Glycoprotein V: The predominant target antigen in gold-induced autoimmune thrombocytopenia

Blood

Volumn 100, Issue 1, 2002, Pages 344-346

  Garner, Stephen F ^a,b,c,d,e   Campbell, Kate ^a,b,c,d,e   Metcalfe, Paul ^a,b,c,d,e   Keidan, Jane ^a,b,c,d,e   Huiskes, Elly ^a,b,c,d,e   Dong, Jing Fei ^a,b,c,d,e   López, José A ^a,b,c,d,e   Ouwehand, Willem H ^a,b,c,d,e  

^a NHS BLOOD AND TRANSPLANT   (United Kingdom)

^b NATIONAL INSTITUTE FOR BIOLOGICAL STANDARDS AND CONTROL   (United Kingdom)

^c Queen Elizabeth Hospital King's Lynn NHS Trust   (United Kingdom)

^d CENTRAL LABORATORY   (Netherlands)

^e BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; AUTOANTIBODY; FIBRINOGEN RECEPTOR; GLYCOPROTEIN; GLYCOPROTEIN V; GOLD; UNCLASSIFIED DRUG;

ARTICLE; AUTOIMMUNE DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; GOLD THERAPY; HUMAN; PRIORITY JOURNAL; PROTEIN TARGETING; RHEUMATOID ARTHRITIS; THROMBOCYTE; THROMBOCYTOPENIA;

EID: 0036659933     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.V100.1.344     Document Type: Article

References (24)

1. Adachi JD, Bensen WG, Kassam Y, et al. Gold induced thrombocytopenia: 12 cases and a review of the literature. Semin Arthritis Rheum. 1987;16:287-293.
2. von dem Borne AEGK, Ouwehand WH. Immunology of platelet disorders. In: Caen JP, ed. Platelet Disorders. London, United Kingdom: Bailliere Tindall; 1989:749-782
3. Kiefel V, Santoso S, Kaufmann E, Mueller-Eckhardt C. Autoantibodies against platelet glycoprotein Ib/IX: a frequent finding in autoimmune thrombocytopenic purpura. Br J Haematol. 1991; 79:256-262.
4. Hou M, Stockelberg D, Kutti J, Wadenvik H. Antibodies against platelet GPIb/IX, GPIIb/IIIa, and other platelet antigens in chronic idiopathic thrombocytopenic purpura. Eur J Haematol. 1995;55:307-314.
5. Deckmyn H, Zhang J, Van Houtte E, Vermylen J. Production and nucleotide sequence of an inhibitory human IgM autoantibody directed against platelet glycoprotein Ia/IIa. Blood. 1994;84:1968-1974.
6. Godeau B, Piette JC, Fromont P, Intrator L, Schaeffer A, Bierling P. Specific antiplatelet glycoprotein autoantibodies are associated with the thrombocytopenia of primary antiphospholipid syndrome. Br J Haematol. 1997;98:873-879.
7. Proulle V, Masnou P, Cartron J, et al. GPIaIIa as a candidate target for anti-platelet autoantibody occurring during valproate therapy and associated with preoperative bleeding. Thromb Haemost. 2000;83:175-176.
8. Joutsi L, Kekomaki R. Comparison of the direct platelet immunofluorescence test (direct PIFT) with a modified direct monoclonal antibody-specific immobilization of platelet antigens (direct MAIPA) in detection of platelet-associated IgG. BrJ Haematol. 1997;96:204-209.
9. Joutsi-Korhonen L, Javela K, Hormila P, Kekomaki R. Glycoprotein V-specific platelet-associated antibodies in thrombocytopenic patients. Clin Lab Haematol. 2001;23:307-312.
10. Lopez JA, Dong JF. Structure and function of the glycoprotein Ib-IX-V complex. Curr Opin Hematol. 1997;4:323-329.
11. Mayer JL, Beardsley DS. Varicella-associated thrombocytopenia: autoantibodies against platelet surface glycoprotein V. Pediatr Res. 1996;40:615-619.
12. Meenaghan M, Judson PA, Yousaf K, Lewis L, Pamphilon DH. Antibodies to platelet glycoprotein V in polytransfused patients with haematological disease. Vox Sang. 1993;64:167-170.
13. Kiefel V, Santoso S, Weisheit M, Mueller Eckhardt C. Monoclonal antibody-specific immobilization of platelet antigens (MAIPA): a new tool for the identification of platelet-reactive antibodies. Blood. 1987;70:1722-1726.
14. Kiefel V. The MAIPA assay and its applications in immunohaematology. Transfus Med, 1992;2:181-188.
15. Berry JE, Murphy CM, Smith GA, et al. Detection of Gov system antibodies by MAIPA reveals an immunogenicity similar to the HPA-5 alloantigens. Br J Haematol. 2000;110:735-742.
16. von dem Borne AE, Helmerhorst FM, van Leeuwen EF, Pegels HG, von Riesz E, Engelfriet CP. Autoimmune thrombocytopenia: detection of platelet autoantibodies with the suspension immunofluorescence test. Br J Haematol. 1980;45:319-327.
17. Helmerhorst FM, van Oss CJ, Bruynes EC, Engelfriet CP, von dem Borne AE. Elution of granulocyte and platelet antibodies. Vox Sang. 1982;43:196-204.
18. von dem Borne AE, Vos JJ, van der Lelie J, Bossers B, van Dalen CM. Clinical significance of positive platelet immunofluorescence test in thrombocytopenia. Br J Haematol. 1986;64:767-776.
19. Lewis D, Capell HA, McNeil CJ, Iqbal MS, Brown DH, Smith WE. Gold levels produced by treatment with auranofin and sodium aurothiomalate. Ann Rheum Dis. 1983;42:566-570.
20. Dong JF, Sae-Tung G, Lopez JA. Role of glycoprotein V in the formation of the platelet high-affinity thrombin-binding site. Blood. 1997;89:4355-4363.
21. Li CQ, Dong JF, Lanza F, Sanan DA, Sae Tung G, Lopez JA. Expression of platelet glycoprotein (GP) V in heterologous cells and evidence for its association with GP lb alpha in forming a GP Ib-IX-V complex on the cell surface. J Biol Chem. 1995;270:16302-16307.
22. th ed. Oxford, United Kingdom: Blackwell Science; 1997.
23. von dem Borne AE, Pegels JG, van der Stadt RJ, van der Plas-van Dalen CM, Helmerhorst FM. Thrombocytopenia associated with gold therapy: a drug-induced autoimmune disease? Br J Haematol. 1986;63:509-516.
24. Moog S, Mangin P, Lenain N, et al. Platelet glycoprotein V binds to collagen and participates in platelet adhesion and aggregation. Blood. 2001;98:1038-1046.