메뉴 건너뛰기




Volumn 111, Issue 2, 2002, Pages 219-224

Functional characterization of a natural variant of luteinizing hormone

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; LUTEINIZING HORMONE; PROGESTERONE; PROTEIN;

EID: 0036705559     PISSN: 03406717     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00439-002-0781-8     Document Type: Article
Times cited : (11)

References (38)
  • 1
    • 0019364734 scopus 로고
    • Characterization of several clonal lines of cultured Leydig tumor cells: Gonadotropin receptors and steroidogenic responses
    • Ascoli M (1981) Characterization of several clonal lines of cultured Leydig tumor cells: Gonadotropin receptors and steroidogenic responses. Endocrinology 108:88-95
    • (1981) Endocrinology , vol.108 , pp. 88-95
    • Ascoli, M.1
  • 2
    • 0024282581 scopus 로고
    • Pituitary glycoprotein hormone oligosaccharides: Structure, synthesis, and function of the asparagine-linked oligosaccharides on lutrophin, follicotrophin and thyrotrophin
    • Baezinger J, Green ED (1988) Pituitary glycoprotein hormone oligosaccharides: Structure, synthesis, and function of the asparagine-linked oligosaccharides on lutrophin, follicotrophin and thyrotrophin. Biochem Biophys Acta 947:287-306
    • (1988) Biochem Biophys Acta , vol.947 , pp. 287-306
    • Baezinger, J.1    Green, E.D.2
  • 3
    • 0027131585 scopus 로고
    • Hypersecretion of luteinising hormone: A significant cause of infertility and miscarriage
    • Balen AH, Tan SL, Jacobs HS (1993) Hypersecretion of luteinising hormone: A significant cause of infertility and miscarriage. Br J Obstet Gynaecol 100:1082-1089
    • (1993) Br J Obstet Gynaecol , vol.100 , pp. 1082-1089
    • Balen, A.H.1    Tan, S.L.2    Jacobs, H.S.3
  • 4
    • 0033374832 scopus 로고    scopus 로고
    • Glycoprotein hormone structure-function and analog design
    • Boime I, Ben-Menahen D (1999) Glycoprotein hormone structure-function and analog design. Rec Prog Horm Res 54:271-289
    • (1999) Rec Prog Horm Res , vol.54 , pp. 271-289
    • Boime, I.1    Ben-Menahen, D.2
  • 5
    • 0020039615 scopus 로고
    • Enzyme immunoassay for factor VIII-related antigen
    • Cejka J (1982) Enzyme immunoassay for factor VIII-related antigen. Clin Chem 28:1356-1358
    • (1982) Clin Chem , vol.28 , pp. 1356-1358
    • Cejka, J.1
  • 6
    • 0025720537 scopus 로고
    • Contributions of arginines-43 and -94 of human choriogonadotropin beta to receptor binding and activation as determined by oligonucleotide-based mutagenesis
    • Chen F, Puett D (1991a) Contributions of arginines-43 and -94 of human choriogonadotropin beta to receptor binding and activation as determined by oligonucleotide-based mutagenesis. Biochemistry 30:10171-10175
    • (1991) Biochemistry , vol.30 , pp. 10171-10175
    • Chen, F.1    Puett, D.2
  • 7
    • 0025880137 scopus 로고
    • Delineation via site-directed mutagenesis of the carboxyl-terminal region of human choriogonadotropin beta required for subunit assembly and biological activity
    • Chen F, Puett D (1991b) Delineation via site-directed mutagenesis of the carboxyl-terminal region of human choriogonadotropin beta required for subunit assembly and biological activity. J Biol Chem 266:6904-6908
    • (1991) J Biol Chem , vol.266 , pp. 6904-6908
    • Chen, F.1    Puett, D.2
  • 8
    • 0025993392 scopus 로고
    • Role of the invariant aspartic acid 99 of human choriogonadotropin beta in receptor binding and biological activity
    • Chen F, Wang Y, Puett D (1991) Role of the invariant aspartic acid 99 of human choriogonadotropin beta in receptor binding and biological activity. J Biol Chem 266:19357-19361
    • (1991) J Biol Chem , vol.266 , pp. 19357-19361
    • Chen, F.1    Wang, Y.2    Puett, D.3
  • 9
    • 0017874586 scopus 로고
    • Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphrenylglycoluril
    • Fraker PJ, Speck JC Jr (1978) Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphrenylglycoluril. Biochem Biophys Res Commun 80:849-857
    • (1978) Biochem Biophys Res Commun , vol.80 , pp. 849-857
    • Fraker, P.J.1    Speck J.C., Jr.2
  • 11
    • 0018622915 scopus 로고
    • The effect of clomiphene on uncastrated and castrated male transsexuals
    • Goh HH, Chew PC, Karim SM, Ratnam SS (1979) The effect of clomiphene on uncastrated and castrated male transsexuals. Clin Endocrinol 11:249-255
    • (1979) Clin Endocrinol , vol.11 , pp. 249-255
    • Goh, H.H.1    Chew, P.C.2    Karim, S.M.3    Ratnam, S.S.4
  • 12
    • 0028558673 scopus 로고
    • Multiple promoter elements in the human chorionic gonadotropin beta subunit genes distinguish their expression from luteinizing hormone beta gene
    • Hollenberg AN, Pestell RG, Albanese C, Boers ME, Jameson JL (1994) Multiple promoter elements in the human chorionic gonadotropin beta subunit genes distinguish their expression from luteinizing hormone beta gene. Mol Cell Endocrinol 106:111-119
    • (1994) Mol Cell Endocrinol , vol.106 , pp. 111-119
    • Hollenberg, A.N.1    Pestell, R.G.2    Albanese, C.3    Boers, M.E.4    Jameson, J.L.5
  • 13
    • 0023712133 scopus 로고
    • Influence of serum luteinising hormone concentrations on ovulation, conception, and early pregnancy loss in polycystic ovary syndrome
    • Homburg R, Armar NA, Eshel A, Adams J, Jacobs HS (1988) Influence of serum luteinising hormone concentrations on ovulation, conception, and early pregnancy loss in polycystic ovary syndrome. BMJ 297:1024-1026
    • (1988) BMJ , vol.297 , pp. 1024-1026
    • Homburg, R.1    Armar, N.A.2    Eshel, A.3    Adams, J.4    Jacobs, H.S.5
  • 14
  • 15
    • 0027193414 scopus 로고
    • Amino/carboxyl-terminal deletion mutants of human choriogonadotropin beta
    • Huang J, Chen F, Puett D (1993b) Amino/carboxyl-terminal deletion mutants of human choriogonadotropin beta. J Biol Chem 268:9311-9315
    • (1993) J Biol Chem , vol.268 , pp. 9311-9315
    • Huang, J.1    Chen, F.2    Puett, D.3
  • 16
    • 0026800851 scopus 로고
    • Intracellular folding pathway of human chorionic gonadotropin beta subunit
    • Huth JR, Mountjoy K, Perini F, Ruddon RW (1992) Intracellular folding pathway of human chorionic gonadotropin beta subunit. J Biol Chem 267:8870-8879
    • (1992) J Biol Chem , vol.267 , pp. 8870-8879
    • Huth, J.R.1    Mountjoy, K.2    Perini, F.3    Ruddon, R.W.4
  • 17
    • 0036187866 scopus 로고    scopus 로고
    • A novel Ala(-3)Thr mutation in the signal peptide of human luteinizing hormone beta-subunit: Potential of the inositol phosphate signalling pathway and attenuation of the adenylate cyclase pathway by recombinant variant hormone
    • Jiang M, Lamminen T, Pakarinen P, Hellman J, Manna P, Herrera RJ, Huhtaniemi I (2002) A novel Ala(-3)Thr mutation in the signal peptide of human luteinizing hormone beta-subunit: Potential of the inositol phosphate signalling pathway and attenuation of the adenylate cyclase pathway by recombinant variant hormone. Mol Hum Reprod 8 (3): 201-212
    • (2002) Mol Hum Reprod , vol.8 , Issue.3 , pp. 201-212
    • Jiang, M.1    Lamminen, T.2    Pakarinen, P.3    Hellman, J.4    Manna, P.5    Herrera, R.J.6    Huhtaniemi, I.7
  • 18
    • 0018675127 scopus 로고
    • Structure and location of the O-glycosidic carbohydrate units of human chorionic gonadotropin
    • Kessler MJ, Mise T, Ghai RD, Bahl OP (1979) Structure and location of the O-glycosidic carbohydrate units of human chorionic gonadotropin. J Biol Chem 254:7909-7914
    • (1979) J Biol Chem , vol.254 , pp. 7909-7914
    • Kessler, M.J.1    Mise, T.2    Ghai, R.D.3    Bahl, O.P.4
  • 19
    • 0024550731 scopus 로고
