Cytotoxin of Helicobacter pylori promotes IL-8 secretion of gastric mucosa in vitro

World Chinese Journal of Digestology

Volumn 10, Issue 8, 2002, Pages 907-911

  Xu, Ke Qiang ^a   Zhang, Wan Dai ^a   Wang, Ji De ^a   Li, Zi Xu ^a   Zhou, Dain Yuan ^a   Zhang, Ya Li ^a   Huang, Wen Feng ^a   Jiang, Bo ^a   Sun, Yong ^a  

^a Department of Orthopaedics   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; CYTOTOXIN; GENE PRODUCT; INTERLEUKIN 6; INTERLEUKIN 8; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VACUOLATING TOXIN;

ADULT; ARTICLE; BIOPSY TECHNIQUE; CANCER GRADING; CHRONIC GASTRITIS; CLINICAL ARTICLE; CORRELATION ANALYSIS; CYTOKINE PRODUCTION; CYTOTOXICITY; DUODENUM ULCER; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HELICOBACTER PYLORI; HUMAN; IMMUNOPATHOGENESIS; MALE; PROTEIN CONTENT; STAINING; STOMACH ANTRUM; STOMACH MUCOSA;

EID: 0036689431     PISSN: 10093079     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (45)

1. Helicobacter pylori and gastric mucosal cytokines: Evidence that CagA-positive strains are more virulent
2. Immunopathogenesis of Helicobacter pylori infection
3. Relationship of type T-H1/T-H2 cytokines in Hp infection gastric diseases
4. Proinflammatory factors during Helicobacter pylori infection
5. Helicobacter pylori induces an array of pro-inflammatory cytokines in human gastric epithelial cells: Quantification of mRNA for interleukin-8, -1 alpha/beta, granulocyte-macrophage colony-stimulating factor, monocyte chemoattractant protein-1 and tumour necrosis factor-alpha
6. Interleukin-8 activity correlates with histological severity in Helicobacter pylori-associated antral gastritis
7. Mucosal interleukin-8 and Helicobacter pylori-associated gastroduodenal disease
8. Parasitism by the "slow" bacterium Helicobacter pylori leads to altered gastric homeostasis and neoplasia
9. Gastric mucosal interleukin-8 and IL-8 antibody concentrations related to prevailing Helicobacter pylori infections. A Danish-Albanian study
10. Relationship of TGF-b1 and Helicobacter pylori infection in gastric mucosa
11. Relationship between mucosal levels of Helicobacter pylorispecific IgA, interleukin-8 and gastric inflammation
12. Induction of chemokine and cytokine responses by Helicobacter pylori in human stomach explants
13. Coexpression of interleukin-8 and inducible nitric oxide synthase in gastric mucosa infected with cagA+ Helicobacter pylori
14. Increased cytokine production by gastric mucosa in patients with Helicobacter pylori infection
15. Interactions among gastric somatostatin, interleukin-8 and mucosal inflammation in Helicobacter pylori-positive peptic ulcer patients
16. Mechanism for Helicobacter pylori stimulation of interleukin-8 production in a gastric epithelial cell line (MKN 28): Roles of mitogen-activated protein kinase and interleukin-1beta
17. Mucosal chemokine activity in Helicobacter pylori infection
18. Interleukin-8 expression by human neutrophils activated by Helicobacter pylori soluble proteins
19. Gastric corpus IL-8 concentration and neutrophil infiltration in duodenal ulcer patients
20. Increased gastric production of interleukin-8 and tumour necrosis factor in patients with Helicobacter pylori infection
21. Mucosal tumor necrosis factor-alpha, interleukin-1 beta, and interleukin-8 production in patients with Helicobacter pylori infection
22. Helicobacter pylori induces interleukin-8 expression in endothelial cells and the signal pathway is protein tyrosine kinase dependent
23. Enhanced mucosal expression of interleukin-6 mRNA but not of interleukin-8 mRNA at the margin of gastric ulcer in Helicobacter pylori-positive gastritis
24. Molecular analysis of suppression of interleukin-8 production by rebamipide in Helicobacter pylori-stimulated gastric cancer cell lines
25. Helicobacter pylori-dependent ceramide production may mediate increased interleukin 8 expression in human gastric cancer cell lines
26. Mechanisms involved in Helicobacter pylori-induced interleukin-8 production by a gastric cancer cell line, MKN45
27. Helicobacter pylori-induced expression of interleukin-8 and cyclooxygenase-2 in AGS gastric epithelial cells: Mediation by nuclear factor-kappaB
28. Multiple genes in the left half of the cag pathogenicity island of Helicobacter pylori are required for tyrosine kinase-dependent transcription of interleukin-8 in gastric epithelial cells
29. Interleukin-8 production in primary cultures of human gastric epithelial cells induced by Helicobacter pylori
30. Implication of the structure of the Helicobacter pylori cag pathogenicity island in induction of interleukin-8 secretion
31. Helicobacter pylori water extract induces interleukin-8 production by gastric epithelial cells
32. Relationship between interleukin-8 levels and myeloperoxidase activity in human gastric mucosa
33. Water extract of Helicobacter pylori stimulates interleukin-8 secretion by a human gastric epithelial cell line (JR-St) through protein tyrosine phosphorylation
34. The interrelationship between cytotoxin-associated gene A, vacuolating cytotoxin, and Helicobacter pylori-related diseases
35. Role of adherence in interleukin-8 induction in Helicobacter pylori-associated gastritis
36. Interleukin-8 response of gastric epithelial cell lines to Helicobacter pylori stimulation in vitro
37. Coccoid and spiral Helicobacter pylori differ in their abilities to adhere to gastric epithelial cells and induce interleukin-8 secretion
38. Analysis of interleukin-8 secretion induced by Helicobacter pylori from the gastric epithelial cell line MKN45: A mechanism independent of the intensity of cytotoxicity
39. Pathogenic implications of interleukin-8 activity and bacterial phenotype in antral gastritis associated with Helicobacter pylori
40. Differential normalization of mucosal interleukin-8 and interleukin-6 activity after Helicobacter pylori eradication
41. Modulation of Helicobacter pylori induced interleukin-8 synthesis in gastric epithelial cells mediated by cag PAI encoded VirD4 homologue
42. Helicobacter pylori cag pathogenicity island is associated with enhanced interleukin-8 expression in human gastric mucosa
43. The transcription of interleukin-8 in gastric epithelial cells by Helicobacter pylori strains in Chinese
44. Vacuolating cytotoxin (vacA) alleles of Helicobacter pylori comprise two geographically widespread types, m1 and m2, and have evolved through limited recombination
45. Proinflammatory activation of neutrophils and monocytes by Helicobacter pylori is not associated with cagA, vacA or picB genotypes