Treatment of the infertile patient with polycystic ovarian syndrome

Obstetrical and Gynecological Survey

Volumn 57, Issue 9, 2002, Pages 587-597

  Pritts, Elizabeth Anna ^a  

^a University of Wisconsin Health   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIANDROGEN; CLOMIFENE CITRATE; CORTISONE; CYPROTERONE ACETATE; FOLLITROPIN; GLUCOCORTICOID; GONADORELIN; GONADORELIN AGONIST; GONADOTROPIN; INHIBIN; INOSITOL; INSULIN; KETOCONAZOLE; LUTEINIZING HORMONE; METFORMIN; NALTREXONE; OPIATE ANTAGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PLACEBO; PRASTERONE; RECOMBINANT FOLLITROPIN; SEX HORMONE BINDING GLOBULIN; SOMATOMEDIN BINDING PROTEIN 1; SPIRONOLACTONE; TROGLITAZONE; VASCULOTROPIN;

ANOVULATION; CLINICAL TRIAL; DISEASE PREDISPOSITION; FEMALE INFERTILITY; HUMAN; HYPERINSULINEMIA; HYPOTHALAMUS HYPOPHYSIS GONAD SYSTEM; INSULIN SENSITIVITY; OBESITY; OVARY POLYCYSTIC DISEASE; PATHOPHYSIOLOGY; REVIEW; SUBFERTILITY; FEMALE;

ANOVULATION; CLINICAL TRIALS; FEMALE; HUMAN; INFERTILITY, FEMALE; POLYCYSTIC OVARY SYNDROME; HUMANS;

EID: 0036708376     PISSN: 00297828     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006254-200209000-00022     Document Type: Review

References (76)

