Atypical β-adrenoceptor relaxation but not β3 is imparied in spontaneously hypertensive rats;Altération de la relaxation β-adrénergique atypique non β3 dans l'hypertension artérielle chez le rat

Archives des Maladies du Coeur et des Vaisseaux

Volumn 95, Issue 7-8, 2002, Pages 647-650

  Mallem, Y ^a   Serpillon, S ^a,b   Gautier, F ^a   Gogny, M ^a   Gauthier, C ^b   Desfontis, J Cl ^a,b  

^a ENV   (France)

^b INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

4 (3 TERT BUTYLAMINO 2 HYDROXYPROPOXY) 2 BENZIMIDAZOLONE; 9 (TETRAHYDRO 2 FURYL)ADENINE; [[7 [[2 (3 CHLOROPHENYL) 2 HYDROXYETHYL]AMINO] 5,6,7,8 TETRAHYDRO 2 NAPHTHYL]OXY]ACETIC ACID ETHYL ESTER; BETA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; BETA 3 ADRENERGIC RECEPTOR STIMULATING AGENT; BETA ADRENERGIC RECEPTOR; CYCLIC AMP; L 748337; N (2 PHENYLCYCLOPENTYL)AZACYCLOTRIDECAN 2 IMINE; NADOLOL; PHENYLEPHRINE; UNCLASSIFIED DRUG;

ANALYSIS OF VARIANCE; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ESSENTIAL HYPERTENSION; INHIBITION KINETICS; NONHUMAN; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; STRAIN DIFFERENCE; VASCULAR RING;

ANIMALS; CULTURE TECHNIQUES; ENDOTHELIUM, VASCULAR; HYPERTENSION; RATS; RATS, INBRED SHR; RECEPTORS, ADRENERGIC, BETA; RECEPTORS, ADRENERGIC, BETA-3;

EID: 0036657470     PISSN: 00039683     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Feldman RD, Gros R. Impaired vasodilator function in hypertension. The role of alterations in receptor-G protein coupling. Trends Cardiovasc Med 1998; 8: 297-305.
2. Fujimoto S, Dohi Y, Aoki K, Matsuda T. Beta 1- and beta 2- adrenoceptor-mediated relaxation responses in peripheral arteries from spontaneously hypertensive rats at pre- hypertensive and early hypertensive stages. J Hypertens 1988; 6: 543-50.
3. Trochu JN, Leblais V, Rautureau Y et al. Beta 3-adrenoceptor stimulation induces vasorelaxation mediated essentially by endothelium-derived nitric oxide in rat thoracic aorta. Br J Pharmacol 1999; 128: 69-76.
4. Donckier JE, Massart PE, Van Mechelen H, Heyndrickx GR, Gauthier C, Balligand JL. Cardiovascular effects of beta 3-adrenoceptor stimulation in perinephritic hypertension. Eur J Clin Invest 2001; 31: 681-9.
5. 3-adrenoceptors mediating relaxation of aesophageal smooth muscle of spontaneously hypertensive rats. Br J Pharmacol 1996; 119: 1355-60.
6. Iwase M, Ishikawa K, Tashiro K et al. Effects of monosodium glutamate-induced obesity in spontaneously hypertensive rats vs Wistar-Kyoto rats: serum leptin and blood flow to brown adipose tissue. Hypertens Res 2000; 23: 503-10.
7. Oriowo MA. Atypical beta-adrenoceptor in the rat isolated common carotid artery. Br J Pharmacol 1994; 113: 699-702.
8. Brawley L, Shaw AM, MacDonald A. Role of endothelium/nitric oxide in atypical β-adrenoceptor-mediated relaxation in rat isolated aorta. Eur J Pharmacol 2000; 398: 285-96.
9. 1-adrenergic receptor. Am J Physiol 2001; 43: E199-E202.
10. 4-adrenoceptor pharmacology. Naunyn-Schmiedeberg's Arch Pharmacol 2001; 363: 87-93.
11. Anand-Srivastava MB. G-proteins and adenylyl cyclase signalling in hypertension. Mol Cell Biochem 1996; 157: 163-70.