A novel method for monitoring response to chemotherapy based on the detection of circulating cancer cells: A case report

Journal of Chemotherapy

Volumn 14, Issue 4, 2002, Pages 412-416

  Aquino, Angelo ^a   Prete, S P ^a   Balduzzi, A ^a   Fossile, E ^a   Formica, V ^a   Torino, F ^a   Bonmassar, L ^a   Di Giacomo, A ^a   Cappelletti, D ^a   Cardillo, A ^a   Graziani, G ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

CEA; Immunomagnetic isolation; RT PCR; Staurosporine

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; EPITHELIAL MEMBRANE ANTIGEN; FLUOROURACIL; FOLINIC ACID; MESSENGER RNA; MONOCLONAL ANTIBODY; STAUROSPORINE;

ADULT; ANTIGEN DETECTION; ARTICLE; BLOOD SAMPLING; CANCER CHEMOTHERAPY; CANCER DIAGNOSIS; CANCER STAGING; CASE REPORT; CELL COUNT; CLINICAL FEATURE; COLON CARCINOMA; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DISEASE COURSE; FEMALE; FOLLOW UP; HUMAN; HUMAN CELL; LIVER METASTASIS; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; RNA TRANSCRIPTION; TREATMENT OUTCOME;

EID: 0036693979     PISSN: 1120009X     EISSN: None     Source Type: Journal    
DOI: 10.1179/joc.2002.14.4.412     Document Type: Article

References (18)

1. Cancer statistics, 2000
2. Chemotherapy of advanced cancer of the colon and rectum
3. New surgical treatments for recurrent colorectal cancer
4. Fluorouracil plus levamisole as effective adjuvant therapy after resection of stage III colon carcinoma: A final report
5. Quantitative analysis of CEA expression in colorectal adenocarcinoma and serum: Lack of correlation
6. Adenocarcinoma of the colon and rectum
7. Detection of blood-borne cells in colorectal cancer patients by nested reverse transcription-polymerase chain reaction for carcinoembryonic antigen messenger RNA: Longitudinal analyses and demonstration of its potential importance as an adjunct to multiple serum markers
8. Increased detection of circulating tumor cells in the blood of colorectal carcinoma patients using two reverse transcription-PCR assays and multiple blood samples
9. Prognostic significance of reverse transcriptase-polymerase chain reaction measurement of carcinoembryonic antigen mRNA levels in tumor drainage blood and peripheral blood of patients with colorectal carcinoma
10. Detection of circulating tumor cells in patients with gastrointestinal tract cancer using RT-PCR and its clinical implications
11. Limitations of specific reverse-transcriptase polymerase chain reaction markers in the detection of metastases in the lymph nodes and blood of breast cancer patients
12. Limitations of the reverse transcription-polymerase chain reaction method for the detection of carcinoembryonic antigen-positive tumor cells in peripheral blood
13. Immunobead RT-PCR versus regular RT-PCR amplification of CEA mRNA in peripheral blood
14. Staurosporine increases carcinoembryonic antigen expression in a human colon cancer cell line
15. Pharmacological modulation of carcinoembryonic antigen in human cancer cells: Studies with staurosporine
16. Cloning of the complete gene for carcinoembryonic antigen: Analysis of its promoter indicates a region conveying cell type-specific expression
17. Circulating tumor cell clusters in the peripheral blood of colorectal cancer patients
18. Treatment of peripheral blood with staurosporine increases detection of circulating carcinoembryonic antigen positive tumor cells