetic model
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Author keywords
Bifunctional antibody; Lymphocyte; Mathematical model; Trafficking; Tumor localization
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Indexed keywords
BIFUNCTIONAL ANTIBODY;
CANCER ANTIBODY;
CD3 ANTIGEN;
EPITOPE;
TUMOR ANTIGEN;
UNCLASSIFIED DRUG;
BISPECIFIC ANTIBODY;
TUMOR PROTEIN;
ADOPTIVE TRANSFER;
ANTIBODY DEPENDENT LYMPHOCYTOTOXICITY;
ANTIGEN BINDING;
ARTICLE;
BINDING AFFINITY;
CANCER IMMUNOTHERAPY;
CROSS LINKING;
DRUG DESIGN;
DRUG TARGETING;
EFFECTOR CELL;
LEUKOCYTE ADHERENCE;
MATHEMATICAL MODEL;
MOLECULAR INTERACTION;
PRIORITY JOURNAL;
TUMOR CELL;
TUMOR ESCAPE;
ANIMAL;
ANTIBODY SPECIFICITY;
BIOLOGICAL MODEL;
CYTOTOXICITY;
DRUG EFFECT;
HUMAN;
IMMUNOLOGY;
IMMUNOTHERAPY;
LYMPHOCYTE;
LYMPHOCYTE ACTIVATION;
METABOLISM;
NEOPLASM;
SPECIES DIFFERENCE;
ANIMALS;
ANTIBODIES, BISPECIFIC;
ANTIBODIES, NEOPLASM;
ANTIGENS, CD3;
CYTOTOXICITY, IMMUNOLOGIC;
HUMANS;
IMMUNOTHERAPY;
LYMPHOCYTE ACTIVATION;
LYMPHOCYTES;
MODELS, BIOLOGICAL;
NEOPLASM PROTEINS;
NEOPLASMS;
ORGAN SPECIFICITY;
SPECIES SPECIFICITY;
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EID: 0036708512
PISSN: 15228002
EISSN: None
Source Type: Journal
DOI: 10.1038/sj.neo.7900260 Document Type: Article |
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Times cited : (46)
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References (29)
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