Diazine-derived guanidines, isothioureas, and isoureas: Synthesis and attempts of configurational assignment

Journal of Heterocyclic Chemistry

Volumn 39, Issue 4, 2002, Pages 695-702

  Heinisch, Gottfried ^a   Matuszczak, Barbara ^a   Rakowitz, Dietmar ^a   Mereiter, Kurt ^b  

^a UNIVERSITY OF INNSBRUCK   (Austria)

^b VIENNA UNIVERSITY OF TECHNOLOGY   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

1,1 DIMETHYLETHYLPYRIDAZIN 3 YL CARBODIIMIDE; 1,1 DIMETHYLETHYLPYRIMIDIN 2 YL CARBODIIMIDE; CYANAMIDE; GUANIDINE DERIVATIVE; SULFADIAZINE; THIOUREA DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; NUCLEAR OVERHAUSER EFFECT; REACTION ANALYSIS; SYNTHESIS; X RAY ANALYSIS;

EID: 0036666308     PISSN: 0022152X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jhet.5570390414     Document Type: Article

References (23)

1. G. Heinisch, B. Matuszczak, G. Pürstinger, and D. Rakowitz; J. Heterocyclic Chem. 32, 13 (1995).
2. For a review see W. Raßhofer, "Monokohlensäurederivate: Monokohlensäure-Derivate mit zwei kumulierten C,XDoppelbindungen: Carbodiimide" in Houben-Weyl, "Methoden der organischen Chemie", Bd. E4, 883-914, Thieme Verlag, Stuttgart (1983).
3. F. Kurzer and K. Douraghi-Zadeh, Chem. Rev., 67, 107 (1967).
4. J. A. Oates, "Antihypertensive Agents and the Drug Therapy of Hypertension" in J. G. Hardman, L. E. Limbird, and A. Goodman Gilman (eds), "Goodman & Gilman's The Pharmacological Basis of Therapeutics", 781-808, McGraw-Hill (1995).
5. B. B. Hoffman and R. J. Lefkowitz, "Catecholamines, Sympathomimetic Drugs, and Adrenergic Receptor Antagonists" in J. G. Hardman, L. E. Limbird, and A. Goodman Gilman (eds), Goodman & Gilman's The Pharmacological Basis of Therapeutics, 199-248, McGraw-Hill (1995).
6. H. J. Petersen, C. K. Nielsen, and E. Arrigoni-Martelli, J. Med. Chem., 21, 773 (1978); P. W. Manley and U. Quast, J. Med. Chem., 35, 2327 (1992).
7. H. J. Petersen, C. K. Nielsen, and E. Arrigoni-Martelli, J. Med. Chem., 21, 773 (1978); P. W. Manley and U. Quast, J. Med. Chem., 35, 2327 (1992).
8. L. L. Brunton, "Agents for Control of Gastric Acidity and Treatment of Peptic Ulcers" in J. G. Hardman, L. E. Limbird, and A. Goodman Gilman (eds), "Goodman & Gilman's The Pharmacological Basis of Therapeutics", 901-916, McGraw-Hill (1995).
9. K. Amagase, S. Kato, H. Yamamoto, and S. Okabe, Arzneim.-Forsch./Drug Res., 46, 177 (1996); Drugs Fut., 18, 809 (1993).
10. K. Amagase, S. Kato, H. Yamamoto, and S. Okabe, Arzneim.-Forsch./Drug Res., 46, 177 (1996); Drugs Fut., 18, 809 (1993).
11. [a] W. Howson, M. E. Parsons, P. Raval, and G. T. G. Swayne, Bioorg. Med. Chem. Lett., 2, 77 (1992);
12. [b] H. van der Goot, M. J. P. Schepers, G. J. Sterk, and H. Timmerman, Eur. J. Med. Chem., 27, 511 (1992).
13. B. G. Shearer, S. Lee, J. A. Oplinger, L. W. Frick, E. P. Garvey, and E. S. Furfine, J. Med. Chem., 40, 1901 (1997).
14. [a] Drugs Fut., 6, 369 (1981);
15. [b] Drugs Fut., 12, 612 (1987);
16. [c] Drugs Fut., 13, 592 (1988).
17. Drugs Fut., 22, 1197 (1997).
18. T. Iwamoto, T. Watano, and M. Shigekawa, J. Biol. Chem., 37, 22391 (1996).
19. N. L. Reddy, L.-Y. Hu, R. E. Cotter, J. B. Fischer, W. J. Wong, R. N. McBurney, E. Weber, D. L. Holmes, S. T. Wong, R. Prasad, and J. F. W. Keana, J. Med. Chem., 37, 260 (1994).
20. [a] G. Heinisch and W. Holzer, Monatsh. Chem., 121, 837 (1990);
21. [b] G. Heinisch and W. Holzer, Collect. Czech. Chem. Commun., 56, 2251 (1991);
22. [c] J. Easmon, G. Heinisch, and W. Holzer, Sci. Pharm., 61, 3 (1993).
23. G. M. Sheldrick, SHELX97. Program system for crystal structure determination. University of Göttingen, Germany, 1997.