Odor discrimination by G protein-coupled olfactory receptors

Microscopy Research and Technique

Volumn 58, Issue 3, 2002, Pages 135-141

  Touhara, Kazushige ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Calcium imaging; cAMP; G protiens; Odorant; Olfaction; Olfactory neuron; Olfactory receptor

Indexed keywords

CALCIUM; CODES (SYMBOLS); GENES; NEURONS; PROTEINS;

CALCIUM IMAGING; CAMP; G PROTEIN; G PROTIENS; ODORANT; ODORANT RECEPTORS; OLFACTION; OLFACTORY BULBS; OLFACTORY NEURON; OLFACTORY RECEPTORS;

ODORS;

G PROTEIN COUPLED RECEPTOR; CALCIUM; CYCLIC AMP; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL CELL; ARTICLE; CHEMOSENSITIVITY; CONCENTRATION RESPONSE; MODEL; MOLECULAR CLONING; NONHUMAN; ODOR; OLFACTORY BULB; OLFACTORY DISCRIMINATION; OLFACTORY EPITHELIUM; OLFACTORY RECEPTOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RECEPTIVE FIELD; RECEPTOR INTRINSIC ACTIVITY; SIGNAL DETECTION; SIGNAL TRANSDUCTION; SMELLING; VERTEBRATE; ANIMAL; CHEMISTRY; CYTOLOGY; GENETICS; HUMAN; METABOLISM; PHYSIOLOGY; REVIEW; STRUCTURE ACTIVITY RELATION;

VERTEBRATA;

ANIMALS; CALCIUM; CYCLIC AMP; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; HUMANS; ODORS; OLFACTORY RECEPTOR NEURONS; RECEPTORS, ODORANT; SIGNAL TRANSDUCTION; SMELL; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0036668321     PISSN: 1059910X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jemt.10131     Document Type: Article

References (78)

1. Towards a common strategy for transducing olfactory information
2. The molecular receptive range of an odorant receptor
3. Neurobiology of the Caenorhabditis elegans genome
4. The molecular parameters of olfactory response
5. Mice deficient in Golf are anosmic
6. Olfactory receptor gene cluster on human chromosome 17: Possible duplication of an ancestral receptor repertoire
7. Calcium controls signaling in olfaction
8. Second messenger signalling in olfaction
9. General anosmia caused by a targeted disruption of the mouse olfactory cyclic nucleotide-gated cation channel
10. Information coding in the vertebrate olfactory system
11. The molecular architecture of odor and pheromone sensing in mamamals
12. A novel multigene family may encode odorant receptors: A molecular basis for odor recognition
13. T2Rs function as bitter taste receptors
14. 3-odors'
15. A novel family of divergent seven-transmembrane proteins: Candidate odorant receptors in Drosophila
16. Model systems for the study of seven transmembrane segment receptors
17. Evolution of odorant receptors
18. Odor processing in the frog olfactory system
19. Odor response properties of rat olfactory receptor neuron
20. Scentsational ion channels
21. Neuronal Ca2+-activated Cl-channels-homing in an elusive channel species
22. Identification of candidate Drosophila olfactory receptors from genomic DNA sequence
23. Truncation releases olfactory receptors from the endoplasmic reticulum of heterologous cells
24. The complete human olfactory subgenome
25. Mechanisms of olfactory discrimination: Converging evidence for common principles across phyla
26. Local distribution of odor responsivities of mouse olfactory receptor neurons
27. Molecular bases of odor discrimination: Reconstitution of olfactory receptors that recognize overlapping sets of odorants
28. Identification of ligands for olfactory receptors by functional expression of a receptor library
29. Ionic channels mediating sensory transduction
30. Mechanism of odorant adaptation in the olfactory receptor cell
31. 2+ dependent adaptive properties in the solitary olfactory receptor cell of the newt
32. Co-existence of cationic and chloride components in odorant-induced current of vertebrate olfactory receptor neurons
33. High activity of adenyl cyclase in olfactory and gustatory organs
34. Taste reception
35. Functional mosaic organization of mouse olfactory receptor neurons
36. Combinatorial receptor codes for odors
37. Seven transmembrane proteins as odorant and chemosensory receptors
38. Molecular biology of odorant receptor in vertebrate
39. Visualizing an olfactory sensory map
40. The olfactory bulb: Coding and processing of odor molecule information
41. Cellular and molecular constituents of olfactory sensation in vertebrates
42. A cyclic nucleotide-gated conductance in olfactory receptor cilia
43. Molecular biology of visual pigments
44. Spatial pattern of receptor expression in the olfactory epithelium
45. Odorant-sensitive adenylate cyclase may mediate olfactory reception
46. The variable and conserved interfaces of modeled olfactory receptor proteins
47. Multiple profile-multiple receptor site model for vertebrate olfaction
48. Expression of mRNAs encoding for two different olfactory receptors in a subset of olfactory receptor neurons
49. Signal pathways in odorant detection
50. A zonal organization of odorant receptor gene expression in the olfactory epithelium
51. Information coding in the olfactory system: Evidence for a stereotyped and highly organized epitope map in the olfacory bulb
52. Stimulation of olfactory receptors alters regulation of Ca2+ in olfactory neurons of the catfish
53. 2+ gradients in rat olfactory neurons
54. Second messenger signaling in olfactory transduction
55. Distribution of olfactory receptor genes in the human genome
56. Tuning specificities to aliphatic odorants in mouse olfactory receptor neurons and their local distribution
57. Transduction mechanisms in vertebrate olfactory receptor cells
58. Analysis of the molecular basis for octanal interactions in the expressed rat I7 olfactory receptor
59. Potential ligand-binding residues in rat olfactory receptor identified by correlated mutation analysis
60. The odorant-sensitive adenylate cyclase of olfactory receptor cells: Differential stimulation by distinct classes of odorants
61. Expression of odorant receptors in spatially restricted subsets of chemosensory neurons
62. Rostrocaudal patterning of receptor expressing neurons in the rat nasal cavity
63. Calcium signals in olfactory neurons
64. Functional cloning and reconstitution of vertebrate odorant receptors
65. Functional identification and reconstitution of an odorant receptor in single olfactory neurons
66. Chemosensory signaling in C. elegans
67. Divergent seven transmembrane receptors are candidate chemosensory receptors in C. elegans
68. Spatial segregation of odorant receptor expression in the mammalian olfactory epithelium
69. Topographic organization of sensory projections to the olfactory bulb
70. Cross-talk between olfactory second messenger pathways
71. A spatial map of olfactory receptor expression in the Drosophila antenna
72. Odorant receptors govern the formation of a precise topographic map
73. Phosphorylation and inhibition of olfactory adenylyl cylcase by CaM kinase II in neurons: A mechanism for attenuation of olfactory signals
74. Specificity and sensitivity of human olfactory receptor functionally expressed in human embryonic kidney 293 cells and Xenopus laevis oocytes
75. Disruption of the type III adenylyl cyclase gene leads to peripheral and behavioral anosmia in transgenic mice
76. Functional expression of a mammalian odorant receptor
77. The human olfactory receptor repertoire
78. Inhibition of the olfactory cyclic nucleotide gated ion channel by intracellular calcium