    • Role of the beta 93-100 determinant loop sequence in receptor binding and biological activity of human luteinizing hormone and chorionic gonadotropin
    • Keutmann HT, Mason KA, Kitzmann K, Ryan RJ (1989) Role of the beta 93-100 determinant loop sequence in receptor binding and biological activity of human luteinizing hormone and chorionic gonadotropin. Mol Endocrinol 3:526-531
    • (1989) Mol Endocrinol , vol.3 , pp. 526-531
    • Keutmann, H.T.1    Mason, K.A.2    Kitzmann, K.3    Ryan, R.J.4
  • 20
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 21
    • 0035936874 scopus 로고    scopus 로고
    • A common genetic variant of luteinizing hormone: Relation to normal and aberrant pituitary-gonadal function
    • Lamminen T, Huhtaniemi I (2001) A common genetic variant of luteinizing hormone: Relation to normal and aberrant pituitary-gonadal function. Eur J Pharmacol 414:1-7
    • (2001) Eur J Pharmacol , vol.414 , pp. 1-7
    • Lamminen, T.1    Huhtaniemi, I.2
  • 23
    • 0031929585 scopus 로고    scopus 로고
    • A new molecular variant of luteinizing hormone associated with female infertility
    • Liao WX, Roy AC, Chan C, Arulkumaran S, Ratnam SS (1998) A new molecular variant of luteinizing hormone associated with female infertility. Fertil Steril 69:102-106
    • (1998) Fertil Steril , vol.69 , pp. 102-106
    • Liao, W.X.1    Roy, A.C.2    Chan, C.3    Arulkumaran, S.4    Ratnam, S.S.5
  • 24
    • 0024454312 scopus 로고
    • Mutagenesis and chimeric genes define determinants in the beta subunits of human chorionic gonadotropin and lutropin for secretion and assembly
    • Matzuk MM, Spangler MM, Camel M, Suganuma N, Boime I (1989) Mutagenesis and chimeric genes define determinants in the beta subunits of human chorionic gonadotropin and lutropin for secretion and assembly. J Cell Biol 109:1429-1438
    • (1989) J Cell Biol , vol.109 , pp. 1429-1438
    • Matzuk, M.M.1    Spangler, M.M.2    Camel, M.3    Suganuma, N.4    Boime, I.5
  • 25
    • 0343742651 scopus 로고    scopus 로고
    • Worldwide frequency of a common genetic variant of luteinizing hormone: An international collaborative research
    • Nilsson C, Pettersson K, Millar RP, Coerver KA, Matzuk MM, Huhtaniemi IT (1997) Worldwide frequency of a common genetic variant of luteinizing hormone: An international collaborative research. Fertil Steril 67:998-1004
    • (1997) Fertil Steril , vol.67 , pp. 998-1004
    • Nilsson, C.1    Pettersson, K.2    Millar, R.P.3    Coerver, K.A.4    Matzuk, M.M.5    Huhtaniemi, I.T.6
  • 26
    • 0019729482 scopus 로고
    • Glycoprotein hormones: Structure and function
    • Pierce JG, Parsons TF (1981) Glycoprotein hormones: Structure and function. Annu Rev Bioochem 50:465-495
    • (1981) Annu Rev Bioochem , vol.50 , pp. 465-495
    • Pierce, J.G.1    Parsons, T.F.2
  • 27
    • 0031926595 scopus 로고    scopus 로고
    • Molecular variants of luteinizing hormone in three populations of Southeast Asia
    • Ramanujam L, Liao WX, Roy AC, Ng SC, Ratnam SS (1998) Molecular variants of luteinizing hormone in three populations of Southeast Asia. Hum Hered 48:232-234
    • (1998) Hum Hered , vol.48 , pp. 232-234
    • Ramanujam, L.1    Liao, W.X.2    Roy, A.C.3    Ng, S.C.4    Ratnam, S.S.5
  • 29
    • 0034124344 scopus 로고    scopus 로고
    • Association of molecular variants of luteinizing hormone with male infertility
    • Ramanujam LN, Liao WX, Roy AC, Ng SC (2000) Association of molecular variants of luteinizing hormone with male infertility. Hum Reprod 15:925-928
    • (2000) Hum Reprod , vol.15 , pp. 925-928
    • Ramanujam, L.N.1    Liao, W.X.2    Roy, A.C.3    Ng, S.C.4
  • 30
    • 0028923296 scopus 로고
    • Targeted overexpression of luteiniziong hormone in transgenic mice leads to infertility, polycystic ovaries, and ovarian tumors
