Intelligent thermoresponsive polymeric stationary phases for aqueous chromatography of biological compounds

Progress in Polymer Science (Oxford)

Volumn 27, Issue 6, 2002, Pages 1165-1193

  Kikuchi, Akihiko ^a   Okano, Teruo ^a  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

Author keywords

Aqueous mobile phase; Bioactive compounds; Biocompatibility; Charge density alteration; Chromatography; Dye affinity chromatography; Hydrophilic hydrophobic property alteration; Penetration control; Separation; Stimuli responsive polymer; Surface function

Indexed keywords

BIOCOMPATIBILITY; CHROMATOGRAPHY; GRAFT COPOLYMERS; INTELLIGENT MATERIALS; INTERFACES (MATERIALS); SEPARATION;

STIMULI RESPONSIVE POLYMERS;

POLYAMIDES;

EID: 0036643904     PISSN: 00796700     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0079-6700(02)00013-8     Document Type: Review

References (71)

1. Intelligent polymeric materials for drug delivery
2. Molecular design of temperature-responsive polymers as intelligent materials
3. Intelligent polymers in medicine and biotechnology
4. Solution properties of poly(N-isopropylacrylamide)
5. Temperature dependence of swelling of crosslinked poly(N,N-alkyl substituted acrylamides) in water
6. Temperature-responsive chromatography
7. Preparation and properties of novel environment-sensitive membranes prepared by graft polymerization onto a porous membrane
8. Atomic force microscopic images of solvated polymer brushes
9. Design and synthesis of glucose-sensitive insulin-releasing systems
10. An insulin-releasing system that is responsive to glucose
11. Thermoselective permeation from a polymer-grafted capsule membrane
12. Preparation of temperature-sensitive membranes by graft polymerization onto a porous membrane
13. Thermoprecipitation of streptavidin via oligonucleotide-mediated self-assembly with poly(N-isopropylacrylamide)
14. Control of protein-ligand recognition using a stimuli-responsive polymer
15. Site-specific conjugation of a temperature-sensitive polymer to a genetically-engineered protein
16. Gel permeation chromatography using porous glass beads modified with temperature-responsive polymers
17. In situ surface-selective modification of uniform size macroporous polymer particles with temperature-responsive poly-N-isopropylacrylamide
18. Temperature-controlled high-performance liquid chromatography using a uniformly sized temperature-responsive polymer-based packing material
19. Temperature-responsive size-exclusion chromatography using poly(N-isopropylacrylamide) grafted silica
20. Effects of mobile-phase composition and temperature on the selectivity of poly(N-isopropylacrylamide)-bonded silica gel in reversed-phase liquid chromatography
21. Dynamic contact angle measurement of temperature-responsive surface properties for poly(N-isopropylacrylamide) grafted surfaces
22. Graft architectural effects on thermo-responsive wettability changes of poly(N-isopropylacrylamide)-modified surfaces
23. Effects of cross-linked structure on temperature-responsive hydrophobic interaction of PIPAAm hydrogel modified surfaces with steroids
24. Thermal recovery of cells cultured on poly(N-isopropylacrylamide) surface-grafted polystyrene dishes
25. Wilhelmy plate measurements on poly(N-isopropylacrylamide)-grafted surfaces
26. Reversible surface properties of glass plate and capillary tube grafted by photopolymerization of N-isopropylacrylamide
27. Plasma polymerized N-isopropylacrylamide: Synthesis and characterization of a smart thermally responsive coating
28. Morphological and immuno-cytochemical characterization of a heterospheroid composed of fibroblasts and hepatocytes
29. Cell culture on a thermo-responsive polymer surface
30. Thermo-responsive polymeric surfaces; Control of attachment and detachment of cultured cells
31. A novel recovery system for cultured cells using plasma-treated polystyrene dishes grafted with poly(N-isopropylacrylamide)
32. Mechanism of cell detachment from temperature-modulated, hydrophilic-hydrophobic polymer surfaces
33. Retinal pigmented epithelium cultures on thermally responsive polymer porous substrates
34. Temperature-responsive culture dishes allow nonenzymatic harvest of differentiated Madin-Darby canine kidney (MDCK) cell sheets
35. Two-dimensional manipulation of confluently cultured vascular endothelial cells using temperature-responsive poly(N-isopropylacrylamide)-grafted surfaces
36. Decrease in culture temperature releases monolayer endothelial cell sheets together with deposited fibronectin matrix from temperature-responsive culture surfaces
37. Creation of designed shape cell sheets that are noninvasively harvested and moved onto another surface
38. Rapid cell sheet detachment from poly(N-isopropylacrylamide)-grafted porous cell culture membranes
39. Thermo-responsive culture dishes allow the intact harvest of multilayered keratinocyte sheets without dispose by reducing temperature
40. Two-dimensional cell sheet manipulation of heterotypically co-cultured lung cells utilizing temperature-responsive culture dishes results in long-term maintenance of differentiated epithelial cell functions
41. Preliminary report on cell culture on a thermally reversible copolymer
42. Patterned immobilization of thermoresponsive polymer
43. Temperature-responsive chromatography using poly(N-isopropylacrylamide)-modified silica
44. Temperature-responsive bioconjugates. 1. Synthesis of temperature-responsive oligomers with reactive end groups and their coupling to biomolecules
45. Temperature-responsive liquid chromatography. 2. Effect of hydrophobic groups in N-isopropylacrylamide copolymer-modified silica
46. Analysis of peptides and proteins by temperature-responsive chromatographic system using N-isopropylacrylamide polymer-modified columns
47. Temperature-responsive chromatographic separation of amino acid phenylthiohydantoins using aqueous media as the mobile phase
48. Temperature-responsive chromatographic separation of bisphenol A with water as a sole mobile phase
49. Native purification of biomolecules with temperature-mediated hydrophobic modulation liquid chromatography
50. Kinetics of discontinuous volume-phase transition of gels
51. Comb-type grafted hydrogels with rapid temperature responses
52. Separation of acidic bioactive compounds by aqueous chromatography using thermo-responsive cationic surfaces
53. Mutual influence of pH and temperature on the swelling of ionizable and thermosensitive hydrogels
54. Aqueous chromatography utilizing pH-/temperature-responsive polymer stationary phases to separate ionic bioactive compounds
55. Free energy transduction in polypeptides and proteins based on inverse temperature transitions
56. a shifts for aspartic acid: Relevance to protein mechanisms
57. Alkaline extraction and reverse-phase high-performance liquid chromatography of adenine and pyridine nucleotides in human platelets
58. Simultaneous determination of creatine compounds and adenine nucleotides in myocardial tissue by high-performance liquid chromatography
59. Isocratic separation of ATP and its degradation products from biological fluids by automated liquid chromatography
60. Enzymatic synthesis of ATP analogs and their purification by reversed-phase high-performance liquid chromatography
61. Adenine nucleotides and adenosine metabolism in pig kidney proximal tubule membranes
62. Effect of synthetic polymers, poly(N-vinyl pyrrolidone) and poly(N-vinyl caprolactam), on elution of lactate dehydrogenase bound to blue Sepharose
63. Temperature-induced displacement of proteins from dye-affinity columns using an immobilized polymeric displacer
64. Affinity separations of proteins