메뉴 건너뛰기




Volumn 3, Issue 8, 2002, Pages 1230-1233

Selegiline transdermal system: Somerset

Author keywords

[No Author keywords available]

Indexed keywords

AMPHETAMINE; ANTIDEPRESSANT AGENT; CYTOCHROME P450 INHIBITOR; DOPAMINE RECEPTOR STIMULATING AGENT; DRUG METABOLITE; ITRACONAZOLE; METHAMPHETAMINE; MOCLOBEMIDE; MONOAMINE OXIDASE B INHIBITOR; PLACEBO; SELEGILINE;

EID: 0036707267     PISSN: 14724472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (6)

References (36)
  • 2
    • 0013361680 scopus 로고    scopus 로고
    • Watson still on acquisition trail
    • 250573
    • 250573 Watson still on acquisition trail. SCRIP 1997 2234 9
    • (1997) SCRIP , vol.2234 , pp. 9
  • 3
    • 0013450842 scopus 로고    scopus 로고
    • Watson to copromote somerset Eldepryl, Warner-Lambert Zarontin
    • 275389; T&G-6-T&G-7
    • 275389 Watson to copromote somerset Eldepryl, Warner-Lambert Zarontin. FDC Reports Pink Sheet 1997 59 41 T&G-6-T&G-7
    • (1997) FDC Reports Pink Sheet , vol.59 , pp. 41
  • 4
    • 0013360156 scopus 로고    scopus 로고
    • Somerset Pharmaceuticals reports results of clinical trial in major depression
    • 287469; May 19
    • 287469 Somerset Pharmaceuticals reports results of clinical trial in major depression. Somerset Pharmaceuticals Press Release 1998 May 19
    • (1998) Somerset Pharmaceuticals Press Release
  • 6
    • 0013362424 scopus 로고    scopus 로고
    • Somerset announces submission of New Drug Application for EMSAM (Selegiline Transdermal System)
    • 410848; May 25
    • 410848 Somerset announces submission of New Drug Application for EMSAM (Selegiline Transdermal System). Somerset Pharmaceuticals Press Release 2001 May 25
    • (2001) Somerset Pharmaceuticals Press Release
  • 7
    • 76549174465 scopus 로고
    • Phenylisopropylmethyl propinylamine (E-250), a new spectrum psychic energizer
    • 448986
    • 448986 Phenylisopropylmethyl propinylamine (E-250), a new spectrum psychic energizer. Knoll J, Ecseri Z, Kelemen K, Nievel J, Knoll B Arch Int Pharmacodyn Ther 1965 155 1 154-164
    • (1965) Arch Int Pharmacodyn Ther , vol.155 , Issue.1 , pp. 154-164
    • Knoll, J.1    Ecseri, Z.2    Kelemen, K.3    Nievel, J.4    Knoll, B.5
  • 8
    • 0029832107 scopus 로고    scopus 로고
    • Pharmacokinetics and safety of selegiline transdermal system relative to single dose oral administration in the elderly
    • 448987; note
    • 448987 Pharmacokinetics and safety of selegiline transdermal system relative to single dose oral administration in the elderly. Barrett JS, Hochadel TJ, Morales RJ, Rohatagi S, DeWitt KE, Watson SK, DiSanto AR Am J Ther 1996 3 10 688-698 Describes an open-label, two-phase, cross-over study in the elderly, in which STS and metabolites of selegiline
    • (1996) Am J Ther , vol.3 , Issue.10 , pp. 688-698
    • Barrett, J.S.1    Hochadel, T.J.2    Morales, R.J.3    Rohatagi, S.4    DeWitt, K.E.5    Watson, S.K.6    DiSanto, A.R.7
  • 9
    • 0017329403 scopus 로고
    • Substrate- and inhibitor-related characteristiscs of human platelet monoamine oxidase
    • 448988
    • 448988 Substrate- and inhibitor-related characteristiscs of human platelet monoamine oxidase. Donnelly CH, Murphy DL Biochem Pharmacol 1977 26 9 853-858
