The total influenza vaccine failure of 1947 revisited: Major intrasubtypic antigenic change can explain failure of vaccine in a post-World War II epidemic

Proceedings of the National Academy of Sciences of the United States of America

Volumn 99, Issue 16, 2002, Pages 10748-10752

  Kilbourne, Edwin D ^a,c   Smith, Catherine ^b   Brett, Ian ^a   Pokorny, Barbara A ^a   Johansson, Bert ^a   Cox, Nancy ^b  

^a NEW YORK MEDICAL COLLEGE   (United States)

^b NATIONAL CENTER FOR IMMUNIZATION AND RESPIRATORY DISEASES   (United States)

^c NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INFLUENZA VACCINE; VIRUS ANTIGEN; VIRUS HEMAGGLUTININ; VIRUS SIALIDASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ANTIGENIC VARIATION; ARTICLE; CONTROLLED STUDY; CROSS REACTION; EPIDEMIC; FEMALE; IMMUNOGENICITY; INFLUENZA; INFLUENZA VACCINATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; STRAIN DIFFERENCE; TREATMENT FAILURE; VACCINATION; VIRUS MUTATION; VIRUS STRAIN;

ANIMALS; ANTIGENIC VARIATION; ANTIGENS, VIRAL; BASE SEQUENCE; CELL LINE; CROSS REACTIONS; DISEASE MODELS, ANIMAL; DISEASE OUTBREAKS; DNA, VIRAL; DOGS; FEMALE; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; HUMANS; INFLUENZA A VIRUS; INFLUENZA VACCINES; INFLUENZA, HUMAN; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; NEURAMINIDASE; SEQUENCE ANALYSIS, DNA; SEQUENCE ANALYSIS, PROTEIN; TREATMENT FAILURE; VACCINES, INACTIVATED; WAR; WORLD HEALTH;

ANIMALIA; INFLUENZA A VIRUS;

EID: 0036678093     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.162366899     Document Type: Article

References (23)