ART-123 Asahi Kasei

Current Opinion in Investigational Drugs

Volumn 3, Issue 8, 2002, Pages 1196-1198

  Khorchidi, Sascha ^a   Bantleon, Ruediger ^a   Kehlbach, Rainer ^a   Tepe, Gunnar ^a   Wiskirchen, Jakub ^a   Duda, Stephan H ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT AGENT; ARGATROBAN; AT 908; DALTEPARIN; HEPARIN; HIRUDIN; PROTEIN C; RECOMBINANT THROMBOMODULIN; THROMBIN;

AREA UNDER THE CURVE; BLEEDING; BLOOD CLOTTING DISORDER; CLINICAL TRIAL; CONTINUOUS INFUSION; DISEASE MODEL; DISSEMINATED INTRAVASCULAR CLOTTING; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG EFFICACY; DRUG ELIMINATION; DRUG HALF LIFE; DRUG METABOLISM; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; IC 50; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PARTIAL THROMBOPLASTIN TIME; PROTHROMBIN TIME; REVIEW; STRUCTURE ACTIVITY RELATION; THROMBIN TIME; THROMBOEMBOLISM;

ANIMALS; BLOOD COAGULATION DISORDERS; CLINICAL TRIALS, PHASE I; CLINICAL TRIALS, PHASE II; CLINICAL TRIALS, PHASE III; HUMANS; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; THROMBOEMBOLISM; THROMBOMODULIN;

EID: 0036707340     PISSN: 14724472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (12)

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7. 442208 Pharmacokinetics and safety of a novel recombinant soluble human thrombomodulin, ART-123, in healthy male volunteers. Nakashima M, Kanamaru M, Umemura K, Tsuruta K J Clin Pharmacol 1998 38 1 40-44
8. 442210 The antithrombotic effects of recombinant human soluble thrombomodulin (rhsTM) on tissue factor-induced disseminated intravascular coagulation in crab-eating monkeys (Macaca fascicularis). Mohri M, Gonda Y, Oka M, Aoki Y, Gomi K, Kiyota T, Sugihara T, Yamamotoi S, Ishida T, Maruyama I Blood Coagul Fibrinolysis 1997 8 5 274-283
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