GEM 231, a second-generation antisense agent complementary to protein kinase A RIalpha subunit, potentiates antitumor activity of irinotecan in human colon, pancreas, prostate and lung cancer xenografts.

International journal of oncology

Volumn 21, Issue 1, 2002, Pages 65-72

  Agrawal, Sudhir ^a   Kandimalla, Ekambar R ^a   Yu, Dong ^a   Ball, Robin ^a   Lombardi, Gina ^a   Lucas, Terri ^a   Dexter, Daniel L ^a   Hollister, Beth A ^a   Chen, Shih Fong ^a  

^a HYBRIDON INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; ANTISENSE OLIGONUCLEOTIDE; CAMPTOTHECIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; DRUG DERIVATIVE; GENE EXPRESSION MODULATOR 231; IRINOTECAN; OLIGONUCLEOTIDE;

ANIMAL; ARTICLE; BODY WEIGHT; CANCER TRANSPLANTATION; COLON TUMOR; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; EXPERIMENTAL NEOPLASM; FEMALE; GENETICS; HUMAN; LUNG TUMOR; MALE; METABOLISM; MOUSE; NUDE MOUSE; PANCREAS TUMOR; PROSTATE TUMOR; SURVIVAL RATE; TREATMENT OUTCOME;

ANIMALS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BODY WEIGHT; CAMPTOTHECIN; COLONIC NEOPLASMS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; LUNG NEOPLASMS; MALE; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; NEOPLASMS, EXPERIMENTAL; OLIGONUCLEOTIDES; OLIGONUCLEOTIDES, ANTISENSE; PANCREATIC NEOPLASMS; PROSTATIC NEOPLASMS; SURVIVAL RATE; TREATMENT OUTCOME;

EID: 0036652941     PISSN: 10196439     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (0)