Expression of recombinant adeno-associated virus in the brain of rats with a focal embolic stroke via carotid artery

Chinese Medical Journal

Volumn 115, Issue 8, 2002, Pages 1170-1174

  Han, Zongchao ^a,b   Zhang, Suming ^a   Li, Hongwei ^a   Ruan, Xuzhong ^a   Xiao, Xiao ^a   Wang, Tao ^a   Wang, Daowen ^a  

^a Tongji Hospital   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Adeno associated virus; Cerebral ischemia; Gene therapy; Rat

Indexed keywords

BETA GALACTOSIDASE; CALCIUM PHOSPHATE; FIBRIN; PLASMID VECTOR;

ADENO ASSOCIATED VIRUS; ANIMAL TISSUE; ARTICLE; ARTIFICIAL EMBOLISM; BLOOD BRAIN BARRIER; BRAIN EMBOLISM; BRAIN INFARCTION; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CAROTID ARTERY; CELL COUNT; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; EXPRESSION VECTOR; GENE CONSTRUCT; GENE EXPRESSION; GENETIC TRANSFECTION; MALE; NONHUMAN; RAT; STROKE; TISSUE SECTION; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY; VIRUS EXPRESSION; VIRUS RECOMBINANT; ANIMAL; BRAIN; GENE THERAPY; GENE VECTOR; GENETICS; SPRAGUE DAWLEY RAT; VIROLOGY;

ANIMAL; BLOOD-BRAIN BARRIER; BRAIN; CAROTID ARTERIES; CEREBROVASCULAR ACCIDENT; DEPENDOVIRUS; GENE THERAPY; GENETIC VECTORS; INTRACRANIAL EMBOLISM; MALE; RATS; RATS, SPRAGUE-DAWLEY; SUPPORT, NON-U.S. GOV'T; ANIMALS;

EID: 0036674988     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

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2. An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3
3. Cerebral infarction in rats using homologous blood emboli: Development of a new experimental model
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5. Gene delivery to skeletal muscle results in sustained expression and systemic delivery of a therapeutic protein
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7. The principles of gene therapy for the nervous system
8. Direct in vivo gene transfer into the coronary and peripheral vasculatures of the intact dog