1. Polycystic ovary syndrome
2. Diagnostic criteria for polycystic ovary syndrome (PCOS): Towards a rational approach
3. Heterogeneity of the polycystic ovary syndrome: Clinical endocrine and ultrasound features in 556 patients
4. Gonadotropic control of ovarian follicular growth and development
5. Follicle-stimulating hormone and advanced follicle development in the human
6. Reproductive physiology
7. Polycystic ovarian syndrome
8. Determinants of abnormal gonadotropin secretion in clinically defined women with polycystic ovary syndrome
9. Inappropriate gonadotropin secretion in polycystic ovary syndrome: Influence of adiposity
10. Role of progesterone deficiency in the development of luteinizing hormone and androgen abnormalities in polycystic ovary syndrome
11. Reduction of gonadotropin-releasing hormone pulse frequency is associated with subsequent selective follicle-stimulating hormone secretion in women with polycystic ovarian disease
12. Mechanisms of hypothalamic-pituitary-gonadal disruption in polycystic ovarian syndrome
13. Do androgens directly regulate gonadotropin secretion in polycystic ovary syndrome?
14. Insulin stimulates testosterone biosynthesis by human thecal cells from women with polycystic ovary syndrome by activating its own receptor and using inositolglycan mediators as the signal transduction system
15. Regulation of androgen production in cultured human thecal cells by insulin-like growth factor I and insulin
16. Insulin resistance and the polycystic ovary syndrome: Mechanism and implications for pathogenesis
17. A direct effect of hyperinsulinemia on serum sex hormone-binding globulin levels in obese women with the polycystic ovary syndrome
18. Insulin regulation of insulin-like growth factor binding protein-1 in obese and nonobese humans
19. The insulin-like growth factor system in normal and abnormal human ovarian follicle development
20. Polycystic ovary syndrome: Clinical aspects
21. Follicular steroids in relation to oocyte development and human ovarian stimulation protocols
22. Hyperandrogenism and hyperinsulinemia
23. Insulin resistance improves in hyperandrogenic women treated with Lupron
24. Suppression of hyperandrogenism does not improve peripheral or hepatic insulin resistance in the polycystic ovary syndrome
25. Effects of metformin on ovulation rate, hormonal and metabolic profiles in women with clomiphene-resistant polycystic ovaries: A randomized, double-blinded placebo-controlled trial
26. The prevalence of polycystic ovaries on ultrasound scanning in a population of randomly selected women
27. Serum testosterone levels in the polycystic ovary syndrome
28. Induction of ovulation with MRL-41
29. An extended regimen of clomiphene citrate in women unresponsive to standard therapy
30. Clomiphene citrate for ovulation induction in women with oligo-amenorrhea
31. The use of cortisone in follicular phase disturbances
32. Effect of dexamethasone and clomiphene citrate on peripheral steroid levels and ovarian function in a hirsute amenorrheic patient
33. Clomiphene and dexamethasone in women unresponsive to clomiphene alone
34. A randomized study of dexamethasone in ovulation induction with clomiphene citrate
35. Gonadotrophin therapy for ovulation induction in subfertility associated with polycystic ovary syndrome
36. Role of vascular endothelial growth factor in ovarian physiology and pathology
37. Angiogenesis and vascular regression in the ovary
38. Role of vascular endothelial growth factor in ovarian hyperstimulation syndrome
39. What's new in the pathogenesis and prevention of ovarian hyperstimulation syndrome?
40. Recombinant FSH versus urinary gonadotrophins or recombinant FSH for ovulation induction in subfertility associated with polycystic ovary syndrome
41. The additional use of buserelin in hMG-ovulation induction in PCO: A double-blind controlled study
42. LH/RH analogues for ovulation induction, with particular reference to polycystic ovary syndrome
43. Combined luteinizing hormone releasing hormone analogue and exogenous gonadotrophins for the treatment of infertility associated with polycystic ovaries
44. The luteal phase in polycystic ovary syndrome during ovulation induction with human menopausal gonadotrophin with and without leuprolide acetate
45. Pulsatile luteinising hormone releasing hormone for ovulation induction in subfertility associated with polycystic ovary syndrome
46. Treatment of anovulation with pulsatile gonadotropin-releasing hormone: Prognostic factors and clinical results in 600 cycles
47. Increased insulin secretion in patients with multifollicular and polycystic ovaries and its impact on ovulation induction
48. Endocrine response determines the clinical outcome of pulsatile gonadotropin-releasing hormone ovulation induction in different ovulatory disorders
49. The abnormal response of polycystic ovarian disease patients to exogenous pulsatile gonadotropin-releasing hormone: Characterization and management
50. Treatment of anovulation by HMG or GnRH: Contribution of a cross-over randomized study to a rational management of PCOS
51. Pulsatile gonadotrophin-releasing hormone stimulation after mediumterm pituitary suppression in polycystic ovary syndrome
52. Strategies for the use of insulin-sensitizing drugs to treat infertility in women with polycystic ovary syndrome
53. Metformin effects on clinical features, endocrine and metabolic profiles and insulin sensitivity in polycystic ovary syndrome: A randomized, double-blind, placebo-controlled 6-month trial, followed by open, long-term clinical evaluation
54. Co-administration of metformin during rFSH treatment in patients with clomiphene citrate-resistant polycystic ovarian syndrome: A prospective randomized trial
55. Effects of diet and metformin administration on sex hormone-binding globulin, androgens, and insulin in hirsute and obese women
56. Can metformin reduce insulin resistance in polycystic ovary syndrome?
57. Effects of metformin on insulin secretion, insulin action, and ovarian steroidogenesis in women with polycystic ovary syndrome
58. Acute and chronic effects of troglitazone (CS-045) on isolated rat ventricular cardiomyocytes
59. Antidiabetic thiazolidinediones block the inhibitory effect of tumor necrosis factor-alpha on differentiation, insulin-stimulated glucose uptake, and gene expression in 3T3-L1 cells
60. Are all glitazones the same?
61. Improvement in insulin sensitivity followed by ovulation and pregnancy in a woman with polycystic ovary syndrome who was treated with rosiglitazone
62. Ovulatory and metabolic effects of D-chiro-inositol in the polycystic ovary syndrome
63. Effects of metformin on spontaneous and clomiphene-induced ovulation in the polycystic ovary syndrome
64. Metformin increases the ovulatory rate and pregnancy rate from clomiphene citrate in patients with polycystic ovary syndrome who are resistant to clomiphene citrate alone
65. Metformin therapy improves ovulatory rates, cervical scores and pregnancy rates in clomiphene citrate-resistant women with polycystic ovary syndrome
66. Surgical treatment of bilateral polycystic ovaries
67. Evaluation of adhesion formation after laparoscopic treatment of polycystic ovarian disease
68. Polycystic ovarian syndrome treated by ovarian electrocautery through the laparoscope
69. Laparoscopic drilling by diathermy or laser for ovulation induction in anovulatory polycystic ovary syndrome
70. Concurrent antagon and follistim therapy for ovulation induction in women with polycystic ovary syndrome (PCOS)
71. Successful induction of ovulation in normogonadotropic clomiphene resistant anovulatory women by combined naltrexone and clomiphene citrate treatment
72. Ovulation induction with adjuvant antiandrogen treatment in Stein-Leventhal syndrome
73. Advances in the diagnosis and treatment of the hirsute patient
74. Ketoconazole therapy: Hormonal and clinical effects in nontumoral hyperandrogenism
75. Improved responsiveness of PCOS patients to clomiphene after CYP17a inhibitor
76. Polycystic ovary syndrome: The new millenium