    • Risma KA, Clay CM, Nett TM, Wagner T, Yun J, Nilson JH (1995) Targeted overexpression of luteiniziong hormone in transgenic mice leads to infertility, polycystic ovaries, and ovarian tumors. Proc Natl Acad Sci U S A 92:1322-1326
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 1322-1326
    • Risma, K.A.1    Clay, C.M.2    Nett, T.M.3    Wagner, T.4    Yun, J.5    Nilson, J.H.6
  • 32
    • 0024813415 scopus 로고
    • Elimination of disulphide bonds affects assembly and secretion of the human chorionic gonadotropin â subunit
    • Suganuma N, Matzuk MM, Boime I (1989) Elimination of disulphide bonds affects assembly and secretion of the human chorionic gonadotropin â subunit. J Biol Chem 264:19302-19307
    • (1989) J Biol Chem , vol.264 , pp. 19302-19307
    • Suganuma, N.1    Matzuk, M.M.2    Boime, I.3
  • 33
    • 0028919465 scopus 로고
    • Secreening of the mutations in luteinizing hormone beta-subunit in patients with menstrual disorders
    • Suganuma N, Furui K, Furuhashi M, Asada Y, Kikkawa F, Tomoda Y (1995) Secreening of the mutations in luteinizing hormone beta-subunit in patients with menstrual disorders. Fertil Steril 63:989-995
    • (1995) Fertil Steril , vol.63 , pp. 989-995
    • Suganuma, N.1    Furui, K.2    Furuhashi, M.3    Asada, Y.4    Kikkawa, F.5    Tomoda, Y.6
  • 34
    • 0029669973 scopus 로고    scopus 로고
    • Effects of the mutations (Trp8 →Arg and Ile15 →Thr) in human luteinizing hormone (LH) beta-subunit on LH bioactivity in vitro and in vivo
    • Suganuma N, Furui K, Kikkawa F, Tomoda Y, Furuhashi M (1996) Effects of the mutations (Trp8 →Arg and Ile15 →Thr) in human luteinizing hormone (LH) beta-subunit on LH bioactivity in vitro and in vivo. Endocrinology 137:831-838
    • (1996) Endocrinology , vol.137 , pp. 831-838
    • Suganuma, N.1    Furui, K.2    Kikkawa, F.3    Tomoda, Y.4    Furuhashi, M.5
  • 35
    • 0021265260 scopus 로고
    • Evolution of the genes for the beta subunits of human chorionic gonadotrophin and luteinizing hormone
    • Talmadge K, Vamvakopoulos NC, Fiddes JC (1984) Evolution of the genes for the beta subunits of human chorionic gonadotrophin and luteinizing hormone. Nature 307:37-40
    • (1984) Nature , vol.307 , pp. 37-40
    • Talmadge, K.1    Vamvakopoulos, N.C.2    Fiddes, J.C.3
  • 36
    • 0033711033 scopus 로고    scopus 로고
    • Mutations of gonadotropins and gonadotropin receptors: Elucidating the physiology and pathophysiology of pituitary-gonadal function
    • Themmen APN, Huhtaniemi IT (2000) Mutations of gonadotropins and gonadotropin receptors: Elucidating the physiology and pathophysiology of pituitary-gonadal function. Endocr Rev 21:551-583
    • (2000) Endocr Rev , vol.21 , pp. 551-583
    • Themmen, A.P.N.1    Huhtaniemi, I.T.2
  • 37
    • 0026335545 scopus 로고
    • Hypogonadism caused by a single amino acid substitution in the beta subunit of luteinizing hormone
    • Weiss J, Axelrod L, Whitcomb RW, Harris PE, Crowley WF, Jameson JL (1992) Hypogonadism caused by a single amino acid substitution in the beta subunit of luteinizing hormone. N Engl J Med 326:179-183
    • (1992) N Engl J Med , vol.326 , pp. 179-183
    • Weiss, J.1    Axelrod, L.2    Whitcomb, R.W.3    Harris, P.E.4    Crowley, W.F.5    Jameson, J.L.6
  • 38
    • 0028773646 scopus 로고
    • Structure of human chorionic gonadotropin at 2.6 Å resolution from MAD analysis of the selenomethionyl protein
    • Wu H, Lustbader JW, Liu Y, Canfield RE, Hendrickson WA (1994) Structure of human chorionic gonadotropin at 2.6 Å resolution from MAD analysis of the selenomethionyl protein. Structure 2:545-558
    • (1994) Structure , vol.2 , pp. 545-558
    • Wu, H.1    Lustbader, J.W.2    Liu, Y.3    Canfield, R.E.4    Hendrickson, W.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.