The effect of surfactant-based elastic and rigid vesicles on the penetration of lidocaine across human skin

S.T.P. Pharma Sciences

Volumn 12, Issue 4, 2002, Pages 257-262

  Honeywell Nguyen, P L ^a   Van den Bussche, M H ^a   Junginger, H E ^a   Bouwstra, J A ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Elastic vesicles; Human skin; Lidocaine

Indexed keywords

L 595; LIDOCAINE; OCTAOXYETHYLENE LAURATE ESTER; SUCROSE LAURATE ESTER; SURFACTANT; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DERMATOME; DRUG FORMULATION; DRUG PENETRATION; DRUG TRANSPORT; ELASTICITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; IN VITRO STUDY; LIPID VESICLE; MICELLE; PH; SKIN PENETRATION;

EID: 0036656852     PISSN: 11571489     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Yu H., Liao H. - Triamcinolone permeation from different liposome formulations through rat skin in vitro. - Int. J. Pharm., 127, 1-7, 1996.
2. Fresta M., Puglisi G. - Corticosteroid dermal delivery with skin-lipid liposomes. - J. Control. Rel., 44, 141-151, 1997.
3. Du Plessis J., Weiner N., Muller D.G. - The influence of in vivotreatment of skin with liposomes on the topical absorption of a hydrophilic and a hydrophobic drug in vitro. - Int. J. Pharm, 103, R1-R5, 1994.
4. Cevc G., Schatzlein A., Gebauer D., Blume G. - Ultra-high efficiency of drug and peptide transfer through the intact skin by means of novel drug-carriers, Transfersomes. - In: Prediction of Percutaneous Penetration, Volume 3B, K.R. Brain, V.J. James, K.A. Walters Eds., STS Publishing, UK, 1993, pp. 226-236.
5. Cevc G., Gebauer D., Stieber J., Schatzlein A., Blume G. - Ultraflexible vesicles, Transfersomes, have an extremely low pore penetration resistance and transport therapeutic amounts of insulin across the intact mammalian skin. - Biochim. Biophys. Acta, 1368, 201-215, 1998.
6. Planas M.E., Gonzalez P., Rodriguez L., Sanchez S., Cevc G. - Non-invasive percutaneous induction of topical analgesia by a new type of drug carrier, and prolongation of local pain insensitivity by anesthetic liposomes. - Anesth. Analg., 75, 615-21, 1992.
7. Van Den Bergh B.A.I. - Elastic liquid state vesicles as a tool for topical drug delivery. - Thesis, Leiden University, The Netherlands, 1999, pp. 49-63.
8. Van Den Bergh B.A.I., Wertz P.W., Junginger H.E., Bouwstra J.A. - Elasticity of vesicles assessed by electron spin resonance, electron microscopy and extrusion measurements. - Int. J. Pharm., 217, 13-24, 2001.
9. Van Den Bergh B.A.I., Vroom J., Gerritsen H., Junginger H.E., Bouwstra J.A. - Interactions of elastic and rigid vesicles with human skin in vitro: electron microscopy and two-photon excitation microscopy. - Biochim. Biophys. Acta, 1461, 155-173, 1999.
10. Honeywell-Nguyen P.L., De Graaff A., Junginger H.E., Bouwstra J.A. - Interaction between elastic and rigid vesicles with human skin in vivo. - Proc. Int. Symp. Control. Rel. Bioact. Mater., 27, 237-238, 2000.
11. Van Den Bergh B.A.I., Bouwstra J.A., Junginger H.E., Wertz P.W.- Elasticity of vesicles affects hairless mouse skin structure and permeability. - J. Control. Rel., 62, 367-379, 1999.
12. Baillie A.J., Florence A.T., Hume L.R., Muirhead G.T., Rogerson A. - The preparation and properties of niosomes - non-ionic surfactant vesicles. - J. Pharm. Pharmacol., 37,863-868, 1985.
13. El Maghraby G.M.M., Williams A.C., Barry B.W. -Oestradiol skin delivery from ultradeformable liposomes: refinement of surfactant concentration. - Int. J. Pharm., 196, 63-74, 2000.
14. Paul A., Cecv G., Bachhawat B.K. - Transdermal immunisation with an integral membrane component, gap junction protein, by means of ultradeformable drug carriers, transfersomes. - Vaccine, 16 (2/3), 188-195, 1998.
15. El Maghraby G.M.M., Williams A.C., Barry B.W. - Skin delivery of oestradiol from deformable and traditional liposomes: Mechanistic studies. - J. Pharm. Pharmacol., 51, 1123-1134, 1999.