High salt intake inhibits nitric oxide synthase expression and aggravates hypertension in rats with chronic renal failure

Journal of Nephrology

Volumn 15, Issue 4, 2002, Pages 407-413

  Campese, Vito M ^a   Mozayeni, Pantea ^a   Ye, Shaohua ^a   Gumbard, Michael ^a  

^a LAC USC MEDICAL CENTER   (United States)

Author keywords

Chronic renal failure; Hypertension; Nitric oxide; Norepinephrine; Sympathetic nerve activity

Indexed keywords

MESSENGER RNA; NITRIC OXIDE SYNTHASE; NORADRENALIN;

ADRENERGIC SYSTEM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTERIOR HYPOTHALAMUS; BLOOD PRESSURE MEASUREMENT; BRAIN TISSUE; CHRONIC KIDNEY FAILURE; CONCENTRATION (PARAMETERS); CONFERENCE PAPER; CONTROLLED STUDY; DISEASE EXACERBATION; EVIDENCE BASED MEDICINE; GENE EXPRESSION; HYPERTENSION; LOCUS CERULEUS; MALE; MESENTERIC ARTERY; MESENTERY BLOOD VESSEL; NEPHRECTOMY; NONHUMAN; NORADRENALIN BRAIN LEVEL; NUCLEOTIDE SEQUENCE; PATHOPHYSIOLOGY; POSTERIOR HYPOTHALAMUS; RAT; SODIUM INTAKE; SODIUM RETENTION;

ANALYSIS OF VARIANCE; ANIMALS; BASE SEQUENCE; BLOOD PRESSURE DETERMINATION; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HEMODYNAMIC PROCESSES; HYPERTENSION, RENAL; KIDNEY FAILURE, CHRONIC; MALE; MOLECULAR SEQUENCE DATA; NEPHRECTOMY; NITRIC OXIDE SYNTHASE; NOREPINEPHRINE; RATS; RATS, SPRAGUE-DAWLEY; REFERENCE VALUES; REGRESSION ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RISK ASSESSMENT; RNA, MESSENGER; SENSITIVITY AND SPECIFICITY; SODIUM CHLORIDE, DIETARY;

EID: 0036659005     PISSN: 11218428     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (38)

