Antinociceptive effects of 1-acyl-4-dialkylaminopiperidine and 1-alkyl-4-dialkylaminopiperidine in mice: Structure-activity relation study of matrine-type alkaloids

Biological and Pharmaceutical Bulletin

Volumn 25, Issue 8, 2002, Pages 1030-1034

  Kobashi, Seiichi ^a   Kubo, Hajime ^a   Yamauchi, Takayasu ^a   Higashiyama, Kimio ^a  

^a HOSHI UNIVERSITY   (Japan)

Author keywords

Antinociception; Matrine; Structure activity relationship

Indexed keywords

(1 BENZYLPIPERIDIN 4 YL)DIMETHYLAMINE; (1 ETHYLPIPERIDIN 4 YL)DIBUTYLAMINE; (4 DIBUTYLAMINOPIPERIDIN 1 YL)PENTANE; (4 DIMETHYLAMINOPIPERIDIN 1 YL)PENTANE; 1 ACYL 4 AMINOPIPERIDINE; ACETIC ACID; ANTINOCICEPTIVE AGENT; PIPERIDINE DERIVATIVE; UNCLASSIFIED DRUG; ALKALOID; ANALGESIC AGENT; MATRINE; QUINOLIZINE DERIVATIVE;

ABDOMEN; ANTINOCICEPTION; ARTICLE; DRUG POTENCY; DRUG SYNTHESIS; MALE; MOUSE; MUSCLE CONTRACTION; NONHUMAN; STRUCTURE ACTIVITY RELATION; ANIMAL; CHEMISTRY; DOSE RESPONSE; DRUG EFFECT; INSTITUTE FOR CANCER RESEARCH MOUSE; METHODOLOGY; PAIN ASSESSMENT;

ALKALOIDS; ANALGESICS; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; MICE; MICE, INBRED ICR; PAIN MEASUREMENT; PIPERIDINES; QUINOLIZINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0036692150     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.25.1030     Document Type: Article

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