Polyamine-mediated post-transcriptional regulation of COX-2

Biochimie

Volumn 84, Issue 8, 2002, Pages 815-819

  Parker, Michele Taylor ^a   Gerner, Eugene W ^a  

^a UNIVERSITY OF ARIZONA   (United States)

Author keywords

3 UTR; COX 2; eIF 5A

Indexed keywords

CYCLOOXYGENASE 2; EFLORNITHINE; INITIATION FACTOR 5A; MESSENGER RNA; POLYAMINE; PROTEIN; RNA; SPERMIDINE; EIF-5A; ENZYME INHIBITOR; INITIATION FACTOR; ISOENZYME; MEMBRANE PROTEIN; PROSTAGLANDIN SYNTHASE; PTGS2 PROTEIN, HUMAN; RNA BINDING PROTEIN;

APOPTOSIS; ARTICLE; CANCER; CANCER CELL; CANCER TISSUE; CARCINOGENESIS; CELL CYCLE; CELL GROWTH; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG MECHANISM; EMBRYO DEVELOPMENT; ENZYME INDUCTION; ENZYME REGULATION; ENZYME REPRESSION; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; MEDIATOR; ONCOGENE; PROTEIN DEPLETION; PROTEIN SYNTHESIS; RNA BINDING; RNA PROCESSING; RNA STRUCTURE; STEADY STATE; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE; 3' UNTRANSLATED REGION; BIOLOGICAL MODEL; BIOSYNTHESIS; CELL STRAIN CACO 2; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; PROMOTER REGION; PROTEIN PROCESSING;

3' UNTRANSLATED REGIONS; BASE SEQUENCE; BIOGENIC POLYAMINES; BLOTTING, NORTHERN; CACO-2 CELLS; CYCLOOXYGENASE 2; EFLORNITHINE; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; ISOENZYMES; MEMBRANE PROTEINS; MODELS, BIOLOGICAL; PEPTIDE INITIATION FACTORS; PROMOTER REGIONS (GENETICS); PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROTEIN PROCESSING, POST-TRANSLATIONAL; RNA, MESSENGER; RNA-BINDING PROTEINS;

EID: 0036703190     PISSN: 03009084     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-9084(02)01439-6     Document Type: Article

References (21)