1. Coleman TG, Guyton AC. Hypertension caused by salt loading in the dog: III. Onset transients of cardiac output and other variables. Circ Res 1969; 25: 153-60.
2. Weidman P. Pathogenesis of hypertension associated with chronic renal failure. Contrib Nephrol 1984; 41: 47-65.
3. De Wardener HE, Mac Gregor GA. Dahl's hypothesis that a saluretic substance may be responsible for a sustained rise in arterial pressure: it's possible role in essential hypertension. Kidney Int 1980; 18: 1-9.
4. Graves SW, Glatter KA, Lazarus JM, Williams GH, Hollenberg NK. Volume expansion in renal failure patients: a paradigm for a clinically relevant [Na,K]ATPase inhibitor. J Cardiovasc Pharmacol 1993; 22 (suppl 2): S54-7.
5. Tobian L Jr., Binion JT. Tissue cations and water in arterial hypertension. Circulation 1952; 5: 754-8.
6. Atuk NO, Bailey CJ, Turner S, Peach MJ, Westervelt FB Jr. Red blood cell catechol-o-methyl transferase, plasma catecholamines and renin in renal failure. Trans Am Soc Artif Intern Organs 1976; 22: 195-200.
7. Lake CR, Ziegler MG, Coleman MD, Kopin IJ. Plasma levels of norepinephrine and dopamine-beta-hydroxylase in CRF patients treated with dialysis. Cardiovasc Med 1979; 1: 1099-111.
8. Henrich WL, Katz FH, Molinoff PB, Schrier RW. Competitive effects of hypokalemia and volume depletion on plasma renin activity, aldosterone and catecholamine concentrations in hemodialysis patients. Kidney Int 1977; 12: 279-84.
9. Izzo JL, Izzo MS, Sterns RH, Freeman RB. Sympathetic nervous system hyperactivity in maintenance hemodialysis patients. Trans Am Soc Artif Intern Organs 1982; 28: 604-7.
10. Cuche JL, Prinseau J, Selz F, Ruget G, Baglin A. Plasma free, sulfo- and glucuro-conjugated catecholamines in uremic patients. Kidney Int 1986; 30: 566-72.
11. Bigazzi R, Kogosov E, Campese VM. Altered norepinephrine turnover in the brain of rats with chronic renal failure. J Am Soc Nephrol 1994; 4: 1901-7.
12. Campese VM, Kogosov E. Renal afferent denervation prevents hypertension in rats with chronic renal failure. Hypertension 1995; 25: 878-82.
13. Ye S, Ozgur B, Campese VM. Renal afferent impulses, the posterior hypothalamus, and hypertension in rats with chronic renal failure. Kidney Int 1997; 51: 722-7.
14. Converse RL Jr, Jacobsen TN, Toto RD, Jost CM, Cosentino F, Fouad-Tarazi F, Victor RG. Sympathetic overactivity in patients with CRF. N Engl J Med 1992; 327: 1912-8.
15. Campese VM, Romoff MS, Levitan D, Saglikes R, Friedler R, Massry SG. Abnormal relationship between sodium intake and sympathetic nervous system activity in salt-sensitive patients with essential hypertension. Kidney Int 1982; 21: 371-8.
16. Bredt DS, Hwang PM, Snyder SH. Localization of nitric oxide synthase indicating a neuronal role for nitric oxide. Nature 1990; 347: 768-70.
17. Vincent S.R., Kimura H. Histochemical mapping of nitric oxide synthase in the rat brain. Neuroscience 1992; 6: 755-84.
18. Tseng CJ, Liu HY, Lin HC, Ger LP, Tung CS, Yen MH. Cardiovascular effects of nitric oxide in the brain stem nuclei of rats. Hypertension 1996; 27: 36-42.
19. G-methyl-L-arginine, an inhibitor of L-arginine-derived nitric oxide synthesis, stimulates renal sympathetic nerve activity. Circ Res 1992; 70: 607-11.
20. Sander M, Hansen PG, Victor RG. Sympathetically mediated hypertension caused by chronic inhibition of nitric oxide. Hypertension 1995; 26: 691-5.
21. Matsuoka H, Nishida H, Nomura G, van Vliet BN, Toshima H. Hypertension induced by nitric oxide synthesis inhibition is renal nerve dependent. Hypertension 1994; 23: 971-5.
22. Ye S, Nosrati S, Campese VM. Nitric oxide (NO) modulates the neurogenic control of blood pressure in rats with chronic renal failure. J Clin Invest 1997; 99: 540-8.
23. 3H] dopa in various regions of the brain. J Neurochem 1966; 13: 665-9.
24. Palkovits M, Zaborszky L. Neuroanatomy of central cardiovascular control. In W. de Jong, A.P. Provoost and A.P. Shapiro Eds, Hypertension and Brain Mechanisms, Progress in Brain Research, Vol 47, Elsevier, Amsterdam, 1977; 9-34.
25. Nakata T, Berard W, Kogosov E, Alexander N. Microdialysis in the posterior hypothalamus: Sodium chloride affects norepinephrine release, mean arterial pressure, heart rate and behavious in awake rats. Brain Res Bull 1990; 25: 593-8.
26. Higuchi R, Dollinger G. Simultaneous amplification and detection of specific DNA sequences. Biotechnology 1992; 10: 413-7.
27. Enoch DM, Kerr FW. Hypothalamic vasopressor and vesicopressor pathways. Arch Neurol 1967; 16: 290-306.
28. Takeda K, Bunag RD. Sympathetic hyperactivity during hypothalamic stimulation in spontaneously hypertensive rats. J Clin Invest 1978; 62: 642-8.
29. Juskevich JC, Robinson DS, Whitehorn D. Effect of hypothalamic stimulation in spontaneously hypertensive and Wistar-Kyoto Rats. Eur J Pharmacol 1978; 51: 429-39.
30. Bunag RD, Eferakey AE, Immediate hypotensive after-effects of posterior hypothalamic lesions in awake rats with spontaneous, renal, or DOCA hypertension. Cardiovasc Res 1976; 10: 663-71.
31. Patel KP, Line RL. Influence of renal nerves on noradrenergic responses to changes in arterial pressure. Am J Physiol 1984; 247: R615-20.
32. Chalmers JP. Brain amines and models of experimental hypertension. Circ Res 1975; 36: 469-80.
33. Swanson LW, Hartmann BK. The central adrenergic system: an immunofluorescence study of the location of cell bodies and their efferent connection in the rat utilizing dopamine-β-hydroxylase as a marker. J Comp Neurol 1975; 163: 467-505.
34. Bunag RD, Inoue A. Differentiated pressor and sympathetic responses to dual brain stimulation: Ventromedial hypothalamus versus locus coeruleus. Proc Soc Exp Biol Med 1985; 178: 91-100.
35. Ward DG, Gunn CG. Locus coeruleus complex: elicitation of a pressor response and a brain stem region necessary for its occurrence. Brain Res 1976; 107: 401-11.
36. Kawasaki S, Takeda K, Tanaka M, Itoh H, Hirata M, Nakata T, Hayashi J, Oguro M, Sasaki S, Nakagawa M. Enhanced norepinephrine release in hypothalamus from locus coeruleus in SHR. Jpn Heart J 1991; 32: 255-62.
37. Kawamura H, Gunn CG, Frohlich ED. Cardiovascular alteration by nucleus locus coeruleus in spontaneously hypertensive rat. Brain Res 1978; 140: 137-47.
38. Przuntek H, Philippu A. Reduced pressor responses to stimulation of the locus coeruleus after lesion of the posterior hypothalamus. Naunyn-Schmiedebergs Arch Pharmacol 1973; 276; 119-22.