Characterization and application of a vinblastine-selected Caco-2 cell line for evaluation of P-glycoprotein

In Vitro Cellular and Developmental Biology - Animal

Volumn 38, Issue 7, 2002, Pages 401-410

  Laska, Dennis A ^a   Houchins, Jack O ^a   Pratt, Susan E ^a   Horn, Jeffery ^a   Xia, Xialong ^a   Hanssen, Brenda R ^a   Williams, Daniel C ^a   Dantzig, Anne H ^a   Lindstrom, Terry ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

ABC transporters; ADME; Caco 2; Caco 2 VinB; Calcein AM; P glycoprotein (Pgp)

Indexed keywords

AMIODARONE; AMITRIPTYLINE; CALCEIN; CAPTOPRIL; CIMETIDINE; CLOTRIMAZOLE; CYCLOSPORIN; DEXAMETHASONE; DIGOXIN; ERYTHROMYCIN; ESTRADIOL; ETOPOSIDE; GLYCOPROTEIN P; KETOCONAZOLE; KETOPROFEN; METHOTREXATE; METOPROLOL; NADOLOL; NIFEDIPINE; ORPHENADRINE; PRAZOSIN; PROPANOL; QUINIDINE; RESERPINE; RIFAMPICIN; SALAZOSULFAPYRIDINE; THIORIDAZINE; UNINDEXED DRUG; VERAPAMIL; VINBLASTINE;

ARTICLE; ASSAY; CELL DIFFERENTIATION; CELL POPULATION; CELL STRAIN; CELL STRAIN CACO 2; CELL STRUCTURE; CELL SURVIVAL; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; DRUG POTENCY; DRUG TRANSPORT; EVALUATION; FLUORESCENCE; HUMAN; HUMAN CELL; INTESTINE; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; SCANNING ELECTRON MICROSCOPY; TRANSMISSION ELECTRON MICROSCOPY; TREATMENT INDICATION; UPREGULATION; WESTERN BLOTTING; XENOBIOTIC METABOLISM;

ANTINEOPLASTIC AGENTS; BIOLOGICAL TRANSPORT; BLOTTING, WESTERN; CACO-2 CELLS; CELL MEMBRANE; CELL SURVIVAL; DIGOXIN; DRUG RESISTANCE, NEOPLASM; FLUORESCEINS; FLUORESCENCE; HUMANS; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON; P-GLYCOPROTEIN; VINBLASTINE;

EID: 0036665676     PISSN: 10712690     EISSN: None     Source Type: Journal    
DOI: 10.1290/1071-2690(2002)038<0401:CAAOAV>2.0.CO;2     Document Type: Article

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