Formulation and optimization of a sustained-release tablet of Ketorolac tromethamine

Drug Delivery: Journal of Delivery and Targeting of Therapeutic Agents

Volumn 9, Issue 3, 2002, Pages 153-159

  Vatsaraj, Neha ^a   Zia, Hossein ^a   Needham, Thomas ^a  

^a UNIVERSITY OF RHODE ISLAND   (United States)

Author keywords

Dissolution; Ethylcellulose; HPMC; Hydrophilic Matrix Tablet; Ketorolac Tromethamine; Sodium CMC; Sustained Release

Indexed keywords

CARBOXYMETHYLCELLULOSE; ETHYL CELLULOSE; HYDROXYPROPYLMETHYLCELLULOSE; KETOROLAC TROMETAMOL;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; DRUG FORMULATION; DRUG HALF LIFE; DRUG SOLUBILITY; GASTROINTESTINAL TRACT; HYDROPHILICITY; PRIORITY JOURNAL; STATISTICAL MODEL; SUSTAINED RELEASE PREPARATION; TABLET FRIABILITY;

CHEMISTRY, PHARMACEUTICAL; COMPRESSIVE STRENGTH; DELAYED-ACTION PREPARATIONS; KETOROLAC TROMETHAMINE; SOLUBILITY; TABLETS;

EID: 0036637718     PISSN: 10717544     EISSN: None     Source Type: Journal    
DOI: 10.1080/10426500290095656     Document Type: Article

References (21)

1. RS-37619 and aspirin analgesia for postpartum uterine cramps
2. Ketorolac: A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential
3. Drug diffusion front movement is important in drug release control from swellable matrix tablets
4. Swelling activated drug delivery systems
5. Multi-layered hydrophilic matrices as constant release devices (Geomatrixsup™ systems)
6. Mathamatical model for enteric film coating of tablets
7. Drug release from compressed hydrophilic POLYOX-WSR tablets
8. A new ternary polymeric matrix system for controlled drug delivery of highly soluble drugs: I diltiazem hydrochloride
9. Present and future applications of biomaterials in controlled drug delivery systems
10. Identification of critical formulation and processing variables for metroprolol tartrate extended-release (ER) matrix tablets
11. A simple equation for description of solute release II: Fickian and anomalous release from swellable devices
12. Permeability of pure ehantimers of ketorolac through human cadaver skin
13. Effect of polymers and microspheres on nasal absorption of insulin in rats
14. Computer optimization of pharmaceutical formulations
15. Zero-order release kinetics from self-correcting, floatable asymmetric configuration drug delivery system
16. The analgesic efficacy of (±)-5-benzoyl-1,2-dihydro-3H-prrolo [1,2a] pyrrole-1-carboxylic acid, tromethamine salt in post-operative pain
17. Analgesia from intramuscular ketorolac tromethamine compared to morphine sulfate in severe pain following major surgery