The 5′-leader of tobacco mosaic virus promotes translation through enhanced recruitment of elF4F

Nucleic Acids Research

Volumn 30, Issue 15, 2002, Pages 3401-3411

  Gallie, Daniel R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; CYTOSINE; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 101; INITIATION FACTOR; INITIATION FACTOR 3; INITIATION FACTOR 4F; INITIATION FACTOR 4G; MESSENGER RNA; POLYADENYLATED RNA; UNCLASSIFIED DRUG; CAPPED RNA; HSP101 PROTEIN, PLANT; TRANSCRIPTION FACTOR; VEGETABLE PROTEIN; VIRUS RNA;

3' UNTRANSLATED REGION; ARTICLE; BINDING SITE; CELL LYSATE; CONTROLLED STUDY; GENETIC ANALYSIS; HEAT SHOCK; NONHUMAN; PLANT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RNA TRANSLATION; TOBACCO MOSAIC VIRUS; TRANSLATION REGULATION; 5' UNTRANSLATED REGION; GENE EXPRESSION REGULATION; GENETICS; HEAT SHOCK RESPONSE; METABOLISM; POLYADENYLATION; PROTEIN SYNTHESIS; PROTEIN TRANSPORT;

EUKARYOTA; NICOTIANA TABACUM; TOBACCO MOSAIC VIRUS;

3' UNTRANSLATED REGIONS; 5' UNTRANSLATED REGIONS; EUKARYOTIC INITIATION FACTOR-4F; GENE EXPRESSION REGULATION, VIRAL; HEAT-SHOCK RESPONSE; PEPTIDE INITIATION FACTORS; PLANT PROTEINS; POLYADENYLATION; PROTEIN BIOSYNTHESIS; PROTEIN TRANSPORT; RNA CAPS; RNA, MESSENGER; RNA, VIRAL; TOBACCO MOSAIC VIRUS; TRANSCRIPTION FACTORS;

EID: 0036667328     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Physical and functional interactions between the mRNA cap structure and the poly(A) tail
2. Association of the yeast poly(A) tail binding protein with translation initiation factor elF-4G
3. Translation initiation factors elF-iso4G and elF-4B interact with the poly(A)-binding protein and increase its RNA binding activity
4. Wheat germ poly(A) binding protein enhances the binding affinity of eukaryotic initiation factor 4F and (iso)4F for cap analogues
5. The phosphorylation state of poly(A)-binding protein specifies its binding to poly(A) RNA and its interaction with eukaryotic initiation factor (eIF) 4F, eIFiso4F and eIF4B
6. Disruption of the interaction of mammalian protein synthesis eukaryotic initiation factor 4B with the poly(A)-binding protein by caspase- and viral protease-mediated cleavages
7. Contranslational disassembly to tobacco mosaic virus in vitro
8. Contranslational disassembly increases the efficiency of expression of TMV RNA in wheat germ cell-free extracts
9. Evidence that tobacco mosaic virus particles disassemble contranslationally in vivo
10. Complete uncoating of the 5′ leader sequence of tobacco mosaic virus RNA occurs rapidly and is required to initiate cotranslational virus disassembly in vitro
11. Uncoating of tobacco mosaic virus RNA in protoplasts
12. RNA pseudoknot domain of tobacco mosaic virus can functionally substitute for a poly(A) tail in plant and animal cells
13. A phylogenetically conserved sequence within viral 3′ untranslated RNA pseudoknots regulates translation
14. The 5′-leader sequence of tobacco mosaic virus RNA enhances the expression of foreign gene transcripts in vitro and in vivo
15. Mutational analysis of the tobacco mosaic virus 5′-leader for altered ability to enhance translation
16. Identification of the motifs within the tobacco mosaic virus 5′ leader responsible for enhancing translation
17. In vivo uncoating and efficient transient expression of recombinant RNA packaged into pseudovirus particles
18. HSP101 functions as a specific translational regulatory protein whose activity is regulated by nutrient status
19. Synthesis of long, capped transcripts in vitro by SP6 and T7 RNA polymerases
20. Identification of an isozyme form of protein synthesis initiation factor 4F in plants
21. Identification of a new protein synthesis initiation factor from wheat germ
22. Purification and properties of protein synthesis initiation and elongation factors from wheat germ
23. Expression in Escherichia coli of the two subunits of the isozyme form of wheat germ protein synthesis initiation factor 4F. Purification of the subunits and formation of an enzymatically active complex
24. eIF4G functionally differs from eIFiso4G in promoting internal initiation, cap-independent translation and translation of structured mRNAs
25. Cap-independent translation conferred by the 5′-leader of tobacco etch virus is eIF4G-dependent
26. The cap and poly(A) tail function synergistically to regulate mRNA translational efficiency
27. Kinetics of induced enzyme synthesis determination of the mean life of galactosidase-specific messenger RNA
28. Functional mRNA half lives in E. coli
29. Quantitation of parameters that determine the rate of ovalbumin synthesis
30. Heat shock disrupts cap and poly(A) tail function during translation and increase mRNA stability of introduced reporter mRNA
31. Heat shock protein HSP101 binds to the Fed-1 internal light regulator y element and mediates its high translational activity
32. Developmental and thermal regulation of the maize heat shock protein, Hsp101
33. The tobacco etch viral 5′ leader and poly(A) tail are synergistic regulators of translation
34. Identification and characterization of the functional elements within the tobacco etch viral 5′-leader required for cap-independent translation
35. Determination of the amounts of the protein synthesis initiation and elongation factors in wheat germ