1. F.L. Meyskens, E.W. Gerner, Development of difluoromethylornithine (DFMO) as a chemoprevention agent, Clin. Cancer Res. 5 (1999) 945-951.
2. S. Watanabe, K. Kusama-Eguchi, H. Kobayashi, K. Igarashi, Estimation of polyamine binding to macromolecules and ATP in bovine lymphocytes and rat liver, J. Biol. Chem. 266 (1991) 20803-20809.
3. M.H. Park, H.L. Cooper, J.E. Folk, Identification of hypusine, an unusual amino acid, in a protein from human lymphocytes and of spermidine as its biosynthetic precursor, Proc. Natl. Acad. Sci. USA 78 (1981) 2869-2873.
4. K.Y. Chen, An 18 000-dalton protein metabolically labeled by polyamines in various mammalian cell lines, Biochim. Biophys. Acta 756 (1983) 395-402.
5. D. Zuk, A. Jacobson, A single amino acid substitution in yeast eIF-5A results in mRNA stabilization, Embo J. 17 (1998) 2914-2925.
6. O. Schatz, M. Oft, C. Dascher, M. Schebesta, O. Rosorius, H. Jaksche, M. Dobrovnik, D. Bevec, J. Hauber, Interaction of the HIV-1 rev cofactor eukaryotic initiation factor 5A with ribosomal protein L5, Proc. Natl. Acad. Sci. USA 95 (1998) 1607-1612.
7. O. Rosorius, B. Reichart, F. Kratzer, P. Heger, M.C. Dabauvalle, J. Hauber, Nuclear pore localization and nucleocytoplasmic transport of eIF-5A: evidence for direct interaction with the export receptor CRM1, J. Cell Sci. 112 (1999) 2369-2380.
8. A. Xu, K.Y. Chen, Hypusine is required for a sequence-specific interaction of eukaryotic initiation factor 5A with postsystematic evolution of ligands by exponential enrichment RNA, J. Biol. Chem. 276 (2001) 2555-2561.
9. C.E. Eberhart, R.J. Coffey, A. Radhika, F.M. Giardiello, S. Ferrenbach, R.N. DuBois, Up-regulation of cyclooxygenase-2 gene expression in human colorectal adenomas and adenocarcinomas, Gastroenterology 107 (1994) 1183-1188.
10. H. Sheng, J. Shao, S.C. Kirkland, P. Isakson, R.J. Coffey, J. Morrow, R.D. Beauchamp, R.N. DuBois, Inhibition of human colon cancer cell growth by selective inhibition of cyclooxygenase-2, J. Clin. Invest. 99 (1997) 2254-2259.
11. H. Sheng, J. Shao, J.D. Marrow, R.D. Beauchamp, R.N. DuBois, Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells, Cancer Res. 58 (1998) 362-366.
12. M.T. Taylor, K.R. Lawson, N.A. Ignatenko, S.E. Marek, D.E. Stringer, B.A. Skovan, E.W. Gerner, Sulindac sulfone inhibits K-ras-dependent cyclooxygenase-2 expression in human colon cancer cells, Cancer Res. 60 (2000) 6607-6610.
13. K.R. Lawson, N.A. Ignatenko, G.A. Piazza, H. Cui, E.W. Gerner, Influence of K-ras activation on the survival responses of Caco-2 cells to the chemopreventive agents sulindac and difluoromethylornithine, Cancer Epidemiol. Biomarkers Prev. 9 (2000) 1155-1162.
14. H. Inoue, T. Nanayama, S. Hara, C. Yokoyama, T. Tanabe, The cyclic AMP response element plays an essential role in the expression of the human prostaglandin-endoperoxide synthase 2 gene in differentiated U937 monocytic cells, FEBS Lett. 350 (1994) 51-54.
15. D.A. Dixon, C.D. Kaplan, T.M. McIntyre, G.A. Zimmerman, S.M. Prescott, Post-transcriptional control of cyclooxygenase-2 gene expression. The role of the 3′-untranslated region, J. Biol. Chem. 275 (2000) 11750-11757.
16. H. Sheng, J. Shao, D.A. Dixon, C.S. Williams, S.M. Prescott, R.N. DuBois, R.D. Beauchamp, Transforming growth factor-beta1 enhances Ha-ras-induced expression of cyclooxygenase-2 in intestinal epithelial cells via stabilization of mRNA, J. Biol. Chem. 275 (2000) 6627-6635.
17. S.J. Cok, A.R. Morrison, The 3′-untranslated region of murine cyclooxygenase-2 contains multiple regulatory elements that alter message stability and translational efficiency, J. Biol. Chem. 276 (2001) 23179-23185.
18. A.R. Simoneau, E.W. Gerner, M. Phung, C.E. McLaren, F.L. Meyskens Jr, Alpha-difluoromethylornithine and polyamine levels in the human prostate: results of a phase IIa trial, J. Natl. Cancer Inst. 93 (2001) 57-59.
19. H. Sheng, C.S. Williams, J. Shao, P. Liang, R.N. DuBois, R.D. Beauchamp, Induction of cyclooxygenase-2 by activated Ha-ras oncogene in Rat-1 fibroblasts and the role of mitogen-activated protein kinase pathway, J. Biol. Chem. 273 (1998) 22120-22127.
20. H. Sheng, J. Shao, R.N. Dubois, K-Ras-mediated increase in cyclooxygenase-2 mRNA stability involves activation of the protein kinase B1, Cancer Res. 61 (2001) 2670-2675.
21. U.M. Wallon, L.R. Shassetz, A.E. Cress, G.T. Bowden, E.W. Gerner, Polyamine-dependent expression of the matrix metalloproteinase matrilysin in a human colon cancer-derived cell line, Mol. Carcinog. 11 (1994) 138-144.