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Volumn 73, Issue 7, 2002, Pages 716-720

Reduction of the angiogenesis score and tumor growth in subcutaneously implanted colon carcinoma in a mouse model;Leflunomid reduziert den Angiogenese-score und das Tumorwachstum subkutan implantierter Kolonkarzinomzellen im Mausmodell

Author keywords

Angiogenesis inhibition; Leflunomide; Tyrosine kinase receptor

Indexed keywords

ISOXAZOLE DERIVATIVE; LEFLUNOMIDE; URIDINE;

EID: 0036653135     PISSN: 00094722     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00104-002-0453-1     Document Type: Article
Times cited : (16)

References (25)
  • 1
    • 0029039982 scopus 로고
    • Expression of plateled derived growth factor B-chain and the plateled derived growth factor receptor β-subunit in human breast tissue and breast carcinoma
    • Coltrera MD, Wang J, Porter PL, Gown AM (1995) Expression of plateled derived growth factor B-chain and the plateled derived growth factor receptor β-subunit in human breast tissue and breast carcinoma. Cancer Res 55:2703-2708
    • (1995) Cancer Res , vol.55 , pp. 2703-2708
    • Coltrera, M.D.1    Wang, J.2    Porter, P.L.3    Gown, A.M.4
  • 2
    • 0034923721 scopus 로고    scopus 로고
    • Expression of growth factors, growth factor receptors and apoptosis related proteins in breast cancer: Relation to apoptotic rate
    • De Jong JS, van Diest PJ, van der Valk P, Baak JP (2001) Expression of growth factors, growth factor receptors and apoptosis related proteins in breast cancer: relation to apoptotic rate. Breast Cancer Res Treat Apr 66:201-208
    • (2001) Breast Cancer Res Treat Apr , vol.66 , pp. 201-208
    • De Jong, J.S.1    Van Diest, P.J.2    Van Der Valk, P.3    Baak, J.P.4
  • 3
    • 0025141337 scopus 로고
    • What is the evidence that tumors are angiogenesis dependent?
    • Folkman J (1990) What is the evidence that tumors are angiogenesis dependent? J Natl Cancer Inst 82:4-6
    • (1990) J Natl Cancer Inst , vol.82 , pp. 4-6
    • Folkman, J.1
  • 4
    • 85013312416 scopus 로고
    • Tumour angiogenesis: Therapeutic implications
    • Folkman J (1971) Tumour angiogenesis: therapeutic implications. N Engl J Med 285:1182-1186
    • (1971) N Engl J Med , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 5
    • 0029564858 scopus 로고
    • Tumor angiogenesis as a predictor of recurrence and survival in patients with node-negative colon cancer
    • Frank RE, Saclarides TJ, Leurgans S et al. (1995) Tumor angiogenesis as a predictor of recurrence and survival in patients with node-negative colon cancer. Ann Surg 222:695-699
    • (1995) Ann Surg , vol.222 , pp. 695-699
    • Frank, R.E.1    Saclarides, T.J.2    Leurgans, S.3
  • 6
    • 0027952211 scopus 로고
    • Quantification of intratumoral vascularization predicts metastasis in human invasive solid tumors
    • Gasparini G (1994). Quantification of intratumoral vascularization predicts metastasis in human invasive solid tumors.Oncol Rep 1:7-12
    • (1994) Oncol Rep , vol.1 , pp. 7-12
    • Gasparini, G.1
  • 7
    • 0028951043 scopus 로고
    • Dormancy of micrometastases: Balanced proliferation and apoptosis in the presence of angiogenesis suppression
    • Holmgren L, O'Reilly MS, Folkman J (1995) Dormancy of micrometastases: balanced proliferation and apoptosis in the presence of angiogenesis suppression. Nat Med 1:149-153
    • (1995) Nat Med , vol.1 , pp. 149-153
    • Holmgren, L.1    O'Reilly, M.S.2    Folkman, J.3
  • 8
    • 0347982648 scopus 로고    scopus 로고
