Cardiac chimerism as a mechanism for self-repair: Does it happen and if so to what degree?

Circulation

Volumn 106, Issue 1, 2002, Pages 2-4

  Taylor, Doris A ^a   Hruban, Ralph ^a   Rodriguez, E Rene ^a   Goldschmidt Clermont, Pascal J ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Cells; Editorials; Myocytes; Regeneration; Transplantation

Indexed keywords

ALLOGRAFT; CELL DIFFERENTIATION; CHIMERA; EDITORIAL; HEART INJURY; HEART MUSCLE; HUMAN; MUSCLE REGENERATION; PRIORITY JOURNAL;

CELL MOVEMENT; CELL NUCLEUS; FEMALE; HEART; HEART TRANSPLANTATION; HUMANS; LYMPHOCYTES; MALE; MUSCLE, SMOOTH, VASCULAR; MYOCARDIUM; REGENERATION; STEM CELLS; TRANSPLANTATION CHIMERA; Y CHROMOSOME;

EID: 0036645015     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000024386.99599.4A     Document Type: Editorial

References (15)

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3. Regenerating functional myocardium: Improved myocardial performance after skeletal myoblast transplantation
4. Smooth muscle cells, but not myocytes, of host origin in transplanted human hearts
5. Chimerism of the transplanted heart
6. Fluorescence in situ hybridization for the Y-chromosome can be used to detect cells of recipient origin in allografted hearts following cardiac transplantation
7. Evidence for cardiomyocyte repopulation by extracardiac progenitors in transplanted human hearts
8. Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function
9. Contribution of monocytes/macrophages to compensatory neovascularization: The drilling of metalloelastase-positive tunnels in ischemic myocardium
10. Characterization of myocyte enhancer factor 2 (MEF2) expression in B and T cells: MEF2C is a B cell-restricted transcription factor in lymphocytes
11. Deletion of calcineurin and myocyte enhancer factor 2 (MEF2) binding domain of Cabin 1 results in enhanced cytokine gene expression in T cells
12. Mouse GATA-4: A retinoic acid-inducible GATA-binding transcription factor expressed in endodermally derived tissues and heart
13. Of the GATA-binding proteins, only GATA-4 selectively regulates the human IL-5 gene promoter in IL-5 producing cells which express multiple GATA-binding proteins
14. Preclinical diagnosis of familial hypertrophic cardiomyopathy by genetic analysis of blood lymphocytes
15. Modification of expression of stem cell factor by various cytokines