Reactive nitrogen intermediates have a bacteriostatic effect on Mycobacterium tuberculosis in vitro

Journal of Clinical Microbiology

Volumn 40, Issue 9, 2002, Pages 3162-3166

  Firmani, Marcia A ^a   Riley, Lee W ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROGEN PEROXIDE; NITROGEN DERIVATIVE; SODIUM NITRITE; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE;

ARTICLE; BACTERIAL SURVIVAL; BACTERIOSTASIS; CELL PROLIFERATION; IN VITRO STUDY; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; STRAIN DIFFERENCE; DRUG EFFECT; GROWTH, DEVELOPMENT AND AGING; HUMAN; LUNG TUBERCULOSIS; METHODOLOGY; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY;

HUMAN; HYDROGEN PEROXIDE; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM TUBERCULOSIS; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN SPECIES; SODIUM NITRITE; SUPPORT, U.S. GOV'T, P.H.S.; TUBERCULOSIS, PULMONARY; HUMANS;

EID: 0036708301     PISSN: 00951137     EISSN: None     Source Type: Journal    
DOI: 10.1128/JCM.40.9.3162-3166.2002     Document Type: Article

References (26)

1. Effects of nitric oxide inhibitors on murine infection with Mycobacterium tuberculosis
2. Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediates produced by activated murine macrophages
3. Disseminated tuberculosis in interferon-γ gene-disrupted mice
4. Multiple defects of immune cell function in mice with disrupted interferon-γ genes
5. Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages
6. Mycobacterium tuberculosis CDC1551 is resistant to reactive nitrogen and oxygen intermediates in vitro
7. Mycobacterial growth inhibition by interferon-γ-activated bone marrow macrophages and differential susceptibility among strains of Mycobacterium tuberculosis
8. Mechanisms involved in mycobacterial growth inhibition by gamma interferon-activated bone marrow macrophages: Role of reactive nitrogen intermediates
9. An essential role for IFN-γ in resistance to Mycobacterium tuberculosis infection
10. Tumor necrosis factor is required in the protective immune response against Mycobacterium tuberculosis in mice
11. Effects of aminoguanidine on latent murine tuberculosis
12. Widespread dissemination of a drug-susceptible strain of Mycobacterium tuberculosis
13. Lethal Mycobacterium bovis bacillus Calmette-Guérin infection in nitric oxide synthase 2-deficient mice: Cell-mediated immunity requires nitric oxide synthase 2
14. 2 by human mononuclear cells in vitro
15. Host-parasite relationship in experimental airborne tuberculosis. II. Reproducible infection by means of an innoculum preserved at -70°C
16. Virulence and resistance to superoxide, low pH, and hydrogen peroxide among strains of Mycobacterium tuberculosis
17. Induction of nitric oxide in human monocytes and monocyte cell lines by Mycobacterium tuberculosis
18. 2 killing in human monocytes in vitro
19. Identification of nitric oxide synthase as a protective locus against tuberculosis
20. Mycobacterium tuberculosis catalase and peroxidase activities and resistance to oxidative killing in human monocytes in vitro
21. Virulence in the guinea pig, susceptibility to hydrogen peroxide, and catalase activity of isoniazid-senstivie tubercle bacilli from South Indian and British patients
22. Aerosol infection of mice with recombinant BCG-secreting murine IFN-γ partially reconstitutes local protective immunity
23. Strains of Mycobacterium tuberculosis differ in susceptibility to reactive nitrogen intermediates in vitro
24. Susceptibility of a panel of virulent strains of Mycobacterium tuberculosis to reactive nitrogen intermediates
25. An outbreak involving extensive transmission of a virulent strain of Mycobacterium tuberculosis
26. Toxicity of nitrogen oxides and related oxidants on mycobacteria: M. tuberculosis is resistant to peroxynitrite anion