Recurrent thromboembolism in a patient with β-thalassemia major associated with double heterozygosity for factor V R506Q and prothrombin G20210A mutations

Blood Coagulation and Fibrinolysis

Volumn 13, Issue 5, 2002, Pages 461-463

  Kahn, J E ^a   Veyssier Belot, C ^a   Renier, J L ^a   De Mazancourt, P ^a   Peltier, J Y ^a   De Raucourt, Emmanuelle ^a  

^a Poissy St Germain en Laye Hospital   (France)

Author keywords

Factor V Leiden; Major thalassemla; Prothrombin G20210A mutation

Indexed keywords

ACETYLSALICYLIC ACID; ANTICOAGULANT AGENT; ANTITHROMBIN; BLOOD CLOTTING FACTOR 5; CARDIOLIPIN ANTIBODY; HEPARIN; HYDROXYUREA; LOW MOLECULAR WEIGHT HEPARIN; PROTEIN C; PROTEIN S; PROTHROMBIN;

ADULT; ARTICLE; BETA THALASSEMIA; BLOOD CLOTTING; BLOOD TRANSFUSION; CASE REPORT; CELL COUNT; DEEP VEIN THROMBOSIS; ERYTHROBLAST; ERYTHROCYTE; GENE MUTATION; GENETIC STRAIN; HEMOGLOBIN DETERMINATION; HETEROZYGOSITY; HUMAN; INTENSIVE CARE; LONG TERM CARE; LUNG EMBOLISM; MALE; PERIPHERAL VEIN; PHLEBOGRAPHY; POPLITEAL VEIN; PRIORITY JOURNAL; RISK FACTOR; SHORT COURSE THERAPY; SPLENECTOMY; THROMBOCYTE COUNT; THROMBOCYTOPATHY; THROMBOEMBOLISM; THROMBOPHILIA; THROMBOSIS; TIME; VEIN THROMBOSIS;

3' UNTRANSLATED REGIONS; ACTIVATED PROTEIN C RESISTANCE; ADULT; ANTICOAGULANTS; ASPIRIN; BETA-THALASSEMIA; FACTOR V; GENETIC PREDISPOSITION TO DISEASE; HEPARIN, LOW-MOLECULAR-WEIGHT; HETEROZYGOTE; HUMANS; MALE; POPLITEAL VEIN; PROTHROMBIN; PULMONARY EMBOLISM; RECURRENCE; SAPHENOUS VEIN; SPLENECTOMY; THROMBOPHILIA; THROMBOPHLEBITIS;

EID: 0036631123     PISSN: 09575235     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001721-200207000-00012     Document Type: Article

References (7)

1. Thromboembolic events in beta thalassemia major: An Italian multicenter study
2. A chronic hypercoagulable state in patients with beta-thalassemia major is already present in childhood
3. Increased procoagulant activity, of red blood cells from patients with homozygous sickle cell disease and β-thalassemia
4. Venous thromboembolism and hypercoagulability in splenectomized patients with thalassemia intermedia
5. Combined effect of factor V Leiden and prothrombine 20210 A on the risk of venous thromboembolism
6. Resistance to protein C in thalassemic patients: An underlying cause of thrombosis
7. Thrombophilia in thalassemia major patients: Analysis of genetic predisposing factors