Diltiazem heals glyceryl trinitrate-resistant chronic anal fissures: A prospective study

Diseases of the Colon and Rectum

Volumn 45, Issue 8, 2002, Pages 1091-1095

  Jonas, Marion ^a   Speake, William ^a   Scholefield, John H ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Anal fissure; Chemical sphincterotomy; Diltiazem; Treatment

Indexed keywords

DILTIAZEM; GLYCERYL TRINITRATE;

ADULT; AFFECTIVE NEUROSIS; AGED; ANUS FISSURE; ANUS PRURITUS; ARTICLE; CLINICAL ARTICLE; CLINICAL FEATURE; DROWSINESS; DRUG EFFICACY; DRUG TOLERABILITY; FEMALE; FOLLOW UP; HEADACHE; HUMAN; MALE; MANOMETRY; SCORING SYSTEM; TREATMENT OUTCOME; VISUAL ANALOG SCALE; WOUND HEALING;

ADMINISTRATION, TOPICAL; ADULT; AGED; AGED, 80 AND OVER; CALCIUM CHANNEL BLOCKERS; CHRONIC DISEASE; DILTIAZEM; FEMALE; FISSURE IN ANO; GELS; HUMANS; MALE; MIDDLE AGED; NITROGLYCERIN; OINTMENTS; PROSPECTIVE STUDIES; STATISTICS, NONPARAMETRIC; TREATMENT OUTCOME; VASODILATOR AGENTS; WOUND HEALING;

EID: 0036677984     PISSN: 00123706     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10350-004-6365-z     Document Type: Article

References (16)

1. Randomised controlled trial shows that glyceryl trinitrate heals anal fissures, higher doses are not more effective, and there is a high recurrence rate
2. Glyceryl trinitrate ointment for the treatment of chronic anal fissure: Results of a placebo-controlled trial and long-term follow-up
3. A randomised, prospective, double-blind, placebo-controlled trial of glyceryl trinitrate ointment in the treatment of anal fissure
4. One hundred cases of anal fissure treated with botulin toxin: Early and long-term results
5. A comparison of injections of botulinum toxin and topical nitroglycerin ointment for the treatment of chronic anal fissure
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8. Topical diltiazem ointment in the treatment of chronic anal fissure
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13. Relationship between anal pressure and anodermal blood flow: The vascular pathogenesis of anal fissures
14. Internal sphincter spasm in anal fissure
15. Topical 0.2 percent glyceryl trinitrate ointment has a short-lived effect on resting anal pressure
16. Quality of life in patients with benign anorectal disorders