    • (1977) Biochem Pharmacol , vol.26 , Issue.9 , pp. 853-858
    • Donnelly, C.H.1    Murphy, D.L.2
  • 10
    • 0017594522 scopus 로고
    • Dopamine is a monoamine oxidase B substrate in man
    • 448989
    • 448989 Dopamine is a monoamine oxidase B substrate in man. Glover V, Sandler M, Owen F, Riley GJ Nature 1977 265 5589 80-81
    • (1977) Nature , vol.265 , Issue.5589 , pp. 80-81
    • Glover, V.1    Sandler, M.2    Owen, F.3    Riley, G.J.4
  • 12
    • 0028577499 scopus 로고
    • Pharmacokinetic aspects of I-deprenyl (selegiline) and its metabolism
    • 448991
    • 448991 Pharmacokinetic aspects of I-deprenyl (selegiline) and its metabolism. Heinonen E, Antilla M, Lammintausta R Clin Pharmacol Ther 1994 56 6 742-749
    • (1994) Clin Pharmacol Ther , vol.56 , Issue.6 , pp. 742-749
    • Heinonen, E.1    Antilla, M.2    Lammintausta, R.3
  • 13
    • 0023137631 scopus 로고
    • Dose-dependent effects of deprenyl on CSF monoamine metabolites in patients with Alzheimer's disease
    • 448992
    • 448992 Dose-dependent effects of deprenyl on CSF monoamine metabolites in patients with Alzheimer's disease. Sunderland T, Tariot PN, Cohen RM, Newhouse PA, Mellow AM, Mueller EA Psychopharmacology 1987 91 3 293-296
    • (1987) Psychopharmacology , vol.91 , Issue.3 , pp. 293-296
    • Sunderland, T.1    Tariot, P.N.2    Cohen, R.M.3    Newhouse, P.A.4    Mellow, A.M.5    Mueller, E.A.6
  • 14
    • 0026474638 scopus 로고
    • Gas chromatographic-mass spectrometric determination of plasma selegiline using a deuterated internal standard
    • 448993
    • 448993 Gas chromatographic-mass spectrometric determination of plasma selegiline using a deuterated internal standard. Patrick K, Nguyen B, McCallister J J Chromatogr 1992 583 2 254-258
    • (1992) J Chromatogr , vol.583 , Issue.2 , pp. 254-258
    • Patrick, K.1    Nguyen, B.2    McCallister, J.3
  • 15
    • 0028018502 scopus 로고
    • An enzymatic assay for the MAO-B inhibitor selegiline in plasma
    • 448994
    • 448994 An enzymatic assay for the MAO-B inhibitor selegiline in plasma. Mahmood I, Neau SH, Mason WD J Pharm Biomed Anal 1994 12 7 895-899
    • (1994) J Pharm Biomed Anal , vol.12 , Issue.7 , pp. 895-899
    • Mahmood, I.1    Neau, S.H.2    Mason, W.D.3
  • 16
    • 0030008656 scopus 로고    scopus 로고
    • The effect of dosing regimen and food on the bioavailability of the extensively metabolized, highly variable drug eldepryl ((R)) (selegiline hydrochloride)
    • 448995
    • 448995 The effect of dosing regimen and food on the bioavailability of the extensively metabolized, highly variable drug eldepryl ((R)) (selegiline hydrochloride). Barrett JS, Rohatagi S, Dewwitt KE, Morales RJ, DiSanto AR Am J Ther 1996 3 4 298-313
    • (1996) Am J Ther , vol.3 , Issue.4 , pp. 298-313
    • Barrett, J.S.1    Rohatagi, S.2    Dewwitt, K.E.3    Morales, R.J.4    DiSanto, A.R.5
  • 17
    • 0022638352 scopus 로고
    • Metabolism of deprenyl, a selective monoamine oxidase (MAO) B inhibitor in rat: Relationship of metabolism to MAO-B inhibitory potency
    • 448997
