F-10748 A1, A2, B1, B2, C1, C2, D1, and D2, novel papulacandins

Journal of Antibiotics

Volumn 55, Issue 8, 2002, Pages 758-763

  Ohyama, Takao ^a   Iwadate Kurihara, Yuko ^a   Hosoya, Tsuyoshi ^a   Ishikawa, Tomio ^a   Miyakoshi, Shunichi ^a   Hamano, Kiyoshi ^a   Inukai, Masatoshi ^a  

^a DAIICHI SANKYO CO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1,3 BETA GLUCAN SYNTHASE; ANTIFUNGAL AGENT; CARBON 13; CHAETIACANDIN; ENZYME INHIBITOR; F 10748; PAPULACANDIN A; PAPULACANDIN B; PAPULACANDIN C; PAPULACANDIN D; PAPULACANDIN DERIVATIVE; PROTON; UNCLASSIFIED DRUG; 1,3-BETA-GLUCAN SYNTHASE; AMINOGLYCOSIDE; ANTIINFECTIVE AGENT; GLUCOSYLTRANSFERASE; MEMBRANE PROTEIN; PAPULACANDINS; SCHIZOSACCHAROMYCES POMBE PROTEIN;

ANTIFUNGAL ACTIVITY; ASPERGILLUS FUMIGATUS; CANDIDA ALBICANS; CANDIDA PARAPSILOSIS; CANDIDA TROPICALIS; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; CRYPTOCOCCUS NEOFORMANS; DRUG ISOLATION; DRUG STRUCTURE; DRUG SYNTHESIS; FUNGAL STRAIN; FUNGUS CULTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NOTE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; ARTICLE; BIOSYNTHESIS; CHEMISTRY; DEUTEROMYCETES; DRUG ANTAGONISM; DRUG EFFECT; FUNGUS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PINE; PLANT LEAF;

AMINOGLYCOSIDES; ANTI-BACTERIAL AGENTS; ANTIBIOTICS, ANTIFUNGAL; FUNGI; GLUCOSYLTRANSFERASES; MAGNETIC RESONANCE SPECTROSCOPY; MEMBRANE PROTEINS; MICROBIAL SENSITIVITY TESTS; MITOSPORIC FUNGI; PINUS; PLANT LEAVES; SCHIZOSACCHAROMYCES POMBE PROTEINS;

EID: 0036671348     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.55.758     Document Type: Note

References (9)

1. Papulacandins, a new family of antibiotics with antifungal activity. I. Fermentation, isolation, chemical and biologiqal characterization of papulacandins A, B, C, D and E
2. Papulacandins, a new family of antibiotics with antifungal activity. Structures of papulacandins A, B, C and D
3. Chaetiacandin, a novel papulacandin. I. Fermentation, isolation and characterization
4. Chaetiacandin, a novel papulacandin. II. Structure determination
5. Arborcandin A, B, C, D, E, and F, novel 1,3-β-glucan synthase inhibitors: Production and biological activity
6. L-687,781, a new member of the papulacandin family of β-1,3-D-glucan synthesis inhibitors. I. Fermentation, isolation, and biological activity
7. BU-4794F, a new β-1,3-glucan synthase inhibitor
8. In vitro antifungal activities and in vivo efficacies of 1.3-β-D-glucan synthesis inhibitors L-671,329, L-646,991, tetrahydroechinocandin B, and L-687,781, a papulacandin