Molecular basis of sweet taste in dipeptide taste ligands

Pure and Applied Chemistry

Volumn 74, Issue 7, 2002, Pages 1109-1116

  Goodman, M ^a   Del Valle, J R ^a   Amino, Y ^b   Benedetti, E ^c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b AJINOMOTO CO INC   (Japan)

^c UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC COMPOUND; ASPARTAME; DIPEPTIDE; GUAIACOL; LIGAND; N 3,3 DIMETHYLBUTYL DERIVATIVE; NEOTAME; SWEETENING AGENT; UNCLASSIFIED DRUG;

CHEMICAL STRUCTURE; CONFERENCE PAPER; CONFORMATION; CRYSTAL STRUCTURE; HYDROPHOBICITY; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; SWEETNESS; X RAY DIFFRACTION;

EID: 0036664970     PISSN: 00334545     EISSN: None     Source Type: Journal    
DOI: 10.1351/pac200274071109     Document Type: Conference Paper

References (9)

1. D. E. Walters, I. Prakash, N. Desai. J. Med. Chem. 43, 1242-1245 (2000).
2. T. Yamazaki, E. Benedetti, D. Kent, M. Goodman. Angew. Chem., Int. Ed. Engl. 33, 1437-1451 (1994).
3. M. Goodman, Q. Zhu, D. Kent, Y. Amino, R. Iacovino, E. Benedetti, A. Santini. J. Pept. Sci. 3, 231-241 (1997).
4. R.-H. Mattern, Y. Amino, E. Benedetti, M. Goodman. J. Pept. Res. 50, 286-299 (1997).
5. M. Goodman, R.-H. Mattern, P. Gantzel, A. Santini, R. Iacovino, M. Saviano, E. Benedetti. J. Pept. Sci. 4, 229-238 (1998).
6. J. M. Tinti and C. Nofre. In Sweeteners: Discovery, Molecular Design, and Chemoreception, D. E. Walters, F. T. Orthoefer, G. E. Dubois (Eds.), American Chemical Society, Washington, DC (1990).
7. R.-H. Mattern, Y. Amino, E. Benedetti, M. Goodman. Biopolymers 49, 523-539 (1998).
8. Details of the design, synthesis, and conformational analysis of these compounds will be reported in a separate paper.
9. Data for the X-ray diffraction analyses will be published in due course.