Chaperon Hsp-60 as autoantigen in development of dyshormonal breast diseases

Experimental Oncology

Volumn 24, Issue 2, 2002, Pages 112-115

  Vigontina, O G ^a   Efimenko, O A ^b   Yakovenko, L F ^a   Kiyamova, R G ^a   Filonenko, V V ^a   Gout, I T ^c   Ros, N V ^b   Kosey, N V ^b   Tatarchuk, T F ^b   Sidorik, L L ^a   Matsuka, G Kh ^a  

^a INSTITUTE OF MOLECULAR BIOLOGY AND GENETICS   (Ukraine)

^b Ukrainian Inst Pediat Obstet G   (Ukraine)

^c LUDWIG INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

Author keywords

Breast cancer; Chaperon; Dyshormonal breast diseases

Indexed keywords

AUTOANTIGEN; CHAPERONE; HEAT SHOCK PROTEIN 60; PROTEIN ANTIBODY;

ANTIBODY DETECTION; ANTIGEN DETECTION; ANTIGEN PURIFICATION; ARTICLE; AUTOIMMUNITY; BACTERIAL CELL; BREAST CANCER; BREAST DISEASE; CELL TRANSFORMATION; CLINICAL ARTICLE; CONTROLLED STUDY; ESCHERICHIA COLI; FEMALE; GEL FILTRATION; HUMAN; HUMAN TISSUE; PLASMID;

EID: 0036626622     PISSN: 02043564     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Kendall BS, Ronnet BM, Isacson C. Reproducibility of the diagnosis of endometrial hyperplasia, atypical hyperplasia and well-differentiated carcinoma. Am J Surg Pathol 1998; 1: 1012-9.
2. Eskin BA, Asbell SO, Jardines L. Breast disease for primary care physicians. New-York - London: Partenon Publishing Group 1999. 65-75 pp.
3. th edition). London: Partenon Publishing Group 1999. 839 p.
4. Sidorova IS, Sarantsev AN, Piddubniy MI, Levakov SA, Matvienko NA. The state of the breast in patients with hyperplastic processes and endometrium cancer during postmenopause. Obstetr Ginecol 2000; (3): 53-6 (In Russian).
5. Duda IV, Gerasimova LN. Associated hormonal dependent diseases of uterus and breast. Zdravoohranenie 1996; (12): 3-8 (In Russian).
6. Russo J, Russo IH. Role of hormones in human breast development: the menopausal breast. In: Menopause biology and pathobiology. Lobo RA, ed. New York 1996. 184-93 pp.
7. Tan EM. Autoimmunity and apoptosis. J Exp Med 1994; 179: 1083-6.
8. Sidorik LL, Rodnin NV, Bobyk VI, Ryabenko DV, Veberov AV, Tkachenko TYu, Matsuka GKh. Investigation of autoantibodies directed against tissue-specific myocardial antigens in dilated cardiomyopathy. Biopolymers Cell 1995; 11: 81-6.
9. Sidorik LL, Rybkinska TA, Vigontina OG, Vudmaska MI, Naidenov VG, Pogribnyi PV, Lisovskii IL, Schvachko LP, Bronstein I, Lyzogubov VV, Prihod'ko EA, Usenko VS, Matsuka GKh. Investigation of DNA topoisomerase as an autoantigen at the thyroid cancer. Biopolymers Cell 2001; 17: 551-5.
10. Sidorik LL, Todurov IM, Vigontina OG, Ribkinska TA, Vudmaska MI, Naidenov VG, Kopchak VM, Matsuka GKh. Anti-DNA-topoisomerase antibodies in the blood serum in the pathology of pancreas. Exp Oncol 2001; 23: 153-6 (In Russian).
11. Gething MJ, Sambrook J. Protein folding in the cell. Nature 1992; 355 (6355): 33-45.
12. Thomas P, Qu B-H, Pedersen P. Defective protein folding as a basis of human disease. TIBS 1995; 20: 456-9.
13. Witkin SS, Askienazy-Elbhar M, Henry-Suchet J, Belaish-Allart J, Tort-Grumbach J, Sarjdine K. Circulating antibodies to a conserved epitope of the Chlamidia trachomatis 60 kDa heat shock protein (Hsp-60) in infertile couples and its relationship to antibodies to C.trachomatis surface antigens and Escherichia coli and human HSP-60. Human Reprod 1998; 13: 1175-9.
14. Hubtinen M, Puolakkainen M, Laasita K, Sarvas M, Karma A, Leirisalo-Repo M. Chlamidial antibodies in patients with previous acute anterior uveitis. Invest Ophtalmol Visual Sci 2001; 42: 1816-9.
15. Sidorik LL, Vigontina OG, Ribkinska TA, Pogrebnoy PV, Efimenko OA, Ros' NV, Kosey NV, Tatarchuk TF, Matsuka GKh. The study of DNA-topoisomerase 1 as auto-antigen in development of dyshormonal diseases of the breast. Dopov NAS Ukraine 2002; in press (In Russian).
16. Sidorik LL, Rodnin NV, Savinskaya LA, Rybkinska TA, Rojko OT, Korneluk AI, Matsuka GKh. Auto-antibodies to tyrosyl-tRNA synthetase modulate its aminoacylating activity. Biopolymers Cell 1996; 12: 21-8.
17. Laemmli UK. Cleavage of structural proteins during the assembly of the bacteriophage T4. Nature 1970; 227: 680-5.
18. Bradford MM. A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein binding. Anal Biochem 1976; 81: 193-200.
19. Guilbert B, Dighiero G, Avrameas S. Naturally occuring antibodies against nine common antigens in human sera. I. Detection, isolation and characterization. J Immunol 1982; 128: 2779-87.
20. Raz E, Ben-Bassat H, Davidi T, Schlomai, Eilat D. Cross-reactions of anti-DNA autoantibodies with cell surface proteins. Eur J Immunol 1993; 23: 383-90.
21. Pratt WB. The role of heat shock proteins in regulating the function, folding, and trafficking of the glucocorticoid receptor. J Biol Chem 1993; 268: 21455-8.