    • 448997 Metabolism of deprenyl, a selective monoamine oxidase (MAO) B inhibitor in rat: Relationship of metabolism to MAO-B inhibitory potency. Yoshida T, Yamada Y, Yamamoto T, Kuroiwa Y Xenobiotica 1986 16 2 129-136
    • (1986) Xenobiotica , vol.16 , Issue.2 , pp. 129-136
    • Yoshida, T.1    Yamada, Y.2    Yamamoto, T.3    Kuroiwa, Y.4
  • 18
    • 0031042161 scopus 로고    scopus 로고
    • Selegiline percutaneous absorption in various species and metabolism by human skin
    • 448998; note
    • 448998 Selegiline percutaneous absorption in various species and metabolism by human skin. Rohtagi S, Barret JS, McDonald LJ, Morris EM, Darnow J, DiSanto AR Pharm Res 1997 14 1 50-55 Metabolism of selegiline by human skin was negligible. The dog was demonstrated to be the most appropriate species for testing the STS.
    • (1997) Pharm Res , vol.14 , Issue.1 , pp. 50-55
    • Rohatagi, S.1    Barret, J.S.2    McDonald, L.J.3    Morris, E.M.4    Darnow, J.5    DiSanto, A.R.6
  • 19
    • 0028316987 scopus 로고
    • Atypical metabolism of deprenyl and its enantiomer, (S)-(+)-N,α-dimethyl-N-propynlphenethylamine, by cytochrome P4502D6
    • 448999
    • 448999 Atypical metabolism of deprenyl and its enantiomer, (S)-(+)-N,α-dimethyl-N-propynlphenethylamine, by cytochrome P4502D6. Grace GM, Kinter MT, Macdonald TL Chem Res Toxicol 1994 7 3 286-290
    • (1994) Chem Res Toxicol , vol.7 , Issue.3 , pp. 286-290
    • Grace, G.M.1    Kinter, M.T.2    Macdonald, T.L.3
  • 21
    • 0035027408 scopus 로고    scopus 로고
    • CYP2C19 polymorphism is not important for the in vivo metabolism of selegiline
    • 449002
    • 449002 CYP2C19 polymorphism is not important for the in vivo metabolism of selegiline. Laine K, Anttila M, Nyman L, Wahlberg A, Bertilsson L Eur J Clin Pharmacol 2001 57 1 137-142
    • (2001) Eur J Clin Pharmacol , vol.57 , Issue.1 , pp. 137-142
    • Laine, K.1    Anttila, M.2    Nyman, L.3    Wahlberg, A.4    Bertilsson, L.5
  • 23
    • 0031785758 scopus 로고    scopus 로고
    • Is 10 milligrams selegiline essential as an adjunct therapy for the symptomatic treatment of Parkinson's disease?
    • 449034
    • 449034 Is 10 milligrams selegiline essential as an adjunct therapy for the symptomatic treatment of Parkinson's disease? Mahmood I Ther Drug Monit 1998 20 6 717-721
    • (1998) Ther Drug Monit , vol.20 , Issue.6 , pp. 717-721
    • Mahmood, I.1
  • 25
    • 0021326523 scopus 로고
    • L-deprenyl plus L-phenylalanine in the treatment of depression
    • 449036
    • 449036 L-deprenyl plus L-phenylalanine in the treatment of depression. Birkmayer W, Riederer P, Linauer W, Knoll J J Neural Transm 1984 59 1 81-87
    • (1984) J Neural Transm , vol.59 , Issue.1 , pp. 81-87
    • Birkmayer, W.1    Riederer, P.2    Linauer, W.3    Knoll, J.4
  • 26
    • 0020462599 scopus 로고
    • Differential efficacy of L-deprenyl, a selective MAO type-B inhibitor, in endogenous and nonendegenous depression
    • 449037
    • 449037 Differential efficacy of L-deprenyl, a selective MAO type-B inhibitor, in endogenous and nonendegenous depression. Mann JJ, Frances A, Peselow ED, Gershon S Psychopharmacol Bull 1982 18 4 182-184
