Mcl-1 mediates cytokine deprivation induced apoptosis of human myeloma cell line XG-7

Chinese Medical Journal

Volumn 115, Issue 8, 2002, Pages 1241-1243

  Song, Lun ^a   Li, Yan ^a   Sun, Yingxun ^a   Shen, Beifen ^a  

^a BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

Author keywords

Apoptosis; Bcl 2; Bcl xL; IL 6; Mcl 1; Myeloma

Indexed keywords

CYTOKINE; INTERLEUKIN 6; PROPIDIUM IODIDE; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN MCL 1; BCL2L1 PROTEIN, HUMAN; MCL1 PROTEIN; PROTEIN BCL X; TUMOR PROTEIN;

APOPTOSIS; ARTICLE; CELL NUCLEUS; CELL STIMULATION; CONTROLLED STUDY; DOWN REGULATION; FLOW CYTOMETRY; HUMAN; IMMUNOBLOTTING; MONITORING; MULTIPLE MYELOMA; MYELOMA CELL; PROTEIN EXPRESSION; CELL CULTURE; PATHOLOGY; PHYSIOLOGY;

APOPTOSIS; HUMAN; INTERLEUKIN-6; MULTIPLE MYELOMA; NEOPLASM PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; SUPPORT, NON-U.S. GOV'T; TUMOR CELLS, CULTURED; BCL-X PROTEIN; HUMANS;

EID: 0036676707     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Multiple myeloma: Increasing evidence for a multistep transformation process
2. The Bcl-2 protein family: Arbiters of cell survival
3. Bcl-x, a Bcl-2-related gene that functions as a dominant regulator of apoptotic cell death
4. Expression of the Bcl-2 homologue Mcl-1 correlates with survival of perpheral blood B lyphocytes
5. IL-6-indued inhibition of multiple myeloma cell apoptosis: Support for the hypothesis that protection is mediated via inhibition of JNK/SARK pathway
6. Signal transduction and biological function of IL-6 in a human myeloma cell line-XG-7
7. L are co-regulated by IL-6 in human myeloma cells