Monte Carlo simulation of hyaluronidase reaction involving hydrolysis, transglycosylation and condensation

Biochemical Journal

Volumn 365, Issue 3, 2002, Pages 701-705

  Nakatani, Hiroshi ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Enzyme kinetics; Enzyme mechanism; Hyaluronan; Probabilistic model

Indexed keywords

ALGORITHMS; CONDENSATION; HYDROLYSIS; MATHEMATICAL MODELS; MONTE CARLO METHODS; PROBABILITY; SUBSTRATES; SUGARS;

PROBABILISTIC CYCLES;

ENZYMES;

HYALURONIC ACID; HYALURONIDASE; OLIGOSACCHARIDE; POLYMER;

ALGORITHM; ARTICLE; CATTLE; ENZYME ACTIVE SITE; ENZYME GLYCOSYLATION; ENZYME KINETICS; ENZYME MECHANISM; MONTE CARLO METHOD; POLYMERIZATION; PRIORITY JOURNAL; PROBABILITY; PROTEIN HYDROLYSIS; STATISTICAL MODEL;

ALGORITHMS; ANIMALS; CATTLE; COMPUTER SIMULATION; GLYCOSYLATION; HYALURONIC ACID; HYALURONOGLUCOSAMINIDASE; HYDROLYSIS; MALE; MATHEMATICS; MONTE CARLO METHOD; TESTIS;

BOS TAURUS; BOVINAE;

EID: 0036684594     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20011769     Document Type: Article

References (14)

1. Hyaluronidases
2. Hyaluronidases - A group of neglected enzymes
3. Mechanism of action of bovine testicular hyaluronidase
4. Hyaluronidases in tissue invasion
5. Enzymatic reconstruction of glycosaminoglycan oligosaccharide chains using the transglycosylation reaction of bovine testicular hyaluronidase
6. Enzymatic reconstruction of a hybrid glycosaminoglycan containing 6-sulfated, 4-sulfated, and unsulfated N-acetylgalactosamine
7. Enzymatic reconstruction of dermatan sulfate
8. Kinetic and mechanistic studies with bovine testicular hyaluronidase
9. Monte Carlo simulation of multiple attack mechanism of α-amylase
10. Monte Carlo simulation of multiple attack mechanism of β-amylase-catalyzed reaction
11. Monte Carlo simulation of 4-α-glucanotransferase reaction
12. Analysis of glycosidase-catalyzed transglycosylation reaction using probabilistic model
13. Characterization of hydrolysis and transglycosylation by testicular hyaluronidase using ion-spray mass spectrometry
14. New characteristic signatures from time dependent static light scattering during polymer depolymerization, with application to proteoglycan subunit degradation