Molecular design based on 3D-pharmacophore. Application to 5-HT4 receptor

Journal of Chemical Information and Computer Sciences

Volumn 42, Issue 4, 2002, Pages 962-967

  Bureau, Ronan ^a   Daveu, Cyril ^a   Lemaître, Stéphane ^a   Dauphin, François ^a   Landelle, Henriette ^a   Lancelot, Jean Charles ^a   Rault, Sylvain ^a  

^a CENTRE D ETUDES ET DE RECHERCHE SUR LE MÉDICAMENT DE NORMANDIE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

STRUCTURAL MODIFICATION;

CONFORMATIONS; DERIVATIVES; HYDROGEN BONDS; HYDROPHOBICITY; MOLECULAR STRUCTURE; SYNTHESIS (CHEMICAL);

PHARMACODYNAMICS;

LIGAND; SEROTONIN 4 RECEPTOR; SEROTONIN AGONIST; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR;

ARTICLE; CHEMICAL MODEL; CHEMISTRY; COMPARATIVE STUDY; COMPUTER AIDED DESIGN; COMPUTER PROGRAM; COMPUTER SIMULATION; DRUG DESIGN; DRUG EFFECT; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

COMPUTER SIMULATION; COMPUTER-AIDED DESIGN; DRUG DESIGN; LIGANDS; MODELS, CHEMICAL; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT4; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; SOFTWARE;

EID: 0036628564     PISSN: 00952338     EISSN: None     Source Type: Journal    
DOI: 10.1021/ci0101354     Document Type: Article

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