    • Leflunomide vs Sulfasalazin in rheumatoid arthritis: 24 month update of a randomized double - Blind study
    • Abstract 1202
    • Kalden JR, Schattenkirchner M, Smolen JS (2000). Leflunomide vs Sulfasalazin in rheumatoid arthritis: 24 month update of a randomized double - blind study. Arth Rheum 42 [Suppl]:Abstract 1202
    • (2000) Arth Rheum , vol.42 , Issue.SUPPL.
    • Kalden, J.R.1    Schattenkirchner, M.2    Smolen, J.S.3
  • 9
    • 0035878997 scopus 로고    scopus 로고
    • Pharmacodynamic-mediated reduction of temozolomide tumor concentrations by the angiogenesisinhibitorTNP-470
    • Ma J, Pulfer S, Li S, Chu J, Reed K, Gallo JM (2001) Pharmacodynamic-mediated reduction of temozolomide tumor concentrations by the angiogenesisinhibitorTNP-470.Cancer Res 61:5491-5498
    • (2001) Cancer Res , vol.61 , pp. 5491-5498
    • Ma, J.1    Pulfer, S.2    Li, S.3    Chu, J.4    Reed, K.5    Gallo, J.M.6
  • 10
    • 0027501428 scopus 로고
    • Inhibition of the epidermal growth factor receptor tyrosine kinase activity by leflunomide
    • Mattar T, Kochhar K, Bartlett R, Bremer EG, Finnegan A (1995) Inhibition of the epidermal growth factor receptor tyrosine kinase activity by leflunomide. FEBS Lett 334:161-164
    • (1995) FEBS Lett , vol.334 , pp. 161-164
    • Mattar, T.1    Kochhar, K.2    Bartlett, R.3    Bremer, E.G.4    Finnegan, A.5
  • 11
    • 12244277954 scopus 로고    scopus 로고
    • Development of SU5416, a selective small molecule inhibitor of VEGF receptor tyrosine kinase activity, as an anti-angiogenesis agent
    • Review
    • Mendel DB, Laird AD, Smolich BD, Blake RA et al. (2000) Development of SU5416, a selective small molecule inhibitor of VEGF receptor tyrosine kinase activity, as an anti-angiogenesis agent. Anticancer Drug Des 15:29-41 (Review)
    • (2000) Anticancer Drug des , vol.15 , pp. 29-41
    • Mendel, D.B.1    Laird, A.D.2    Smolich, B.D.3    Blake, R.A.4
  • 13
    • 84920241849 scopus 로고
    • Epidermal growth factor receptors in human bladder cancer: Comparison of invasive and superficial tumors
    • Neal DE, Marsh C, Bennett MK, Abel PD et al. (1985) Epidermal growth factor receptors in human bladder cancer: comparison of invasive and superficial tumors. Lancet 1:366-368
    • (1985) Lancet , vol.1 , pp. 366-368
    • Neal, D.E.1    Marsh, C.2    Bennett, M.K.3    Abel, P.D.4
  • 14
    • 0027970092 scopus 로고
    • Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by Lewis lung carcinoma
    • O'Reilly MS, Holmgren L, Shing Y et al. (1994) Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by Lewis lung carcinoma.Cell 79:315-328
    • (1994) Cell , vol.79 , pp. 315-328
    • O'Reilly, M.S.1    Holmgren, L.2    Shing, Y.3
  • 15
    • 0001491497 scopus 로고    scopus 로고
    • Leflunomid zur Behandlung der rheumatoiden Arthritis
    • Reinhold-Keller E, Gross WL (2001) Leflunomid zur Behandlung der rheumatoiden Arthritis. Dtsch Ärztebl 98;29:1502-1507
    • (2001) Dtsch Ärztebl , vol.98 , Issue.29 , pp. 1502-1507
    • Reinhold-Keller, E.1    Gross, W.L.2
  • 16
    • 0030811256 scopus 로고    scopus 로고
    • Inhibition of plateled derived growth factor mediated signal transduction and tumor growth by N-[4-(trifluormethyl)-phenyl]5-methylisoxazole-4-carboxamide
    • Shawver LK, Schwartz DP, Mann E et al. (1997) Inhibition of plateled derived growth factor mediated signal transduction and tumor growth by N-[4-(trifluormethyl)-phenyl]5-methylisoxazole-4-carboxamide. Clin Cancer Res 3:1167-1177
    • (1997) Clin Cancer Res , vol.3 , pp. 1167-1177
    • Shawver, L.K.1    Schwartz, D.P.2    Mann, E.3
  • 17
