Brain extraction of 4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]pyridinium ion (HPP+), a neurotoxic metabolite of haloperidol: Studies using [3H]HPP+

Japanese Journal of Pharmacology

Volumn 89, Issue 4, 2002, Pages 426-428

  Kawashima, Hidekazu ^a   Iida, Yasuhiko ^a   Kitamura, Youji ^a   Kiyono, Yasushi ^a   Magata, Yasuhiro ^a   Saji, Hideo ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Blood brain barrier; Dopaminergic neuronal toxicity; HPP+

Indexed keywords

4 (4 CHLOROPHENYL) 1 [4 (4 FLUOROPHENYL) 4 OXYBUTYL]PYRIDINIUM ION H 3; BUTANOL; DRUG METABOLITE; HALOPERIDOL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN; BRAIN INJURY; DOPAMINERGIC NERVE CELL; DRUG BRAIN LEVEL; DRUG ISOLATION; DRUG SYNTHESIS; DRUG UPTAKE; LIVER MICROSOME; MALE; MEMBRANE PERMEABILITY; MOUSE; NEUROTOXICITY; NONHUMAN; RAT;

EID: 0036672269     PISSN: 00215198     EISSN: None     Source Type: Journal    
DOI: 10.1254/jjp.89.426     Document Type: Article

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