    • (1982) Psychopharmacol Bull , vol.18 , Issue.4 , pp. 182-184
    • Mann, J.J.1    Frances, A.2    Peselow, E.D.3    Gershon, S.4
  • 29
    • 0030818572 scopus 로고    scopus 로고
    • Moclobemide and selegiline in the treatment of depression in Parkinson's disease
    • 449043
    • 449043 Moclobemide and selegiline in the treatment of depression in Parkinson's disease. Steur E, Ballering L J Neurol Neurosurg Psychiatry 1997 63 4 547
    • (1997) J Neurol Neurosurg Psychiatry , vol.63 , Issue.4 , pp. 547
    • Steur, E.1    Ballering, L.2
  • 30
    • 0033958299 scopus 로고    scopus 로고
    • Transdermal selegiline in HIV-associated cognitive impairment: Pilot, placebo-controlled study
    • 449044
    • 449044 Transdermal selegiline in HIV-associated cognitive impairment: Pilot, placebo-controlled study. Sacktor N, Schifitto G, McDermott MP, Marder K, McArthur JC, Kieburtz K Neurology 2000 54 1 233-235
    • (2000) Neurology , vol.54 , Issue.1 , pp. 233-235
    • Sacktor, N.1    Schifitto, G.2    McDermott, M.P.3    Marder, K.4    McArthur, J.C.5    Kieburtz, K.6
  • 31
    • 0003601534 scopus 로고    scopus 로고
    • 449158; Susan Budavari (Ed). Merck Research Laboratories, Whitehouse Station, NJ, USA
    • 449158 The Merck Index (12th Edition). Susan Budavari (Ed). Merck Research Laboratories, Whitehouse Station, NJ, USA 1996.
    • (1996) The Merck Index (12th Edition)
  • 33
    • 0021790704 scopus 로고
    • An improved flurometric assay for brain monoamine oxidase
    • 449221
    • 449221 An improved flurometric assay for brain monoamine oxidase. Morinan A, Garrat HM J Pharmacol Methods 1988 13 3 213-223
    • (1988) J Pharmacol Methods , vol.13 , Issue.3 , pp. 213-223
    • Morinan, A.1    Garrat, H.M.2
  • 34
    • 4243938817 scopus 로고
    • Quantitative determination of selegiline, desmethylselegiline, amphetamine and methamphetamine in human plasma by ion spray LC/MS/MS
    • 449225
    • 449225 Quantitative determination of selegiline, desmethylselegiline, amphetamine and methamphetamine in human plasma by ion spray LC/MS/MS. Mulvana DE, Perkins JR, Henion JD Pharm Res 1993 10 (Suppl) S-331
    • (1993) Pharm Res , vol.10 , Issue.SUPPL.
    • Mulvana, D.E.1    Perkins, J.R.2    Henion, J.D.3
  • 35
    • 0013360343 scopus 로고    scopus 로고
    • Multiple dose pharmacokinetics and dose proportionality of selegiline and metabolites in healthy males following transdermal administration
    • 449227
    • 449227 Multiple dose pharmacokinetics and dose proportionality of selegiline and metabolites in healthy males following transdermal administration. Rohatagi S, Barret JS, Morales R, DeWitt KE Pharm Res 1996 13 (Suppl) S-502
    • (1996) Pharm Res , vol.13 , Issue.SUPPL.
    • Rohatagi, S.1    Barret, J.S.2    Morales, R.3    DeWitt, K.E.4
  • 36
    • 0013408396 scopus 로고    scopus 로고
    • Somerset Pharmaceutical receives 'Not-approvable' letter from FDA for EMSAM
    • 456735; March 27
    • 456735 Somerset Pharmaceutical receives 'Not-approvable' letter from FDA for EMSAM. Somerset Pharmaceuticals Press Release 2002 March 27
    • (2002) Somerset Pharmaceuticals Press Release


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.