    • 0032748385 scopus 로고    scopus 로고
    • Antitumor activity of thalidomide in refractory multiple myeloma
    • Singhal S, Mehta J, Desikan R et al. (1999) Antitumor activity of thalidomide in refractory multiple myeloma. NEJM 341:1565-1571
    • (1999) NEJM , vol.341 , pp. 1565-1571
    • Singhal, S.1    Mehta, J.2    Desikan, R.3
  • 19
    • 0033134764 scopus 로고    scopus 로고
    • Bone marrow neovascularization, plasma cell angiogenic potential and matrix metalloproteinase-2 secretion parallel progression of human multiple myeloma
    • Vacca A, Ribatti D, Presta M et al. (1999) Bone marrow neovascularization, plasma cell angiogenic potential and matrix metalloproteinase-2 secretion parallel progression of human multiple myeloma. Blood 93:3054-3073
    • (1999) Blood , vol.93 , pp. 3054-3073
    • Vacca, A.1    Ribatti, D.2    Presta, M.3
  • 20
    • 0027717345 scopus 로고
    • Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma
    • Weidner N, Carroll PR, Flax J, Blumefeld W, Folkman J (1993) Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma. Am J Pathol 143:401-409
    • (1993) Am J Pathol , vol.143 , pp. 401-409
    • Weidner, N.1    Carroll, P.R.2    Flax, J.3    Blumefeld, W.4    Folkman, J.5
  • 21
    • 0032845287 scopus 로고    scopus 로고
    • In vitro and in vivo antitumor activity of a novel immunomodulatory drug, leflunomide: Mechanisms of action
    • Xu X, Shen J, Mall JW et al.(1999) In vitro and in vivo antitumor activity of a novel immunomodulatory drug, leflunomide: mechanisms of action. Biochem Pharmacol 58:1405-1413
    • (1999) Biochem Pharmacol , vol.58 , pp. 1405-1413
    • Xu, X.1    Shen, J.2    Mall, J.W.3
  • 22
    • 0029052321 scopus 로고
    • Inhibition of protein tyrosine kinase phosphorylation in T cells by a novel immunosuppressive agent, leflunomide
    • Xu X, Williams JW, Bremer EG, Finnegan A, Chong ASF (1995) Inhibition of protein tyrosine kinase phosphorylation in T cells by a novel immunosuppressive agent, leflunomide. J Biol Chem 270:12398-12403
    • (1995) J Biol Chem , vol.270 , pp. 12398-12403
    • Xu, X.1    Williams, J.W.2    Bremer, E.G.3    Finnegan, A.4    Chong, A.S.F.5
  • 23
    • 0034085545 scopus 로고    scopus 로고
    • Evaluation of early response to SU101 target-based therapy in patients with recurrent supratentorial malignant gliomas using FDG PET and Gd-DTPA MRI
    • Vlassenko AG, Thiessen B, Beattie BJ, Malkin MG, Blasberg RG (2000) Evaluation of early response to SU101 target-based therapy in patients with recurrent supratentorial malignant gliomas using FDG PET and Gd-DTPA MRI. J Neurooncol 46:249-259
    • (2000) J Neurooncol , vol.46 , pp. 249-259
    • Vlassenko, A.G.1    Thiessen, B.2    Beattie, B.J.3    Malkin, M.G.4    Blasberg, R.G.5
  • 24
    • 0030667205 scopus 로고    scopus 로고
    • From bench top to bedside
    • Barinaga M (1997) From bench top to bedside. Science 278:1036-1039
    • (1997) Science , vol.278 , pp. 1036-1039
    • Barinaga, M.1
  • 25
    • 0035890446 scopus 로고    scopus 로고
    • Inhibition of angiogenesis-related endothelial activity by the experimental immunosuppressive agent leflunomide
    • Waldman WJ, Bickerstaff A, Gordillo G, Orosz K, Knight DA, Orosz CG (2001) Inhibition of angiogenesis-related endothelial activity by the experimental immunosuppressive agent leflunomide. Transplantation 72:1578-1582
    • (2001) Transplantation , vol.72 , pp. 1578-1582
    • Waldman, W.J.1    Bickerstaff, A.2    Gordillo, G.3    Orosz, K.4    Knight, D.A.5    Orosz, C.G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.